Results 41 to 50 of about 1,031,420 (245)
Біологічні студії, 2023 Background. Histamine is one of the versatile biogenic amines with multiple roles in the immune response and allergic disorders. Histamine and ATP can act as ligands in the body.
Nataliya Harasym +5 more
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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
Proceedings of the National Academy of Sciences of the United States of America, 2008 Lung cancers caused by activating mutations in the epidermal growth factor receptor (EGFR) are initially responsive to small molecule tyrosine kinase inhibitors (TKIs), but the efficacy of these agents is often limited because of the emergence of drug ...
C. Yun +7 more
semanticscholar +1 more source
BiologyFormoterol, a β2-adrenergic receptor (β2AR) agonist, shows promise in various diseases, but its effectiveness in Parkinson’s disease (PD) is debated, with unclear regulation of mitochondrial homeostasis.
Jui-Chih Chang +8 more
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The molecular mechanism of ATP synthesis by F1F0-ATP synthase
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2002 ATP synthesis by oxidative phosphorylation and photophosphorylation, catalyzed by F1F0-ATP synthase, is the fundamental means of cell energy production. Earlier mutagenesis studies had gone some way to describing the mechanism. More recently, several X-ray structures at atomic resolution have pictured the catalytic sites, and real-time video recordings
Alan E. Senior +2 more
openaire +3 more sources
Identification of an ATP-sensitive potassium channel in mitochondria
Nature, 2019 Mitochondria provide chemical energy for endoergonic reactions in the form of ATP, and their activity must meet cellular energy requirements, but the mechanisms that link organelle performance to ATP levels are poorly understood.
Angela Paggio +8 more
semanticscholar +1 more source
Closing a Key Gap in DSCSA Compliance with Credentialing
Blockchain in Healthcare Today, 2023 In this session, the Open Credentialing Initiative (OCI) introduces the concept and practical application of electronic credentials. The audience will learn about their use in the context of DSCSA and how they enable timely compliance with the DSCSA ...
Bob Celeste, David Kessler
doaj +1 more source
H+ Transport is an Integral Function of the Mitochondrial ADP/ATP Carrier
Nature, 2019 The mitochondrial ADP/ATP carrier (AAC) is a major transport protein of the inner mitochondrial membrane. It exchanges mitochondrial ATP for cytosolic ADP and controls cellular production of ATP.
A. Bertholet +12 more
semanticscholar +1 more source
A new electoral bottom-up model of institutional governance
Scientific ReportsThe sustainable governance of Global Risky Commons (GRC)—global commons in the presence of a sizable risk of overall failure—is ubiquitous and requires a global solution. A prominent example is the mitigation of the adverse effects of global warming.
Carlos M. Garrido +4 more
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Clinical Interventions in Aging, 2022 Yanfang Zhang, Lirong Gong, Yuan Zhang, Shuan Dong, Jia Shi, Xiangyun Li, Yan Guo, Simeng He, Xiaoyang Wu, Shasha Liu, Huayang Liu, Lantian Zhang, Jianbo Yu Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical
Zhang Y +12 more
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Structure, mechanism, and regulation of the chloroplast ATP synthase
Science, 2018 Protons find a path Adenosine triphosphate (ATP) synthases are dynamos that interconvert rotational and chemical energy. Capturing the complete structure of these multisubunit membrane-bound complexes has been hindered by their inherent ability to adopt ...
Alexander Hahn +4 more
semanticscholar +1 more source