Results 121 to 130 of about 1,912,571 (214)

Snapshots of the maltose transporter during ATP hydrolysis

, 2011
ATP-binding cassette transporters are powered by ATP, but the mechanism by which these transporters hydrolyze ATP is unclear. In this study, four crystal structures of the full-length wild-type maltose transporter, stabilized by adenosine 5′-
Michael L. Oldham, Jue Chen
core   +1 more source

Sphingosine 1-phosphate receptor 1 signaling in macrophages reduces atherosclerosis in LDL receptor–deficient mice

JCI Insight
Sphingosine 1-phosphate (S1P) is a lysosphingolipid with antiatherogenic properties, but mechanisms underlying its effects remain unclear. We here investigated atherosclerosis development in cholesterol-rich diet–fed LDL receptor–deficient mice with high
Francesco Potì, Enrica Scalera, Renata Feuerborn, Josephine Fischer, Lilli Arndt, Georg Varga, Evangelia Pardali, Matthias D. Seidl, Manfred Fobker, Gerhard Liebisch, Bettina Hesse, Alexander H. Lukasz, Jan Rossaint, Beate E. Kehrel, Frank Rosenbauer, Thomas Renné, Christina Christoffersen, Manuela Simoni, Ralph Burkhardt, Jerzy-Roch Nofer   +19 more
doaj   +1 more source

Cholesterol Accumulation Enhances Cigarette Smoke-Induced Airway Epithelial Inflammation

International Journal of COPD
Du Jing,1,2 Jin-Kang Yu,1 Hai-Pin Chen,1 Ling-Ling Dong,1 Wen Li,1 Zhou-Yang Li,1 Jie-Sen Zhou1 1Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ...
Jing D, Yu JK, Chen HP, Dong LL, Li W, Li ZY, Zhou JS   +6 more
doaj  

Microglial Immunometabolic Remodeling After Ischemic Stroke: The Interplay Between Mitochondrial Stress and the Ischemic Microenvironment. [PDF]

Transl Stroke Res
Liu C, Liu Q, Jing W, Liu L, Wei L, Li X, Du X.   +6 more
europepmc   +1 more source

Colchicine enhances macrophage cholesterol efflux by targeting DTL-mediated ubiquitination and degradation of ABCA1. [PDF]

RMD Open
Tong L, Wu W, Wang Y, Duan L, Li H.
europepmc   +1 more source

Expression of ABCB1, ABCB5, and ABCG2 Transporters in Human Renal Cell Carcinoma and Their Underlying Signaling Pathways. [PDF]

Curr Issues Mol Biol
Vass A, Király J, Szabó E, Kónya G, Shammas A, Szegedi K, Dezső B, Juhász É, Halmos G, Szabó Z.   +9 more
europepmc   +1 more source

Cholesterol Metabolism in Cancer Patients: Mechanisms, Treatment-Related Effects, and Cardio-Oncology Management. [PDF]

Oncol Res
Piscione M, Pala B, Cribari F, Gualtieri P, Gaudio D, Perrone MA, Di Renzo L.   +6 more
europepmc   +1 more source

Chemoproteomic profiling of adaptive ATP-binding protein activity in <i>Enterococcus faecium</i> in response to host-derived cues. [PDF]

FEMS Microbes
Grunnvåg JS, Hegstad K, Dela Ahator S, Lentz CS.   +3 more
europepmc   +1 more source

Potential Roles of Flavonoids from Chrysanthemi Flos and Chrysanthemi Indici Flos in Modulating Bile Acid Metabolism: Mechanistic Insights and Future Perspectives. [PDF]

Int J Mol Sci
Zhao S, Zeng L, Tang H, Cui Y, Zeng R, Xie J.   +5 more
europepmc   +1 more source

ABCA1 as a Gatekeeper of Pancreatic β-Cell Cholesterol Homeostasis: Links Between Lipoprotein Stress, Lipotoxicity, and Insulin Secretion. [PDF]

Nutrients
Fukunaga K, Kobayashi T, Saheki T, Yoshimura T, Jiang W, Zhang H, Ly R, Kumano M, Yamashita A, Imachi H, Murao K.   +10 more
europepmc   +1 more source