Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
, 2006 Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
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Comparative Mutant Analysis of Arabidopsis ABCC-Type ABC Transporters: AtMRP2 Contributes to Detoxification, Vacuolar Organic Anion Transport and Chlorophyll Degradation [PDF]
, 2017 The enormous metabolic plasticity of plants allows detoxification of many harmful compounds that are generated during biosynthetic processes or are present as biotic or abiotic toxins in their environment.
Azevedo, Louis +9 more
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ABC TRANSZPORTEREK ÚTON ÚTFÉLEN [PDF]
, 2013 A különböző ABC transzporterek igen fontos szerepet látnak el a szervezet határ- felületei anyagforgalmának szabályozásában. Ezek az élettani határolók polari- zált sejtekből állnak, melyek szoros sejtkapcsolattal kapcsolódnak egymáshoz, megakadályozva ...
Homolya, László
core
Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]
, 2017 Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core
Regulation of ATP binding cassette transporter A1 (ABCA1) expression: cholesterol-dependent and - independent signaling pathways with relevance to inflammatory lung disease. [PDF]
Respir Res, 2020 He P, Gelissen IC, Ammit AJ.
europepmc +1 more source
A Chemical Genetic Approach To The Study Of Cellular Transport [PDF]
, 2005 The focus of this thesis is the use of chemical genetics to study two different aspects of membrane biology, (a) the mechanisms underlying cellular lipid transport and (b) the intersection between endocytic and exocytic traffic.
Nieland, T.J.F.
core +2 more sources
Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes. [PDF]
Mol Metab, 2020 Lyu J +10 more
europepmc +1 more source
Regulation of ATP-binding cassette transporter A1 in cholesteryl ester storage disease
, 2009 Previous studies from the Francis laboratory have determined that regulation of ABCA1 expression is impaired in the lysosomal cholesterol storage disorder Niemann-Pick type C (NPC) disease, the presumed reason for the low plasma HDL-cholesterol (HDL-C) levels found in the majority of NPC disease patients.
openaire +1 more source
The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux. [PDF]
J Cell Mol Med, 2019 Lien CC +7 more
europepmc +1 more source