Results 41 to 50 of about 837,065 (393)
Molecules, 2023 Polyphenols have attracted attention in the fight against antibiotic-resistant bacteria, as they show antibacterial action. Considering that polyphenols inhibit F1Fo-ATP synthase (ATP synthase) and that bacteria need a constant energy production to ...
Silvia Ravera +4 more
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Current Biology, 2021 Biological processes in all living cells are powered by ATP, a nearly universal molecule of energy transfer. ATP synthases produce ATP utilizing proton gradients that are usually generated by either respiration or photosynthesis.
K. Song +6 more
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ATP synthase: Evolution, energetics, and membrane interactions [PDF]
The Journal of General Physiology, 2020 This review outlines a holistic framework for studying ATP synthase and emphasizes the importance of considering interactions with the lipid environment in shaping the function and evolutionary history of membrane proteins.
Jasmine A. Nirody +2 more
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Assembly of F1F0-ATP synthases
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2015 F1F0-ATP synthases are multimeric protein complexes and common prerequisites for their correct assembly are (i) provision of subunits in appropriate relative amounts, (ii) coordination of membrane insertion and (iii) avoidance of assembly intermediates that uncouple the proton gradient or wastefully hydrolyse ATP.
Dario Leister, Thilo Rühle
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36 degree step size of proton-driven c-ring rotation in FoF1-ATP synthase [PDF]
, 2009 Synthesis of the biological "energy currency molecule" adenosine triphosphate ATP is accomplished by FoF1-ATP synthase. In the plasma membrane of Escherichia coli, proton-driven rotation of a ring of 10 c subunits in the Fo motor powers catalysis in the ...
Boersch, Michael +6 more
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The rotary mechanism of the ATP synthase [PDF]
Archives of Biochemistry and Biophysics, 2008 The F0F1 ATP synthase is a large complex of at least 22 subunits, more than half of which are in the membranous F0 sector. This nearly ubiquitous transporter is responsible for the majority of ATP synthesis in oxidative and photo-phosphorylation, and its overall structure and mechanism have remained conserved throughout evolution. Most examples utilize
Marwan K. Al-Shawi +2 more
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Cell Death and Disease, 2023 ATPase Inhibitory Factor 1 (IF1) regulates the activity of mitochondrial ATP synthase. The expression of IF1 in differentiated human and mouse cells is highly variable.
Sonia Domínguez-Zorita +9 more
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Cryo-EM structures provide insight into how E. coli F1Fo ATP synthase accommodates symmetry mismatch
Nature Communications, 2020 F1Fo ATP synthase functions as a biological rotary generator that makes a major contribution to cellular energy production. It comprises two molecular motors coupled together by a central and a peripheral stalk. Proton flow through the Fo motor generates
M. Sobti +7 more
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Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The oxidation of energy rich compounds generates a proton motive force, a chemical potential difference for protons, across the inner membranes of the mitochondria.
J. Carroll +4 more
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EMBO reports, 2000 All living species use ATP as a general source of energy by hydrolysing it into ADP and phosphate. In most species the regeneration of this vital molecule is catalysed by the H+-transporting F1F0 ATP synthases, marvellous machines that couple the flow of protons down an electrochemical gradient to form ATP from ADP and phosphate.
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