Results 71 to 80 of about 25,762 (279)

CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.

Journal of the American Society of Nephrology, 2020
Sequence and copy number variations in the human CFHR-Factor H gene cluster comprising the complement genes CFHR1, CFHR2, CFHR3, CFHR4, CFHR5, and Factor H are linked to the human kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 ...
P. Zipfel, T. Wiech, E. Stea, C. Skerka
semanticscholar   +1 more source

Pregnancy-triggered atypical hemolytic uremic syndrome (aHUS): a Global aHUS Registry analysis

JN. Journal of Nephrology (Milano. 1992), 2021
Atypical hemolytic uremic syndrome (aHUS) is a rare disease in which uncontrolled terminal complement activation leads to systemic thrombotic microangiopathy (TMA).
F. Fakhouri, M. Scully, G. Ardissino, I. Al-Dakkak, Benjamin Miller, E. Rondeau   +5 more
semanticscholar   +1 more source

Case Series of 3 Patients Diagnosed With Atypical Hemolytic Uremic Syndrome Successfully Treated With Steroids, Plasmapheresis, and Rituximab

Canadian Journal of Kidney Health and Disease, 2017
Rationale: Atypical hemolytic uremic syndrome, which has a high probability of chronic kidney disease, morbidity, and mortality, needs to be promptly recognized when patients present with microangiopathic hemolysis.
Jeffery M. Patterson, Lauren Bolster, Loree Larratt   +2 more
doaj   +1 more source

Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease

Thrombosis Journal, 2019
Background Atypical hemolytic uremic syndrome is a rare group of disorders that have in common underlying complement amplifying conditions. These conditions can accelerate complement activation that results in a positive feedback cycle.
Ramy M. Hanna, Noah Merin, Richard M. Burwick, Lama Abdelnour, Umut Selamet, Beshoy Yanny, Patrick Bui, Mary Fouad, Ira Kurtz   +8 more
doaj   +1 more source

HUS and atypical HUS [PDF]

, 2017
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by intravascular hemolysis, thrombocytopenia, and acute kidney failure. HUS is usually categorized as typical, caused by Shiga toxin-producing Escherichia coli (STEC) infection,
Al-Nouri, Allen, Amaral, Ardissino, Arvidsson, Atefi, Atkinson, Berry, Bhakdi, Bhattacharjee, Boltax, Brady, Bresin, Bruneau, Bu, Caires, Campistol, Canalejo, Carson, Chapin, Chien, Cofiell, Cole, Conway, Conway, Coppo, Cornec-Le Gall, de Córdoba, Del Conde, Delvaeye, Dempsey, Devine, Dhakal, Dragon-Durey, Egbor, El-Husseini, Faguer, Fakhouri, Ferreira, Ferreira, Fremeaux-Bacchi, Frimat, George, Gilbert, Gorsuch, Gottschalk, Grabowski, Greenbaum, Hill, Hornung, Hosler, Huber-Lang, Hughson, Hyvärinen, Iida, Ikeda, Jin, Jokiranta, Kang, Karnchanaphanurach, Karpman, Karpman, Karpman, Kavanagh, Keir, Kielstein, Kim, Kourouklaris, Krisinger, Kronbichler, Laurence, Law, Lechner, Lehtinen, Lemaire, Licht, Liszewski, Loirat, Lupu, Manuelian, Martel, Mathew, Matsukuma, Mele, Meri, Morton, Moskovich, Mukhopadhyay, Nakakuma, Nester, Noris, Noris, Noris, Oikonomopoulou, Orth-Höller, Ozaki, Pangburn, Pangburn, Pape, Pecoraro, Pilzer, Podack, Ricklin, Rinder, Rodríguez-Pintó, Roumenina, Ruggenenti, Schutte, Scully, Sethi, Sims, Sinha, Song, Ståhl, Ståhl, Sung, Szilágyi, T. Sakari Jokiranta, Tawadrous, Tedesco, Thomas, Thurman, Toh, Tsai, Tufano, Vasu, Ward, Warwicker, Wehling, Wetsel, Whaley, Wiedmer, Wig, Woodworth, Zipfel, Zipfel   +135 more
core   +1 more source

Baseline characteristics and evolution of Brazilian patients with atypical hemolytic uremic syndrome: first report of the Brazilian aHUS Registry

Clinical Kidney Journal, 2022
Background Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare disease. Therefore, studies involving large samples are scarce, making registries powerful tools to evaluate cases. We present herein the first analysis of the Brazilian aHUS Registry (
M. Vaisbich, Luís Gustavo Modelli de Andrade, Precil Diego Miranda de Menezes Neves, L. Palma, M. C. D. de Castro, Cassiano Augusto Braga Silva, Maria Izabel Neves de Holanda Barbosa, M. Penido, Oreste Angelo Ferra Neto, R. Sobral, S. M. Miranda, Stanley de Almeida Araújo, I. Pietrobom, H. Takase, C. Ribeiro, Rafael Marques da Silva, César Augusto Almeida de Carvalho, D. Machado, Ana Mateus Simões Teixeira E Silva, A. da Silva, E. R. Russo, Flávio Henrique Soares Barros, J. C. Nasserala, L. S. C. de Oliveira, Lucimary de Castro Sylvestre, Rafael Weissheimer, Sueli de Oliveira Nascimento, Gilson Bianchini, Fellype de Carvalho Barreto, V. Veloso, P. Fortes, V. Colares, J. G. Gomes, André Falcão Pedrosa Leite, Pablo Girardelli Mendonça Mesquita, O. M. Vieira-Neto   +35 more
semanticscholar   +1 more source

Atypical Hemolytic Uremic Syndrome Occurring After Receipt of mRNA-1273 COVID-19 Vaccine Booster: A Case Report

American Journal of Kidney Diseases, 2022
Atypical hemolytic uremic syndrome (aHUS) is a subtype of thrombotic microangiopathy (TMA) characterized by a dysregulation of the alternative complement pathway.
K. Claes, I. Geerts, W. Lemahieu, A. Wilmer, D. Kuypers, P. Koshy, S. Ombelet   +6 more
semanticscholar   +1 more source

Thrombotic microangiopathies: thrombotic thrombocytopenic purpura / hemolytic uremic syndrome [PDF]

, 2010
Thrombotic microangiopathies (TMAs) are pathological conditions characterized by generalized microvascular occlusion by platelet thrombi, thrombocytopenia, and microangiopathic hemolytic anemia.
Mastroianni Kirsztajn, Gianna, Polito, Maria Goretti   +1 more
core   +2 more sources

Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland [PDF]

, 2017
Factor H autoantibodies can impair complement regulation, resulting in atypical hemolytic uremic syndrome, predominantly in childhood. There are no trials investigating treatment, and clinical practice is only informed by retrospective cohort ...
Almond, M, Awan, A, Booth, C, Brocklebank, V, Finlay, E, Fitzpatrick, M, Gilbert, RD, Goodship, TH, Hegde, S, Inward, C, Johnson, S, Kaur, A, Kavanagh, D, Kerecuk, L, Kinoshita, M, Marchbank, KJ, Marks, SD, Salama, AD, Sheerin, NS, Sheerin, TP, Tyerman, K, Walsh, PR, Webb, N, Wong, EKS   +23 more
core   +1 more source

Acute ST-Segment Elevation Myocardial Infarction as Initial Presentation of Atypical Hemolytic-Uremic Syndrome

JACC: Case Reports, 2021
A young woman presented with an acute ST-segment elevation myocardial infarction. Her clinical course was complicated by cardiogenic shock and acute renal failure. Work-up revealed thrombocytopenia and hemolytic anemia.
Edward Chau, MD, MS, Shiqian Li, MD, Peter Z. Xu, MD, Grace X. Li, MD, Wesley Ghasem, MD, Ilene C. Weitz, MD, Brittney K. DeClerck, MD, Eugene C. DePasquale, MD, Bassam Yaghmour, MD   +8 more
doaj   +1 more source