Results 41 to 50 of about 1,728,775 (305)
Extracellular ATP and Neurodegeneration
Current Drug Target -CNS & Neurological Disorders, 2003 ATP is a potent signaling molecule abundantly present in the CNS. It elicits a wide array of physiological effects and is regarded as the phylogenetically most ancient epigenetic factor playing crucial biological roles in several different tissues. These can range from neurotransmission, smooth muscle contraction, chemosensory signaling, secretion and ...
Volonté, Cinzia +5 more
openaire +3 more sources
ATP ‐ a fast neurotransmitter [PDF]
FEBS Letters, 1993 ATP receptor‐mediated responses in peripheral and central neurones have many characteristics which suggest that ATP may act as a fast neurotransmitter. While the receptors underlying these responses have properties which are similar to other ligand‐gated ion channels which mediate fast neurotransmision, the nature of their calcium permeability and the ...
Alasdair J. Gibb, Frances A. Edwards
openaire +3 more sources
P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes [PDF]
, 2008 ATP plays an important role in signal transduction between neuronal and glial circuits and within glial networks. Here we describe currents activated by ATP in astrocytes acutely isolated from cortical brain slices by non-enzymatic mechanical ...
Kirchhoff, Frank +6 more
core +1 more source
Seismic Upgrading of the Heritage-Protected Reinforced Concrete Warehouse in Rijeka, Croatia
BuildingsDespite Croatia experiencing two strong earthquakes in 2020, Rijeka was not directly affected, underscoring the importance of proactive seismic assessment and strengthening in all seismic regions.
Berislav Bošnjak +2 more
doaj +1 more source
Journal of Oral Microbiology, 2019 Acetyl phosphate (AcP) is generally produced from acetyl coenzyme A by phosphotransacetylase (Pta), and subsequent reaction with ADP, catalyzed by acetate kinase (Ack), produces ATP.
Yasuo Yoshida +4 more
doaj +1 more source
Frontiers in Bioscience-Landmark, 2022 Fatty acid metabolism has attracted extensive attention for its key role in the occurrence and development of tumors. Fatty acids not only participate in the biosynthesis of phospholipids in the membrane to overcome the demand for rapidly proliferating ...
Hongdan Chen +5 more
doaj +1 more source
Electron Transfer Precedes ATP Hydrolysis during Nitrogenase Catalysis [PDF]
, 2013 The biological reduction of N2 to NH3 catalyzed by Mo-dependent nitrogenase requires at least eight rounds of a complex cycle of events associated with ATP-driven electron transfer (ET) from the Fe protein to the catalytic MoFe protein, with each ET ...
Antony, Edwin +7 more
core +2 more sources
Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells [PDF]
, 2017 ATP-sensitive potassium channels (K(ATP) channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, K(ATP) channels are essential for coupling glucose metabolism to insulin secretion.
Conway, Hannah +8 more
core +2 more sources
Journal of the American Chemical Society, 2019 Metal-organic frameworks (MOFs) are an emerging class of nanocarriers for drug delivery, owing to their tunable chemical functionality. Here we report ATP-responsive zeolitic imidazole framework-90 (ZIF-90) as a general platform for cytosolic protein ...
Xiaoti Yang +5 more
semanticscholar +1 more source
Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]
, 1987 Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger G. +18 more
core +1 more source