Results 161 to 170 of about 1,912,571 (214)
Interaction Between Microglial Lipid Droplet Metabolism and Immune Polarisation After Stroke: Mechanisms and Therapeutic Prospects. [PDF]
Yang J +8 more
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Repurposed cAMP-Modulating Agents Enhance 5-Fluorouracil Response Through Membrane-Dependent Mechanisms. [PDF]
Ribeiro E, Vale N.
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The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma. [PDF]
Maphutha J +5 more
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ATP-binding cassette transporter G1 and lipid homeostasis
Current Opinion in Lipidology, 2006This review briefly discusses the ATP-binding cassette transporter G (ABCG) family members and emphasizes recent studies that identify ABCG1 as a key regulator of cellular lipid homeostasis.The in-vivo importance of ABCG1 has recently been demonstrated with both loss-of-function and gain-of-function studies in mice.
Angel, Baldán +3 more
openaire +2 more sources
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2023
Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy, and it often leads to adverse pregnancy outcomes and seriously harms the health of mothers and infants. ATP-binding cassette transporter G1 (ABCG1) plays critical roles in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport.
Sixu, Liu +10 more
openaire +2 more sources
Gestational diabetes mellitus (GDM) is the most common metabolic disorder in pregnancy, and it often leads to adverse pregnancy outcomes and seriously harms the health of mothers and infants. ATP-binding cassette transporter G1 (ABCG1) plays critical roles in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport.
Sixu, Liu +10 more
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2013
ATP-binding cassette transporter G1 (ABCG1) mediates cholesterol efflux onto lipidated apolipoprotein A-I and HDL and plays a role in various important physiological functions. However, the mechanism by which ABCG1 mediates cholesterol translocation is unclear. Protein palmitoylation regulates many functions of proteins such as ABCA1.
Hong-mei, Gu +4 more
openaire +2 more sources
ATP-binding cassette transporter G1 (ABCG1) mediates cholesterol efflux onto lipidated apolipoprotein A-I and HDL and plays a role in various important physiological functions. However, the mechanism by which ABCG1 mediates cholesterol translocation is unclear. Protein palmitoylation regulates many functions of proteins such as ABCA1.
Hong-mei, Gu +4 more
openaire +2 more sources
Caveolin-1 and ATP Binding Cassette Transporter A1 and G1-Mediated Cholesterol Efflux
Cardiovascular & Hematological Disorders-Drug Targets, 2014Atherosclerosis is one major cause of cardiovascular diseases, the leading cause of death in industrialized countries. Reverse cholesterol transport (RCT) is thought to be one primary pathway to protect against atherosclerosis. The first and rate-limiting step of RCT is ATP-binding cassette transport A1 (ABCA1) and ABCG1-mediated cholesterol efflux ...
Faqi, Wang, Hong-mei, Gu, Da-wei, Zhang
openaire +2 more sources
Pancreas, 2012
Adenosine triphosphate-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) are 2 important cholesterol transporters in human pancreatic β-cells. The aim of this study was to investigate their alteration in insulinomas and their potential associations with abnormal insulin secretion in these patients.Six patients with insulinoma and 6 healthy ...
Huali, Zhou +6 more
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Adenosine triphosphate-binding cassette transporter A1 (ABCA1) and G1 (ABCG1) are 2 important cholesterol transporters in human pancreatic β-cells. The aim of this study was to investigate their alteration in insulinomas and their potential associations with abnormal insulin secretion in these patients.Six patients with insulinoma and 6 healthy ...
Huali, Zhou +6 more
openaire +2 more sources
ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose
Diabetes Research and Clinical Practice, 2013ATP binding cassette transporter G1 (ABCG1), a regulator of cholesterol efflux to HDL, has been shown to decrease in macrophages and smooth muscle cells under high glucose conditions. Endothelial cells have a high capacity to efflux sterols and express ABCG1.
Jiahong, Xue +3 more
openaire +2 more sources

