Results 131 to 140 of about 27,747 (231)

Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective

The FEBS Journal, Volume 293, Issue 6, Page 1801-1817, March 2026.
Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska, Anna Koczurowska, Marta Orlikowska, Maciej Nielipinski, Dominika Nielipinska, Bartosz Sekula   +5 more
wiley   +1 more source

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Mechanism of ATP-binding Cassette Transporter A1-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles*

Journal of Biological Chemistry, 2007
Charulatha Vedhachalam, P. Duong, M. Nickel, David V. Nguyen, P. Dhanasekaran, H. Saito, G. Rothblat, S. Lund‐Katz, M. Phillips   +8 more
semanticscholar   +1 more source

Elucidating the Genetic Basis of Columnar Upright Architecture in Populus Through CRISPR Disruption of TILLER ANGLE CONTROL1

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1377-1397, March 2026.
ABSTRACT Narrow or upright branch angles in shoots and leaves lead to columnar, upright‐growing tree architectures, as observed in various tree species such as Lombardy poplar (Populus nigra var. italica). However, the genetic mechanism underlying this unique growth habit in Lombardy poplar has not yet been elucidated.
Na‐Young Choi, Min‐Ha Kim, Hyun‐A Jang, Seung‐Won Pyo, Kong‐Young Park, Hyoshin Lee, Eun‐Kyung Bae, Jae‐Heung Ko   +7 more
wiley   +1 more source

MicroRNA-144 Regulates Hepatic ATP Binding Cassette Transporter A1 and Plasma High-Density Lipoprotein After Activation of the Nuclear Receptor Farnesoid X Receptor

Circulation Research, 2013
T. Q. de Aguiar Vallim, E. Tarling, Tammy Kim, M. Civelek, Á. Baldán, Christine Esau, P. Edwards   +6 more
semanticscholar   +1 more source

Regulation of ATP-binding cassette transporter A1 in cholesteryl ester storage disease

, 2009
Previous studies from the Francis laboratory have determined that regulation of ABCA1 expression is impaired in the lysosomal cholesterol storage disorder Niemann-Pick type C (NPC) disease, the presumed reason for the low plasma HDL-cholesterol (HDL-C) levels found in the majority of NPC disease patients.
openaire   +1 more source

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1

Arteriosclerosis, Thrombosis and Vascular Biology, 2011
C. Ramírez, A. Dávalos, L. Goedeke, A. Salerno, Nikhil Warrier, D. Cirera-Salinas, Y. Suárez, C. Fernández‐Hernando   +7 more
semanticscholar   +1 more source

Lipopolysaccharide Down Regulates Both Scavenger Receptor B1 and ATP Binding Cassette Transporter A1 in RAW Cells

Infection and Immunity, 2002
I. Baranova, T. Vishnyakova, A. Bocharov, Zhigang Chen, A. Remaley, J. Stonik, T. Eggerman, A. Patterson   +7 more
semanticscholar   +1 more source

Nomenclature for Factors of the HLA System, 2026

HLA, Volume 107, Issue 3, March 2026.
Steven G. E. Marsh, Kazutoyo Osoegawa, Walter F. Bodmer, Ronald E. Bontrop, Mary N. Carrington, Henry A. Erlich, Sebastiaan Heidt, Rhonda Holdsworth, Wolfgang R. Mayr, Martin Maiers, Peter Parham, Effie W. Petersdorf, James Robinson, John Trowsdale, Marcelo Fernández‐Viña   +14 more
wiley   +1 more source

The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux. [PDF]

J Cell Mol Med, 2019
Lien CC, Chen CH, Lee YM, Guo BC, Cheng LC, Pan CC, Shyue SK, Lee TS.   +7 more
europepmc   +1 more source