Results 31 to 40 of about 329,086 (345)

Structures and proton-pumping strategies of mitochondrial respiratory enzymes [PDF]

, 2001
Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the ...
Chan, Sunney I., Schultz, Brian E.
core   +1 more source

Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth. [PDF]

PLoS ONE, 2015
We examined the thymoquinone induced inhibition of purified F1 or membrane bound F1FO E. coli ATP synthase. Both purified F1 and membrane bound F1FO were completely inhibited by thymoquinone with no residual ATPase activity. The process of inhibition was
Zulfiqar Ahmad, Thomas F Laughlin, Ismail O Kady   +2 more
doaj   +1 more source

Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth

Cell Reports, 2022
Summary: Invaginations of the mitochondrial inner membrane, termed cristae, are hubs for oxidative phosphorylation. The mitochondrial contact site and cristae organizing system (MICOS) and the dimeric F1Fo-ATP synthase play important roles in controlling
Heike Rampelt, Florian Wollweber, Mariya Licheva, Rinse de Boer, Inge Perschil, Liesa Steidle, Thomas Becker, Maria Bohnert, Ida van der Klei, Claudine Kraft, Martin van der Laan, Nikolaus Pfanner   +11 more
doaj   +1 more source

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations [PDF]

, 2004
CBS domains are defined as sequence motifs that occur in several different proteins in all kingdoms of life. Although thought to be regulatory, their exact functions have been unknown.
Anis, Miliea, Green, Kevin A., Hardie, D. Grahame, Hawley, Simon A., Norman, David G., Scott, John W., Scullion, Gillian A., Stewart, Greg   +7 more
core   +6 more sources

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller, A Kemp Jr, A Shevchenko, AA Starkov, AL Goldstein, Andrea M. Hunt, B Cooper, B Guerin, B Hoffmann, B Kucejova, Beata Torocsik, C Chinopoulos, C Chinopoulos, C Janke, C Konrad, C Konrad, Christos Chinopoulos, CP Smith, Cynthia L. David, D De Stefani, DJ Pagliarini, F Jiang, G Arselin, G Brandolin, G Szabadkai, G Woldegiorgis, George Tsaprailis, GJ Lauquin, H Aquila, I Amigo, J Clegg, J Laco, J Traba, J Traba, JA Reynolds, JE Kokoszka, Jeffrey L. Brodsky, JJ Lemasters, JK Eng, JM Baughman, K Beyer, Karoly Vekey, KE Kwast, Lilla Turiak, M Bonora, M Klingenberg, M Rak, M Rey, MA Menze, Monika Wysocka-Kapcinska, NL Andon, NN Zheleznova, O Ozohanics, PJ Henderson, R Craig, R Kramer, R Parvin, RA Haworth, RD Gietz, RK Emaus, Roza Kucharczyk, S Cavero, S Manon, S Uribe, SC Hand, T Hamazaki, TM Rickey, UK Laemmli, V Giorgio, Vera Adam-Vizi, WJ Qian, XJ Chen   +71 more
core   +8 more sources

GaMF1.39’s antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876

Microbiology Spectrum, 2023
The Mycobacterium tuberculosis (Mtb) F-ATP synthase generates most of the biological energy currency ATP. Previously, we identified the mycobacterium-specific loop of the F-ATP synthase subunit γ as a new anti-tuberculosis target and discovered the novel
Priya Ragunathan, Pearly Shuyi Ng, Samsher Singh, Wee Han Poh, Dennis Litty, Nitin Pal Kalia, Simon Larsson, Amaravadhi Harikishore, Scott A. Rice, Philip W. Ingham, Volker Müller, Garrett Moraski, Marvin J. Miller, Thomas Dick, Kevin Pethe, Gerhard Grüber   +15 more
doaj   +1 more source

A minimal mathematical model of nonphotochemical quenching of chlorophyll fluorescence [PDF]

, 2010
Copyright © 2010 Elsevier Ireland Ltd.
Ebenhöh, Oliver, Houwaart, Torsten, Lokstein, Heiko, Schlede, Stephanie, Tirok, Katrin   +4 more
core   +1 more source

Assembling the mitochondrial ATP synthase [PDF]

Proceedings of the National Academy of Sciences, 2018
Mitochondria are known as the powerhouses of the cell. The F1Fo-ATP synthase of the mitochondrial inner membrane produces the bulk of cellular ATP. The respiratory chain complexes pump protons across the inner membrane into the intermembrane space and thereby generate a proton-motive force that drives the ATP synthase.
Jiyao Song, Nikolaus Pfanner, Thomas Becker   +2 more
openaire   +3 more sources

Visualizing mitochondrial FoF1-ATP synthase as the target of the immunomodulatory drug Bz-423

, 2018
Targeting the mitochondrial enzyme FoF1-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases. The immuno-modulatory compound Bz-423 is such a drug that binds to subunit
Börsch, Michael, Glick, Gary D., Starke, Ilka   +2 more
core   +1 more source

Structure, Regulation, and Significance of Cyanobacterial and Chloroplast Adenosine Triphosphate Synthase in the Adaptability of Oxygenic Photosynthetic Organisms

Microorganisms
In cyanobacteria and chloroplasts (in algae and plants), ATP synthase plays a pivotal role as a photosynthetic membrane complex responsible for producing ATP from adenosine diphosphate and inorganic phosphate, utilizing a proton motive force gradient ...
Siyan Yi, Xin Guo, Wenjing Lou, Shaoming Mao, Guodong Luan, Xuefeng Lu   +5 more
doaj   +1 more source