Results 31 to 40 of about 11,132 (198)
The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments [PDF]
, 2017 The ATP-binding cassette sub-family G member 1 (ABCG1) exports cellular cholesterol to high-density lipoproteins (HDL). However, a number of recent studies have suggested ABCG1 is predominantly localised to intracellular membranes.
Ingrid C. Gelissen +15 more
core +1 more source
Is Two out of Three Enough for ABCG1? [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Macrophages have the right tools to synthesize all the free cholesterol they need. If macrophages also could degrade cholesterol when they have too much, the concept of in vivo reverse cholesterol transport (RCT) would be irrelevant. Fortunately for those of us who do research in this area, the ability of macrophages to closely regulate their cellular ...
openaire +2 more sources
Medical Laboratory Journal, 2021 Background and objectives: Cardiovascular disease is one of the most important causes of mortality worldwide. The present study aimed to compare two different cardiac rehabilitation protocols on ATP-binding cassette sub-family G member 1 (ABCG1 ...
Rokhsareh Moosavi +3 more
doaj
Loss of ABCG1 Results in Chronic Pulmonary Inflammation [PDF]
The Journal of Immunology, 2008 Abstract ABCG1, a member of the ATP-binding cassette transporter superfamily, is highly expressed in multiple cells of the lung. Loss of ABCG1 results in severe pulmonary lipidosis in mice, with massive deposition of cholesterol in both alveolar macrophages and type 2 cells and the accumulation of excessive surfactant phospholipids ...
Angel, Baldán +3 more
openaire +2 more sources
BLAST results for TRINITY_DN86437_c0_g1_i16.p1 with ABCG1 orthologs.
, 2023 BLAST results for TRINITY_DN86437_c0_g1_i16.p1 with ABCG1 orthologs.
Alejandro Sanchez-Flores (207232) +5 more
core +1 more source
Insight Into ABCG1-Mediated Cholesterol Efflux [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Macrophages in the arterial intima take up modified LDL and become cholesterol-ester laden foam cells, which are the primary cell type in newly formed fatty streak lesions, and which play an important role throughout lesion progression and plaque vulnerability.
openaire +2 more sources
ABCG1-mediated generation of extracellular cholesterol microdomains [PDF]
Journal of Lipid Research, 2014 Previous studies have demonstrated that the ATP-binding cassette transporters (ABC)A1 and ABCG1 function in many aspects of cholesterol efflux from macrophages. In this current study, we continued our investigation of extracellular cholesterol microdomains that form during enrichment of macrophages with cholesterol.
Sebastian R. Freeman +7 more
openaire +3 more sources
Posttranslational Modification Cross-Talk in Vascular Cells: Molecular Mechanisms and Therapeutic Implications for Atherosclerosis. [PDF]
Cell Biochem FunctABSTRACT Atherosclerosis is driven by coordinated changes in endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs). Post‐translational modifications (PTMs), phosphorylation, acetylation, ubiquitination, SUMOylation, O‐GlcNAcylation, palmitoylation, ISGylation, and ADP‐ribosylation, integrate metabolic, inflammatory, and ...
Jiang W, Du H.
europepmc +2 more sources
ABCG1 as a potential oncogene in lung cancer
Experimental and Therapeutic Medicine, 2017 ATP-binding cassette transporter G1 (ABCG1) is a member of the ABC transporter family and regulates cellular cholesterol homeostasis. It has important roles in cholesterol homeostasis and tumor immunity, which has, however, not been reported in lung cancer. The present study showed that ABCG1 protein is upregulated in lung cancer compared with adjacent
Tian, Chunyan +5 more
openaire +3 more sources
Supplementary data for 'Adrenal Abcg1 controls cholesterol flux and steroidogenesis'.
, 2023 Cholesterol is the precursor of all steroids, but how cholesterol flux is controlled in steroidogenic tissues is poorly understood. The cholesterol exporter ABCG1 is an essential component of the reverse cholesterol pathway and its systemic inactivation ...
Jani Liimatta (17121861) +9 more
core +1 more source