Results 11 to 20 of about 191,822 (304)

Subunit a of ATP synthase – essential for ATP synthase dimerization in Saccharomyces cerevisiae [PDF]

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018
Katarzyna Niedźwiecka, Emilia Baranowska, Chiranjit Panja, Róża Kucharczyk   +3 more
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Design, Synthesis,and Biological Evaluation of Mono-and Diamino-Substituted Squaramide Derivatives as Potent Inhibitorsof Mycobacterial Adenosine Triphosphate (ATP) Synthase [PDF]

J Med Chem
Paul R. Palme, Shipra Grover, Rana Abdelaziz, Lea Mann, Andreas M. Kany, Lina Ouologuem, Karin Bartel, Lindsay Sonnenkalb, Norbert Reiling, Anna K. H. Hirsch, Dirk Schnappinger, John L. Rubinstein, Peter Imming, Adrian Richter   +13 more
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Targeting the ATP synthase in bacterial and fungal pathogens: beyond Mycobacterium tuberculosis

Journal of Global Antimicrobial Resistance, 2022
: The ATP synthase is a multicomponent enzyme that is largely conserved across the kingdoms of life. In many species the ATP synthase is central in the synthesis of ATP by using the electrochemical proton gradient generated via the electron transport ...
Martin Vestergaard, Dirk Bald, Hanne Ingmer   +2 more
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Autoantibodies to endothelial cell surface ATP synthase, the endogenous receptor for hsp60, might play a pathogenic role in vasculatides. [PDF]

PLoS ONE, 2011
BACKGROUND: Heat shock protein (hsp) 60 that provides "danger signal" binds to the surface of resting endothelial cells (EC) but its receptor has not yet been characterized. In mitochondria, hsp60 specifically associates with adenosine triphosphate (ATP)
Jean-Eric Alard, Sophie Hillion, Loïc Guillevin, Alain Saraux, Jacques-Olivier Pers, Pierre Youinou, Christophe Jamin   +6 more
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Targeting the ATP Synthase in Staphylococcus aureus Small Colony Variants, Streptococcus pyogenes and Pathogenic Fungi

Antibiotics, 2021
The ATP synthase has been validated as a druggable target with the approval of the ATP synthase inhibitor, bedaquiline, for treatment of drug-resistant Mycobacterium tuberculosis, a bacterial species in which the ATP synthase is essential for viability ...
Martin Vestergaard, Sahar Roshanak, Hanne Ingmer   +2 more
doaj   +1 more source

IF1 promotes oligomeric assemblies of sluggish ATP synthase and outlines the heterogeneity of the mitochondrial membrane potential

Communications Biology, 2023
The coexistence of two pools of ATP synthase in mitochondria has been largely neglected despite in vitro indications for the existence of reversible active/inactive state transitions in the F1-domain of the enzyme.
Inés Romero-Carramiñana, Pau B. Esparza-Moltó, Sonia Domínguez-Zorita, Cristina Nuevo-Tapioles, José M. Cuezva   +4 more
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Inhibitors of ATP Synthase as New Antibacterial Candidates

Antibiotics, 2023
ATP, the power of all cellular functions, is constantly used and produced by cells. The enzyme called ATP synthase is the energy factory in all cells, which produces ATP by adding inorganic phosphate (Pi) to ADP.
Rawan Mackieh, Nadia Al-Bakkar, Milena Kfoury, Rabih Roufayel, Jean-Marc Sabatier, Ziad Fajloun   +5 more
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ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast

Scientific Reports, 2023
The mitochondrial ATP synthase, an enzyme that synthesizes ATP and is involved in the formation of the mitochondrial mega-channel and permeability transition, is a multi-subunit complex. In S.
Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska, Roza Kucharczyk   +4 more
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Human F1F0 ATP synthase, mitochondrial ultrastructure and OXPHOS impairment: a (super-)complex matter? [PDF]

PLoS ONE, 2013
Mitochondrial morphogenesis is a key process of cell physiology. It is essential for the proper function of this double membrane-delimited organelle, as it ensures the packing of the inner membrane in a very ordered pattern called cristae.
Johann Habersetzer, Isabelle Larrieu, Muriel Priault, Bénédicte Salin, Rodrigue Rossignol, Daniel Brèthes, Patrick Paumard   +6 more
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Mitochondrial F-ATP Synthase Co-Migrating Proteins and Ca²⁺-Dependent Formation of Large Channels

Cells, 2023
Monomers, dimers, and individual FOF1-ATP synthase subunits are, presumably, involved in the formation of the mitochondrial permeability transition pore (PTP), whose molecular structure, however, is still unknown.
Anna B. Nikiforova, Yulia L. Baburina, Marina P. Borisova, Alexey K. Surin, Ekaterina S. Kharechkina, Olga V. Krestinina, Maria Y. Suvorina, Svetlana A. Kruglova, Alexey G. Kruglov   +8 more
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