Results 21 to 30 of about 156,745 (364)
Structural View of Cryo-Electron Microscopy-Determined ATP-Binding Cassette Transporters in Human Multidrug Resistance [PDF]
BiomoleculesATP-binding cassette (ABC) transporters, acting as cellular “pumps,” facilitate solute translocation through membranes via ATP hydrolysis. Their overexpression is closely tied to multidrug resistance (MDR), a major obstacle in chemotherapy and ...
Wenjie Fan, Kai Shao, Min Luo
doaj +2 more sources
ATP-binding cassette transporters in reproduction: a new frontier [PDF]
Human Reproduction Update, 2015 The transmembrane ATP-binding cassette (ABC) transporters actively efflux an array of clinically relevant compounds across biological barriers, and modulate biodistribution of many physiological and pharmacological factors. To date, over 48 ABC transporters have been identified and shown to be directly and indirectly involved in peri-implantation ...
Stephen J. Lye +5 more
openaire +4 more sources
Chalcone Derivatives Enhance ATP-Binding Cassette Transporters A1 in Human THP-1 Macrophages [PDF]
Molecules, 2018 Atherosclerosis is a process of imbalanced lipid metabolism in the vascular walls. The underlying pathology mainly involves the deposition of oxidized lipids in the endothelium and the accumulation of cholesterol in macrophages.
I-Jou Teng +8 more
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AMB Express, 2022 Keypoints P. aromaticivorans AR20-38 differentially regulates three main enzymes for the bioconversion of ferulic acid to vanillic acid. ATP binding cassette transporters, major facilitator superfamily transporters and outer membrane vesicles are ...
Caroline Poyntner +3 more
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Frontiers in Pharmacology, 2023 Chemoradiotherapy is frequently used to treat cancer. Stereotactic body radiotherapy (SBRT) is a single high-dose radiotherapy used to treat a variety of cancers.
Kakeru Sato +12 more
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eLife, 2021 ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases.
Erich Stefan +7 more
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Slit Mask Integral Field Units for the Southern African Large Telescope [PDF]
2022, 2022 Two fibre integral field units (IFU) are being built in the SAAO fibre-lab for the Robert Stobie Spectrograph's visible arm and the future red arm. Each IFU sits in its own slit-mask cassette and is referred to as a slit-mask IFU (SMI). They will be available some time in 2022.
arxiv +1 more source
Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2
Technology in Cancer Research & Treatment, 2020 The current researches have reported that circular RNA is an important regulatory factor in the progression of various human disease. However, the function and mechanism of most circular RNAs remain unknown in cancers including multiple myeloma.
Yan Song MD +3 more
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Frontiers in Pharmacology, 2021 Cisplatin is one of the first line anti-cancer drugs prescribed for treatment of solid tumors; however, the chemotherapeutic drug resistance is still a major obstacle of cisplatin in treating cancers. Yu Ping Feng San (YPFS), a well-known ancient Chinese
Yingqing Du +19 more
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Haematologica, 2011 Background A major issue in the treatment of acute myeloid leukemia is resistance to chemotherapeutic drugs. An increasing number of ATP-Binding-Cassette transporters have been demonstrated to cause resistance to cancer drugs.
Christophe Marzac +11 more
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