Results 1 to 10 of about 15,107 (221)

Cellular Localization and Trafficking of the Human ABCG1 Transporter [PDF]

Biology, 2014
We have developed a suitable heterologous cell expression system to study the localization, trafficking, and site(s) of function of the human ABCG1 transporter.
Christian A Combs, Daniela Malide, Alan Remaley   +2 more
exaly   +5 more sources

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity [PDF]

Nature Communications, 2015
ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a mediator of tumour immunity.
Duygu Sag, ÇaĞlar ÇekİÇ, Joel Linden   +2 more
exaly   +8 more sources

Diets containing sea cucumber (Isostichopus badionotus) meals are hypocholesterolemic in young rats [PDF]

PLOS ONE, 2013
Peer reviewedPublisher ...
A Venkateswaran, Alberto Davalos, AO Odegaard, AS Greenberg, AV Khera, BA Janowski, C Zetina Moguel, CD Mathers, DE Kleiner, DJ Gordon, DP Mertz, ER Mojica, FR Van der Leij, G Grant, George Grant, GJ Miller, H Komano, H Leontowicz, HA Tyroler, HH Liu, Hirian Alonso Moshe Barrera-Perez, I Hawa, J Ayo, J Folch, J Lin, J Wen, JC Cohen, JC Cohen, JC Yoon, JD Horton, Jean-Marc A Lobaccaro, JJ Repa, Jorge Montero, Jorge Rubio-Piña, JR Schultz, JW Heinecke, JY Chiang, K Liu, KJ Livak, L Olivera, Leticia Olivera-Castillo, M Yahyavi, MC Damiani, MD Säemann, ME Rodríguez, MF Lopes-Virella, Miguel Angel Olvera-Novoa, N Hasegawa, N Torres, NE Miller, Nina Valadez-Gonzalez, P Araujo, P Lefebvre, Pablo Acereto-Escoffie, RG Herrmann, RK Semple, Roche Diagnostics, Rossanna Rodriguez-Canul, RR Sokal, S Acton, S Najwa, T Park, T Rajamohan, T Sugawara, VL Roger, Víctor Ceja-Moreno, X Duan, X Hu, XQ Hu, XQ Hu, Y Zhong, Yasser Chim-Chi, Z Hossain   +72 more
core   +16 more sources

Ex Vivo Characterization of Peritoneal Macrophages from Novel ABCA1-LSL and ABCG1-LSL Mice for Macrophage-Specific ABC-Transporter Overexpression [PDF]

Biology
We aimed to characterize peritoneal macrophages from two novel mouse models that enable macrophage-specific overexpression of ABCA1 and ABCG1 via Cre recombinase.
Jing Echesabal-Chen, Lawrence Fernando, Ally Brawner, Achala Pokhrel, Kun Huang, Rhonda Reigers Powell, Terri Bruce, Jan Guz, Fu-Lei Tang, Alexander Awgulewitsch, Alexis Stamatikos   +10 more
doaj   +2 more sources

Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells

Frontiers in Oncology, 2018
The ATP-binding cassette transporter G1 (ABCG1) is a cholesterol lipid efflux pump whose role in tumor growth has been largely unknown. Our transcriptomics revealed that ABCG1 was powerfully expressed in rapidly metastatic, aggregative colon cancer cells,
Chiharu Sogawa, Stuart Calderwood, Kisho Ono   +2 more
exaly   +3 more sources

Genome-wide association study identifies ABCG1 as a susceptibility locus for tick-borne encephalitis [PDF]

iScience
Summary: Tick-borne encephalitis (TBE) is a viral infection of the central nervous system, caused by the tick-borne encephalitis virus (TBEV) presenting clinically as meningitis, meningoencephalitis, and meningoencephalomyelitis.
Piyush G. Gampawar, Manfred G. Sagmeister, Daniel Růžek, Nina A. Schweintzger, Edith Hofer, Benno Kohlmaier, Vendula Švendová, Petra Bogovič, Joanna M. Zajkowska, Lenka Krbková, Věra Štruncová, Auksė Mickienė, Daniela S. Kohlfürst, Astrid Sonnleitner, Andrea Fořtová, Michaela Berankova, Martina Pychova, Dace Zavadska, Neneh Sallah, Alexander Pichler, Dalibor Sedláček, Aleš Chrdle, Christoph Haudum, Barbara Obermayer-Pietsch, Per Hoffmann, Markus M. Nöthen, Mari-Liis Tammesoo, Andres Metspalu, Petr Husa, Karin Stiasny, Alexander Binder, Andrea Berghold, Franc Strle, Martin L. Hibberd, Werner Zenz   +34 more
doaj   +2 more sources

The Effect of Eight Weeks of Aquatic Aerobic Training on ABCA1 and ABCG1 Genes Expression in the Blood Mononuclear Cells in Women After Coronary Artery Bypass Grafting [PDF]

Journal of Kerman University of Medical Sciences, 2020
Background: The aim of this research was to investigate the effect of aquatic aerobic training on regulatory factors related to Reverse Cholesterol Transport in women after coronary artery bypass grafting (CABG).
Mahdiyeh Haj Hosseini, Amir Rashidlamir, Mahtab Moazzami, Mansoor Moazenzadeh   +3 more
doaj   +1 more source

Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function. [PDF]

PLoS ONE, 2018
The ABC transporter ABCG1 contributes to the regulation of cholesterol efflux from cells and to the distribution of cholesterol within cells. We showed previously that ABCG1 deficiency inhibits insulin secretion by pancreatic beta cells and, based on its
Megan T Harris, Syed Saad Hussain, Candice M Inouye, Anna M Castle, J David Castle   +4 more
doaj   +1 more source

Protein kinase A modulates the activity of a major human isoform of ABCG1

Journal of Lipid Research, 2012
ABCG1 is an ABC half-transporter that exports cholesterol from cells to HDL. This study set out to investigate differences in posttranslational processing of two human ABCG1 protein isoforms, termed ABCG1(+12) and ABCG1(− 12), that differ by the presence
Ingrid C. Gelissen, Laura J. Sharpe, Cecilia Sandoval, Geetha Rao, Maaike Kockx, Leonard Kritharides, Wendy Jessup, Andrew J. Brown   +7 more
doaj   +1 more source

Utilizing the LoxP-Stop-LoxP System to Control Transgenic ABC-Transporter Expression In Vitro

Biomolecules, 2022
ABCA1 and ABCG1 are two ABC-transporters well-recognized to promote the efflux of cholesterol to apoAI and HDL, respectively. As these two ABC-transporters are critical to cholesterol metabolism, several studies have assessed the impact of ABCA1 and ...
Ikechukwu Esobi, Olanrewaju Oladosu, Jing Echesabal-Chen, Alexis Stamatikos   +3 more
doaj   +1 more source