Results 61 to 70 of about 1,767,276 (258)
Abstract The left ventricle (LV) is the primary pumping chamber of the heart, generating high systolic pressure to sustain systemic circulation. LV contractile dysfunction is a hallmark of various cardiovascular diseases and is associated with mitochondrial dysfunction, characterised by decreased oxidative phosphorylation (OXPHOS) capacity and ...
Tingting Fang +3 more
wiley +1 more source
Structural Basis for the Catalytic Mechanism of ATP‐Dependent Diazotase CmaA6
Several diazotases have been reported in recent years, but the detailed catalytic mechanism is unclear. From X‐ray crystallography and Cryo‐EM analysis, we obtained the structure of a diazotase CmaA6, which synthesizes 3‐diazocoumaric acid. Kinetic analysis and computational analysis indicated that CmaA6 catalyzes diazotization via an unprecedented ...
Seiji Kawai +5 more
wiley +2 more sources
A new electoral bottom-up model of institutional governance
The sustainable governance of Global Risky Commons (GRC)—global commons in the presence of a sizable risk of overall failure—is ubiquitous and requires a global solution. A prominent example is the mitigation of the adverse effects of global warming.
Carlos M. Garrido +4 more
doaj +1 more source
Jón the Fleming: Low German in Thirteenth-Century Norway and Fourteenth-Century Iceland [PDF]
Low German influence is one of the most prominent characteristics of Old Norse in the later medieval period, but the processes whereby this took place are little evidenced.
Hall, ATP
core
Maximizing efficiency of rumen microbial protein production. [PDF]
Rumen microbes produce cellular protein inefficiently partly because they do not direct all ATP toward growth. They direct some ATP toward maintenance functions, as long-recognized, but they also direct ATP toward reserve carbohydrate synthesis and ...
Andries +158 more
core +2 more sources
ATP‐Responsive and ATP‐Fueled Self‐Assembling Systems and Materials
Adenosine triphosphate (ATP) is a central metabolite that plays an indispensable role in various cellular processes, from energy supply to cell‐to‐cell signaling.
Jie Deng, A. Walther
semanticscholar +1 more source
Neurobiology of mitochondrial dynamics in sleep
Abstract figure legend In neurons, variations in sleep history are accompanied by alterations in mitochondrial dynamics, including changes in size, fission and fusion events, the emergence of extra‐large and ‘hourglass’‐shaped mitochondria, mitophagy, and modifications in intracristal space volume and in the number of contact sites between mitochondria
Raffaele Sarnataro
wiley +1 more source
Mechanisms of AMPK in the maintenance of ATP balance during energy metabolism
AMP‐activated protein kinase (AMPK) is a conserved sensor of cellular energy change and is activated by increased AMP/ATP and/or ADP/ATP ratios. AMPK maintains the energy balance by decreasing the ATP‐consuming processes such as transcription of ...
R. Ke +4 more
semanticscholar +1 more source
Closing a Key Gap in DSCSA Compliance with Credentialing
In this session, the Open Credentialing Initiative (OCI) introduces the concept and practical application of electronic credentials. The audience will learn about their use in the context of DSCSA and how they enable timely compliance with the DSCSA ...
Bob Celeste, David Kessler
doaj +1 more source
Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows
Significance The ATP synthase in the inner membrane of mitochondria generates most of the ATP that enables higher organisms to live. The inner membrane forms deep invaginations called cristae.
T. Blum +4 more
semanticscholar +1 more source

