Medical Laboratory Journal, 2021 Background and objectives: Cardiovascular disease is one of the most important causes of mortality worldwide. The present study aimed to compare two different cardiac rehabilitation protocols on ATP-binding cassette sub-family G member 1 (ABCG1 ...
Rokhsareh Moosavi +3 more
doaj
The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release [PDF]
, 2013 <p>Objectives: Macrophages are central to the inflammatory processes driving rheumatoid arthritis (RA) synovitis. The molecular pathways that are induced in synovial macrophages and thereby promote RA disease pathology remain poorly understood.</
Ananth +42 more
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ABCG1: How critical for cholesterol transport? [PDF]
Cell Metabolism, 2005 In the current issue of Cell Metabolism, Kennedy et al. (2005) have extended our understanding of the ABCG1 transporter. Their studies demonstrate that, at least in macrophages, ABCG1 is responsible for much of the cholesterol efflux that utilizes mature HDL as an acceptor.
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Resveratrol modulates ATPase activity of liposome‐reconstituted ABCG1 [PDF]
FEBS Letters, 2013 ABCG1 is a half‐sized transporter with an unquestionable importance in cholesterol homeostasis. So far, its expression and thus its activity was suggested to be regulated at transcriptional level by LXR and PPAR agonists including polyphenols. However, it is unknown whether there are other mechanisms of up‐regulation of ABCG1 activity.
Athayde Moncorvo Collado, Alejandro de +4 more
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High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation [PDF]
, 2018 Recent evidence suggests that oxidative stress can play a role in the pathogenesis and the progression of prostate cancer (PCa). Reactive oxygen species (ROS) generation is higher in PCa cells compared to normal prostate epithelial cells and this ...
Botta, Margherita +8 more
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The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64) in BRIN-BD11 insulinoma cells [PDF]
, 2016 No abstract ...
Borges Pinto, Joana, Graham, Annette
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Loss of ABCG1 Results in Chronic Pulmonary Inflammation [PDF]
The Journal of Immunology, 2008 Abstract ABCG1, a member of the ATP-binding cassette transporter superfamily, is highly expressed in multiple cells of the lung. Loss of ABCG1 results in severe pulmonary lipidosis in mice, with massive deposition of cholesterol in both alveolar macrophages and type 2 cells and the accumulation of excessive surfactant phospholipids ...
Angel, Baldán +3 more
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ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin[S]
Journal of Lipid Research, 2013 ATP-binding cassette protein G1 (ABCG1) is important for the formation of HDL. However, the biochemical properties of ABCG1 have not been reported, and the mechanism of how ABCG1 is involved in HDL formation remains unclear. We established a procedure to
Hiroshi Hirayama +4 more
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ABCG1 rs57137919G>a polymorphism is functionally associated with varying gene expression and apoptosis of macrophages. [PDF]
PLoS ONE, 2014 ATP-binding cassette transporter G1 (ABCG1) is a transmembrane cholesterol transporter involved in macrophage sterol homeostasis, reverse cholesterol transport (RCT), and atherosclerosis.
Fang Liu +6 more
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Validation of suitable internal control genes for expression studies in aging. [PDF]
, 2009 Quantitative data from experiments of gene expression are often normalized through levels of housekeeping genes transcription by assuming that expression of these genes is highly uniform. This practice is being questioned as it becomes increasingly clear
Bacalini, MARIA GIULIA +9 more
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