Results 181 to 190 of about 1,912,571 (214)

3β,5α,6β-Cholestanetriol and 25-hydroxycholesterol accumulate in ATP-binding cassette transporter G1 (ABCG1)-deficiency

Atherosclerosis, 2014
Oxysterols are oxidized derivatives of sterols that have cytotoxic effects and are potent regulators of diverse cellular functions. Efficient oxysterol removal by the sub-family G member 1 of the ATP-binding cassette transporters (ABCG1) is essential for cell survival and control of cellular processes.
Thomas, Engel, Manfred, Fobker, Jana, Buchmann, Frank, Kannenberg, Stephan, Rust, Jerzy-Roch, Nofer, Annette, Schürmann, Udo, Seedorf   +7 more
openaire   +2 more sources

ATP‐binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

The FASEB Journal, 2007
Transporters in the ABCG family appear to be involved in the cellular excretion of cholesterol and other sterols in a cell‐ and tissue‐specific fashion. Overexpression of ATP‐binding cassette transporters G1 (Abcgl) and G4 (Abcg4) can promote cellular cholesterol efflux to high‐density lipoprotein (HDL), but the
Wang, Nan, Yvan-Charvet, Laurent, Lütjohann, Dieter, Mulder, Monique, Vanmierlo, Tim, Kim, Tae-Wan, Tall, Alan R   +6 more
openaire   +3 more sources

ATP-Binding Cassette Transporters A1 and G1, HDL Metabolism, Cholesterol Efflux, and Inflammation: Important Targets for the Treatment of Atherosclerosis

Current Drug Targets, 2011
Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol deposition in arteries. Plasma high density lipoprotein (HDL) levels bear a strong independent inverse relationship with atherosclerotic cardiovascular disease. One central antiatherogenic role of HDL is believed to be its ability to remove excessive peripheral ...
Dan, Ye, Bart, Lammers, Ying, Zhao, Illiana, Meurs, T J, Van Berkel, Miranda, Van Eck   +5 more
openaire   +2 more sources

Gonadotropin-releasing hormone regulates atp-binding cassette g1 and g4 to transport cholesterol in the brain

2017
The ATP-binding cassette (ABC) transporter family G1 and G4 play an important role in the transport of lipids, especially cholesterol across cell membranes in the brain. Gonadotropin-releasing hormone (GnRH), which is widely known to be the driving force in reproduction, has been implied to play other roles apart from its direct involvement in the ...
openaire   +1 more source

Investigating a role for the ATP-binding cassette transporters A1 and G1 during synaptic remodeling in the adult mouse

2007
This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
openaire   +1 more source

[Endothelial dysfunction induced by high glucose is associated with decreased ATP-binding cassette transporter G1 expression].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2013
To investigate the role of ATP-binding cassette transporter G1 (ABCG1) in endothelial dysfunction induced by high glucose.Human aortic endothelial cells (HAECs) were incubated in the presence of 5.6 or 30 mmol/L glucose for 24-72 h with or without a 2-h pretreatment with the LXR agonist 22(R)-hydroxycholesterol.
Jiahong, Xue, Xiaolin, Niu, Jin, Wei, Xin, Dong, Canzhan, Zhu, Yinhu, Dang, Anqi, Song, Huimei, Huang   +7 more
openaire   +1 more source

ATP Binding Cassette Transporter G1 Is a Negative Regulator of Pulmonary Innate Immunity.

A15. PULMONARY INFECTIONS: MODULATING HOST DEFENSES, 2009
DW Draper, JH Madenspacher, LM DeGraff, MB Fessler   +3 more
openaire   +1 more source

Role of ATP-Binding Cassette Transporters A1 and G1 in Reverse Cholesterol Transport and Atherosclerosis

2014
Makoto Ayaori, Katsunori Ikewaki
openaire   +1 more source

Role of ATP-Binding Cassette Transporters A1 and G1 in Reverse Cholesterol Transport and Atherosclerosis

2017
Kazuhiro Nakaya, Makoto Ayaori, Katsunori Ikewaki   +2 more
openaire   +1 more source

The Cholesterol Transporter ATP Binding Cassette G1 Regulates Allergen-Induced Pulmonary Inflammation

C36. CRITICAL PATHWAYS IN ALLERGIC INFLAMMATION, 2011
David W. Draper, Rhonda H. Wilson, Gregory S. Whitehead, Hideki Nakano, Jennifer H. Madenspacher, Alan Remaley, Donald N. Cook, Michael B. Fessler   +7 more
openaire   +1 more source