Results 61 to 70 of about 1,508,022 (243)
ATP mediates both activation and inhibition of K(ATP) channel activity via cAMP-dependent protein kinase in insulin-secreting cell lines. [PDF]
The single-channel recording technique was employed to investigate the mechanism conferring ATP sensitivity to a metabolite-sensitive K channel in insulin-secreting cells.
Ciani, S, Eddlestone, GT, Ribalet, B
core
Use of 31P magnetisation transfer magnetic resonance spectroscopy to measure ATP changes after 670 nm transcranial photobiomodulation in older adults [PDF]
Elizabeth J. Fear +7 more
openalex +1 more source
Background. Histamine is one of the versatile biogenic amines with multiple roles in the immune response and allergic disorders. Histamine and ATP can act as ligands in the body.
Nataliya Harasym +5 more
doaj +1 more source
Yanfang Zhang, Lirong Gong, Yuan Zhang, Shuan Dong, Jia Shi, Xiangyun Li, Yan Guo, Simeng He, Xiaoyang Wu, Shasha Liu, Huayang Liu, Lantian Zhang, Jianbo Yu Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical
Zhang Y +12 more
doaj
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall +5 more
doaj +1 more source
Extracellular ATP drives systemic inflammation, tissue damage and mortality [PDF]
Systemic inflammatory response syndromes (SIRS) may be caused by both infectious and sterile insults, such as trauma, ischemia-reperfusion or burns. They are characterized by early excessive inflammatory cytokine production and the endogenous release of ...
Brouckaert, Peter +4 more
core +1 more source
ATP Hydrolysis by α‐Synuclein Amyloids is Mediated by Enclosing β‐Strand
Pathological amyloids have been considered chemically inert until recently. Here it is shown that α‐synuclein amyloids catalyze the hydrolysis of the universal energy molecule, ATP. The cryo‐EM structure of the complex reveals an additional β‐strand (purple) that encloses the ATP‐binding site. Within the cavity, several lysine residues are required for
Lukas Frey +6 more
wiley +1 more source
Host Translational Control by Stress Granules Promotes Mycobacterium tuberculosis Pathogenesis
During Mycobacterium tuberculosis infection, stress granules (SGs) formed in macrophages sequester key signaling and metabolic regulators such as mTORC1 components (mTOR, Raptor) and mitochondrial complex I subunits (Ndufa12), leading to suppressed cap‐dependent translation, reduced mitochondrial activity, and impaired innate immune responses.
Jaewhan Kim +9 more
wiley +1 more source
Method of detecting and counting bacteria in body fluids [PDF]
A novel method is reported for determining bacterial levels in urine samples, which method depends on the quantitative determination of bacterial adenosine triphosphate (ATP) in the presence of non-bacterial ATP.
Chappelle, E. W., Picciolo, G. L.
core +1 more source
Both pharmacological blockade and genetic knockdown of astrocytic connexin43 channels in the preBötzinger complex induce a high‐frequency breathing pattern, thereby enhancing respiratory motor output. This effect is mediated by astrocytic activation and subsequent ATP release, which activates P2Y1 receptors on somatostatin‐expressing preBötzinger ...
Xue Zhao +11 more
wiley +1 more source

