Results 51 to 60 of about 1,031,420 (245)

Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The ATP synthase in the inner membrane of mitochondria generates most of the ATP that enables higher organisms to live. The inner membrane forms deep invaginations called cristae.
T. Blum   +4 more
semanticscholar   +1 more source

Cannabidiol (CBD) Upregulates Vitamin D3 Receptors (VDRs) Expression That Modulates Cytokines (TNF-α, IL-6), Tissue Elasticity, Cellular Senescence, and Mitochondrial ATP Generation in Human and Rodent Cell Lines

open access: yesNutrition and Dietary Supplements, 2023
Mahendra Kumar Trivedi,1 Alice Branton,1 Dahryn Trivedi,1 Sambhu Mondal,2 Snehasis Jana2 1Trivedi Global, Inc, Research & Development, Henderson, Nevada, USA; 2Trivedi Science Research Laboratory Pvt.
Trivedi MK   +4 more
doaj  

Evolution of uncontrolled proliferation and the angiogenic switch in cancer

open access: yesMathematical Biosciences and Engineering, 2012
The major goal of evolutionary oncology is to explain how malignant traits evolve to become cancer 'hallmarks.' One such hallmark---the angiogenic switch---is difficult to explain for the same reason altruism is difficult to explain. An angiogenic clone
John D. Nagy, Dieter Armbruster
doaj   +1 more source

Mechanisms of AMPK in the maintenance of ATP balance during energy metabolism

open access: yesCell Biology International, 2018
AMP‐activated protein kinase (AMPK) is a conserved sensor of cellular energy change and is activated by increased AMP/ATP and/or ADP/ATP ratios. AMPK maintains the energy balance by decreasing the ATP‐consuming processes such as transcription of ...
R. Ke   +4 more
semanticscholar   +1 more source

Changes in contractile characteristics of rat skeletal muscles associated with P2-receptor activation after spinal cord transection [PDF]

open access: yesАнналы клинической и экспериментальной неврологии
Introduction. Traumatic spinal cord and peripheral-nerve injury is associated with release of proinflammatory cytokines and chemokines, which may stimulate neuronal activity.
Adel E. Khairullin   +6 more
doaj   +1 more source

Persister formation in Staphylococcus aureus is associated with ATP depletion

open access: yesNature Microbiology, 2016
Persisters are dormant phenotypic variants of bacterial cells that are tolerant to killing by antibiotics1. Persisters are associated with chronic infections and antibiotic treatment failure1–3.
Brian P. Conlon   +9 more
semanticscholar   +1 more source

The motor of the ATP synthase

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1998
A model is presented in which ion translocation through the F0 part of the ATP synthase drives the rotation of the ring of c subunits (rotor) versus the a subunit (stator). The coupling ion binding sites on the rotor are accessible from the cytoplasm of a bacterial cell except for the c subunit at the interface to the stator.
Peter Dimroth   +2 more
openaire   +3 more sources

ATP signalling in epilepsy

open access: yesPurinergic Signalling, 2008
This paper focuses on a role for ATP neurotransmission and gliotransmission in the pathophysiology of epileptic seizures. ATP along with gap junctions propagates the glial calcium wave, which is an extraneuronal signalling pathway in the central nervous system.
Kumaria, A, Tolias, CM, Burnstock, G
openaire   +4 more sources

Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1

open access: yesScience, 2019
ATP production under lockdown Cellular processes must respond to change, often by speeding up, slowing down, or stopping altogether. Adenosine triphosphate (ATP) synthases use a transmembrane proton gradient to produce ATP, but this reaction can go in ...
Jinke Gu   +8 more
semanticscholar   +1 more source

Fondová schémata jako možná řešení finanční udržitelnosti dánského penzijního systému

open access: yesTrendy v podnikání, 2020
The financial sustainability of pension systems is one of the crucial topics in the context of population aging. The issue of financial sustainability is primarily associated with public unfunded pension schemes, where there is an increase in future ...
Jan Pokorný, Pavlína Hejduková
doaj   +1 more source

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