Results 21 to 30 of about 127,756 (395)

Arabidopsis PEN3/PDR8, an ATP Binding Cassette Transporter, Contributes to Nonhost Resistance to Inappropriate Pathogens That Enter by Direct Penetration[W][OA]

The Plant Cell Online, 2006
Arabidopsis thaliana is a host to the powdery mildew Erysiphe cichoracearum and nonhost to Blumeria graminis f. sp hordei, the powdery mildew pathogenic on barley (Hordeum vulgare).
Monica Stein, Jan Dittgen, Clara Sánchez-Rodríguez, B. Hou, A. Molina, P. Schulze-Lefert, V. Lipka, S. Somerville   +7 more
semanticscholar   +1 more source

Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8

Journal of Lipid Research, 2005
The ATP binding cassette transporters ABCG5 (G5) and ABCG8 (G8) limit the accumulation of neutral sterols by restricting sterol uptake from the intestine and promoting sterol excretion into bile.
Liqing Yu, Klaus von Bergmann, Dieter Lütjohann, Helen H. Hobbs, Jonathan C. Cohen   +4 more
doaj   +1 more source

Proton Motive Force-Dependent Hoechst 33342 Transport by the ABC Transporter LmrA of Lactococcus lactis [PDF]

, 2005
The fluorescent compound Hoechst 33342 is a substrate for many multidrug resistance (MDR) transporters and is widely used to characterize their transport activity.
Abbreviations ABC, Chen M., Doerrler W. T., Ecker G. F., Gajic O., Haugland R. P., Higuchi R., Ketchum C. J., Kuipers O. P., Lalande M. E., Lanzetta P. A., Lewinson O., Linnett P. E., Lubelski J., Lubelski J., Margolles A., Mazurkiewicz P., Orelle C., Paternostre M. T., Poelarends G. J., Putman M., Sakamoto K., Sambrook J., Shapiro A. B., Shapiro A. B., Shapiro A. B., Shapiro A. B., Sharma S., Steinfels E., Urbatsch I. L., van Veen H. W., van Veen H. W., van Veen H. W., Venter H., Viitanen P., Yu J. L.   +35 more
core   +2 more sources

Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7

Journal of Lipid Research, 2005
The assembly of HDL by helical apolipoprotein and cellular lipid was studied using HEK293 cells to which ecdysone-inducible human ABCA1 or human ABCA7 was transfected.
Michi Hayashi, Sumiko Abe-Dohmae, Mitsuyo Okazaki, Kazumitsu Ueda, Shinji Yokoyama   +4 more
doaj   +1 more source

Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor

Membranes, 2021
ABCB1/P-glycoprotein is an ATP binding cassette transporter that is involved in the clearance of xenobiotics, and it affects the disposition of many drugs in the body.
Alessandro Barbieri, Nopnithi Thonghin, Talha Shafi, Stephen M. Prince, Richard F. Collins, Robert C. Ford   +5 more
doaj   +1 more source

Structures and functions of mitochondrial ABC transporters [PDF]

, 2015
A small number of physiologically important ATP-binding cassette (ABC) transporters are found in mitochondria. Most are half transporters of the B group forming homodimers and their topology suggests they function as exporters.
Aller, Ardehali, Balk, Bayeva, Belinda Faust, Bernard, Chen, Chen, Chen, Chitra A. Shintre, Chloupková, Christensen, Csere, Dawson, Dudek, Elisabeth P. Carpenter, Feissner, Giegé, Gompf, Graf, Gutmann, Hendrik W. van Veen, Higgins, Higgins, Hofacker, Hogue, Hyde, Ichikawa, Janneke Balk, Jin, Kessler, Kispal, Kispal, Kiss, Kiss, Krishnamurthy, Krüssel, Kuhnke, Kushnir, Lee, Leighton, Li, Liesa, Lill, Lill, Mikolay, Mitsuhashi, Paterson, Pondarré, Pondarré, Poor, Qi, Rayapuram, San Francisco, Schaedler, Senbongi, Shintre, Shirihai, Srinivasan, Teschner, Theresia A. Schaedler, Tiranti, Tsuchida, Vasundara Srinivasan, Ward, Yamamoto, Young, Zhang   +67 more
core   +2 more sources

The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation

Nature Communications, 2022
Ycf1, a C-family member ATP Binding Cassette (ABC) transporter, transports glutathione and glutathione-metal complexes in yeast. Here the authors use cryo-EM and biochemical analysis to show how an intrinsically-disordered regulatory domain (R-domain ...
Nitesh Kumar Khandelwal, Cinthia R. Millan, Samantha I. Zangari, Samantha Avila, Dewight Williams, Tarjani M. Thaker, Thomas M. Tomasiak   +6 more
doaj   +1 more source

Rustless translation [PDF]

, 2012
ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Karl-Peter Hopfner, Roy
core   +1 more source

Activation of NLRP3 Inflammasome Promotes Foam Cell Formation in Vascular Smooth Muscle Cells and Atherogenesis Via HMGB1

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background This study aimed at investigating whether NLRP3 (the Nod like receptor family, pyrin domain‐containing 3 protein) inflammasome activation induced HMGB1 (high mobility group box‐1 protein) secretion and foam cell formation in human vascular ...
Rui Wang, Weibin Wu, Wen Li, Shuichuan Huang, Zilun Li, Ruiming Liu, Zhen Shan, Chunxiang Zhang, Wen Li, Shenming Wang   +9 more
doaj   +1 more source

The ATP-binding cassette transporter A1 regulates phosphoantigen release and Vγ9Vδ2 T cell activation by dendritic cells

Nature Communications, 2017
Vγ9Vδ2 T cells are activated by phosphoantigens, such as isopentenyl pyrophosphate (IPP), which is generated in the mevalonate pathway of antigen-presenting cells. IPP is released in the extracellular microenvironment via unknown mechanisms. Here we show
B. Castella, J. Kopecka, Patrizia Sciancalepore, Giorgia Mandili, M. Foglietta, N. Mitro, D. Caruso, F. Novelli, C. Riganti, M. Massaia   +9 more
semanticscholar   +1 more source