Results 21 to 30 of about 8,556 (213)
Eculizumab in Atypical Hemolytic–Uremic Syndrome [PDF]
New England Journal of Medicine, 2013 To the Editor: With regard to the article by Legendre et al. (June 6 issue)(1): assessment of the 37 patients with atypical hemolytic-uremic syndrome is difficult, since the process of selection seems opaque, particularly for the 20 patients in trial 2.
Christophe M, Legendre +2 more
openaire +8 more sources
Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome
Brazilian Journal of Nephrology, 2020 Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Diana Carolina Bello-Marquez +3 more
doaj +2 more sources
Brazilian Journal of Nephrology, 2020 Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure.
John Fredy Nieto-Rios +7 more
doaj +2 more sources
Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report
Онкогематология, 2021 Atypical hemolytic uremic syndrome is a rare disorder uncontrolled complement activation, which is classically manifested by anemia, thrombocytopenia and renal failure.
A. Yu. Smirnova +4 more
doaj +1 more source
Atypical Hemolytic Uremic Syndrome
Pediatric Clinics of North America, 2018 Atypical hemolytic uremic syndrome is a rare life-threatening disease of unregulated complement activation. Untreated, the prognosis is generally poor; more than one-half of patients die or develop end-stage renal disease within 1 year. Atypical hemolytic uremic syndrome is characterized by thrombotic microangiopathy with evidence of hemolysis ...
Bradley P. Dixon, Ralph A. Gruppo
+7 more sources
Influenza B-Associated Atypical Hemolytic Uremic Syndrome [PDF]
Revista Portuguesa de Nefrologia e Hipertensão, 2022 Hemolytic uremic syndrome (HUS) triggered by influenza virus (iHUS) is rare. Influenza A infections have been described to trigger atypical HUS (aHUS) in individuals with an underlying genetic complement dysregulation. To date there are only few reports
Lia Mano +5 more
doaj +1 more source
Journal of Medical Case Reports, 2021 Background Cardiac and neurological involvement in hemolytic uremic syndrome are life-threatening complications. The most frequent complications of cardiac involvement in hemolytic uremic syndrome are myocarditis and cardiac dysfunction due to fluid ...
Sophie Mounier +5 more
doaj +1 more source
Transplantation in Atypical Hemolytic Uremic Syndrome [PDF]
Seminars in Thrombosis and Hemostasis, 2010 Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by overactivation of complement. Recurrence following renal transplantation is determined by a genetic predisposition. Genetic screening of all individuals with aHUS should be performed prior to listing for transplantation. Individuals with isolated mutations in MCP have a low risk of
Kavanagh D +3 more
openaire +3 more sources
Медицинская иммунология, 2020 This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina +5 more
doaj +1 more source
Haematologica, 2017 Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of excess activation of the alternative pathway of complement that are treated with eculizumab, a humanized monoclonal antibody against the terminal complement ...
Xuan Yuan +8 more
doaj +1 more source