Results 61 to 70 of about 12,655 (217)

Complement regulator CD46: Genetic variants and disease associations [PDF]

, 2015
Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement.
Atkinson, John P, Liszewski, M. Kathryn
core   +2 more sources

Complete Dialysis‐Free Recovery From Severe Malaria–Associated Acute Kidney Injury and Multiorgan Failure: A Case Report and Brief Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Severe malaria remains a major cause of acute kidney injury and multiorgan failure in endemic regions, often requiring renal replacement therapy. However, access to dialysis is limited in many resource‐constrained settings, making outcomes highly dependent on early diagnosis and effective antimalarial treatment. We report a 32‐year‐old man who
Tamirat Godebo Woyimo, Amare Hailu Ashine, Mohammed Kedir Shukri, Yonas Damtew Bejiga, Ragasa Getachew, Yosef Bekele Bonsa, Rediet Girmaye, Tsion Haile Woldemariam, Adugna Lamessa   +8 more
wiley   +1 more source

The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease [PDF]

, 2015
Atypical hemolytic uremic syndrome (aHUS) is characterized by complement attack against host cells due to mutations in complement proteins or autoantibodies against complement factor H (CFH).
Abarrategui-Garrido, Adams, Adrian Goldman, Arnab Bhattacharjee, Baker, Barbara Uzonyi, Bhattacharjee, Bhattacharjee, Blanc, Blaum, Castiblanco-Valencia, Dragon-Durey, Dragon-Durey, Dragon-Durey, Emsley, Eszter Trojnár, Eyler, Ferreira, Freddo, Fritzler, Goicoechea de Jorge, Harald Seeberger, Hebecker, Heinen, Herbert, Herbert, Hofer, Holmes, Jokiranta, Józsi, Józsi, Józsi, Kabsch, Kajander, Lehtinen, Manuelian, McCarthy, McCoy, Meri, Mihály Józsi, Moore, Morgan, Noris, Oppermann, Pangburn, Robert Kolodziejczyk, Roumenina, Satu Hyvärinen, Sinha, Stefanie Reuter, Strobel, Strobel, Sánchez-Corral, Sánchez-Corral, T. Sakari Jokiranta, Venables, Zipfel, Zipfel, Zoltán Prohászka, Ágnes Szilágyi   +59 more
core   +1 more source

Pathogenesis of Atypical Hemolytic Uremic Syndrome

Journal of Atherosclerosis and Thrombosis, 2019
Atypical hemolytic uremic syndrome (aHUS) is a type of thrombotic microangiopathy (TMA) defined by thrombocytopenia, microangiopathic hemolytic anemia, and renal failure. aHUS is caused by uncontrolled complement activation in the alternative pathway (AP).
Yoshida, Yoko, Kato, Hideki, Ikeda, Yoichiro, Nangaku, Masaomi   +3 more
openaire   +3 more sources

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co‐Infection: A Case Report and Comprehensive Literature Review

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha, Bistrit Dahal, Anamika Adhikari, Kushal Singh Basnet, Shivaditya Singh, Manaswi Acharya   +5 more
wiley   +1 more source

Complement activation in atypical hemolytic uremic syndrome and scleroderma renal crisis: a critical analysis of pathophysiology

Brazilian Journal of Nephrology, 2018
Scleroderma is an autoimmune disease that affects multiple systems. While pathophysiologic mechanisms governing the development of scleroderma are relatively poorly understood, advances in our understanding of the complement system are clarifying the ...
Roman Zuckerman, Arif Asif, Eric J. Costanzo, Tushar Vachharajani   +3 more
doaj   +1 more source

Síndrome Hemolítico Urémico Atípico en Cuidados Intensivos: Caso Clínico de un Adulto [PDF]

, 2016
info:eu-repo/semantics ...
Agudo, I, Azevedo, L, Bento, L, Cavaco, R, Germano, N, Souto-Moura, T   +5 more
core   +1 more source

MULTIFACTORIAL ETIOLOGY OF ATIPICAL HEMOLYTIC UREMIC SYNDROME-CASE REPORT [PDF]

Sanamed
Introduction: Hemolytic uremic syndromes are characterized by the simultaneous occurrence of hemolytic anemia, microangiopathy, thrombocytopenia, and acute renal insufficiency.
Skoric Jasmina, Klacar Uzelac Marija, Kostic Ana   +2 more
doaj   +1 more source

COVID-19 vaccination and Atypical hemolytic uremic syndrome

Frontiers in Immunology, 2022
IntroductionCOVID-19 vaccination has been associated with rare but severe complications characterized by thrombosis and thrombocytopenia.Methods and ResultsHere we present three patients who developed de novo or relapse atypical hemolytic uremic syndrome
Romy N. Bouwmeester, Esther M.G. Bormans, Caroline Duineveld, Arjan D. van Zuilen, Anne-Els van de Logt, Jack F.M. Wetzels, Nicole C.A.J. van de Kar   +6 more
doaj   +1 more source

Eculizumab for Gemcitabine-Induced Hemolytic Uremic Syndrome: A Novel Therapy for an Emerging Condition [PDF]

, 2015
Introduction Atypical hemolytic uremic syndrome (aHUS), a thrombotic microangiopathy (TMA), is a disease characterized by hemolytic anemia, thrombocytopenia, and renal impairment. Gemcitabine, a commonly used chemotherapy, is emerging as a cause of aHUS.
Karkowsky, MD, Raphael, Parikh, MD, Kinjal   +1 more
core   +2 more sources