Results 21 to 30 of about 12,655 (217)

Clostridioides difficile-Associated Atypical Hemolytic-Uremic Syndrome Successfully Treated With Eculizumab: A Case Report and Literature Review

Critical Care Explorations, 2021
BACKGROUND:. Clostridioides difficile infection is a rare precipitant for patients to develop atypical hemolytic-uremic syndrome, of which the pathogenesis remains unclear. Previous reports suggest activation of cytokine storm from binding of cyotoxins A
Michael N. Moulton, DO, Carl L. Kay, MD, Joshua T. Romain, MD, Benjamin D. Morrow, MD, Gilda M. Bobele, MD   +4 more
doaj   +1 more source

Hemolytic Uremic Syndrome: A Case Report

Journal of Nepal Medical Association, 2023
Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any body organ leading to thrombocytopenia, coombs-negative hemolytic anemia, and end-organ damage.
Sandesh Gaire, Mandira Shrestha, Chaitanya Darshan Bhattarai, Susajjan Dhungana, Surakshya Gyawali, Arun Bajgain   +5 more
doaj   +1 more source

Case series: coronavirus disease 2019 infection as a precipitant of atypical hemolytic uremic syndrome: two case reports

Journal of Medical Case Reports, 2021
Background Atypical hemolytic uremic syndrome is an exceedingly rare thrombotic microangiopathy caused by accelerated activation of the alternative complement pathway.
Christine J. Kurian, Zachary French, Patrick Kukulich, Matthew Lankiewicz, Sushil Ghimire, Omar H. Maarouf, Sanaa Rizk, Ruben Rhoades   +7 more
doaj   +1 more source

Atypical Hemolytic Uremic Syndrome [PDF]

Seminars in Nephrology, 2013
Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease characterized by complement overactivation. Inherited defects in complement genes and acquired autoantibodies against complement regulatory proteins have been described.
Kavanagh D, Goodship TH, Richards A
openaire   +3 more sources

A novel missense mutation in complement factor I predisposes patients to atypical hemolytic uremic syndrome: a case report

Journal of Medical Case Reports, 2022
Background Atypical hemolytic uremic syndrome, also called the nondiarrheal form of hemolytic uremic syndrome, is a rare disease characterized by the triad of thrombocytopenia, Coomb’s test-negative microangiopathic hemolytic anemia, and acute renal ...
Xin Wei, Juan Li, Xiaojiang Zhan, Luxia Tu, Haowen Huang, Ying Wang   +5 more
doaj   +1 more source

Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

Brazilian Journal of Nephrology, 2020
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Diana Carolina Bello-Marquez, John Fredy Nieto-Rios, Lina Maria Serna-Higuita, Alfonso Jose Gonzalez-Vergara   +3 more
doaj   +2 more sources

Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli in a renal transplant recipient case report

Brazilian Journal of Nephrology, 2020
Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure.
John Fredy Nieto-Rios, Monica Zuluaga-Quintero, Julio Cesar Valencia-Maturana, Diana Carolina Bello-Marquez, Arbey Aristizabal-Alzate, Gustavo Adolfo Zuluaga-Valencia, Lina Maria Serna-Higuita, Luis Fernando Arias   +7 more
doaj   +2 more sources

Atypical Hemolytic Uremic Syndrome

Pediatric Clinics of North America, 2018
Atypical hemolytic uremic syndrome is a rare life-threatening disease of unregulated complement activation. Untreated, the prognosis is generally poor; more than one-half of patients die or develop end-stage renal disease within 1 year. Atypical hemolytic uremic syndrome is characterized by thrombotic microangiopathy with evidence of hemolysis ...
Bradley P. Dixon, Ralph A. Gruppo
  +7 more sources

Influenza B-Associated Atypical Hemolytic Uremic Syndrome [PDF]

Revista Portuguesa de Nefrologia e Hipertensão, 2022
Hemolytic uremic syndrome (HUS) triggered by influenza virus (iHUS) is rare. Influenza A infections have been described to trigger atypical HUS (aHUS) in individuals with an underlying genetic complement dysregulation. To date there are only few reports
Lia Mano, Telma Francisco, Joana Gaspar, Gabriela Pereira, Raquel Santos, Margarida Abranches   +5 more
doaj   +1 more source

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice [PDF]

, 2019
Atypical hemolytic uremic syndrome (aHUS) is frequently associated in humans with loss-of-function mutations in complement-regulating proteins or gain-of-function mutations in complement-activating proteins.
Atkinson, John P, Barlow, Paul N, Cook, H. T, Cooke, Katie, Denton, Harriet, Kavanagh, David, Liszewski, M. K, Marchbank, Kevin J, Pappworth, Isabel Y, Pickering, Matthew C, Smith-Jackson, Kate, Yang, Yi   +11 more
core   +3 more sources