Results 11 to 20 of about 590,699 (329)

Atypical parkinsonism: An Update. [PDF]

Current Opinion in Neurology, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +8 more sources

Plasma Metabolite Markers of Parkinson's Disease and Atypical Parkinsonism. [PDF]

Metabolites, 2021
Differentiating between Parkinson’s disease (PD) and the atypical Parkinsonian disorders of multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) is difficult clinically due to overlapping symptomatology, especially at early disease ...
Pathan M, Wu J, Lakso HÅ, Forsgren L, Öhman A.   +4 more
europepmc   +8 more sources

Atypical parkinsonism can be a presenting feature of late‐onset Huntington's disease [PDF]

Clinical Case Reports, 2022
Huntington's disease is a progressive neurodegenerative disease that typically manifests with Choreic movements, psychological disorders, and cognitive decline. Some patients can initially present atypical movements other than the usual symptoms, such as
Mehri Salari, Nahid Beladi Moghadam, Sevim Soleimani, Masoud Etemadifar   +3 more
doaj   +2 more sources

Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins [PDF]

, 2016
The retromer complex acts as a scaffold for endosomal protein complexes that sort integral membrane proteins to various cellular destinations. The retromer complex is a heterotrimer of VPS29, VPS35, and VPS26.
Adam P. Jellett, Arighi, Balana, Bean, Bean, Brett M. Collins, Burd, Cai, Chan, Chapin, Chris M. Danson, Cullen, Damseh, Frances C. Tilley, Freeman, Gallon, Gomez, Gustavsson, Harbour, Harbour, Hesketh, Ian McGough, Joubert, Kate J. Heesom, Kerr, Kevin A. Wilkinson, Kirsty J. McMillan, Lauffer, MacLeod, Matthew Gallon, McGough, McGough, Muhammad, Peter J. Cullen, Phillips-Krawczak, Popoff, Rovelet-Lecrux, Seaman, Seaman, Seaman, Seaman, Shannon, Shi, Small, Steinberg, Steinberg, Temkin, Thomas Clairfeuille, Vardarajan, Vilariño-Güell, Vilariño-Güell, Wang, Yoshimura, Zavodszky, Zimprich   +54 more
core   +5 more sources

Pain in neurodegenerative diseases with atypical parkinsonism: a systematic review on prevalence, clinical presentation, and findings from experimental studies

Journal of Integrative Neuroscience, 2021
Parkinson’s disease-related pain has increasingly been investigated in research studies. Still, only a few studies have addressed the prevalence and clinical characteristics of pain in neurodegenerative disorders with atypical parkinsonism.
Jerry Yi Chang, Katarina Rukavina, Timothy Lawn, K Ray Chaudhuri   +3 more
doaj   +2 more sources

Novel SLC9A6 Variation in Female Carriers With Intellectual Disability and Atypical Parkinsonism. [PDF]

Neurol Genet, 2022
Background and Objectives Variations in SLC9A6 cause the X-linked neurologic disorder Christianson syndrome in males. Meanwhile, female carriers with SLC9A6 variations may remain asymptomatic or develop intellectual disability, behavioral problems, and ...
Nan H, Kim YJ, Tsuchiya M, Ishida A, Haro H, Hiraide M, Ohtsuka T, Takiyama Y.   +7 more
europepmc   +2 more sources

Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation [PDF]

Redox Biology, 2018
Sporadic cases account for 90–95% of all patients with Parkinson's Disease (PD). Atypical Parkinsonism comprises approximately 20% of all patients with parkinsonism. Progressive Supranuclear Palsy (PSP) belongs to the atypical parkinsonian diseases and
Plamena R. Angelova, Mario Barilani, Christopher Lovejoy, Marta Dossena, Mariele Viganò, Agostino Seresini, Daniela Piga, Sonia Gandhi, Gianni Pezzoli, Andrey Y. Abramov, Lorenza Lazzari   +10 more
doaj   +4 more sources

Effectiveness of an Inpatient Movement Disorders Program for Patients with Atypical Parkinsonism [PDF]

Parkinson's Disease, 2012
This paper investigated the effectiveness of an inpatient movement disorders program for patients with atypical parkinsonism, who typically respond poorly to pharmacologic intervention and are challenging to rehabilitate as outpatients.
Anna D. Hohler, Jyeming M. Tsao, Douglas I. Katz, T. Joy DiPiero, Christina L. Hehl, Alissa Leonard, Valerie Allen, Maura Gardner, Heidi Phenix, Marie Saint-Hilaire, Terry Ellis   +10 more
doaj   +2 more sources

MYORG -related disease is associated with central pontine calcifications and atypical parkinsonism [PDF]

Neurology: Genetics, 2020
Objective To identify the phenotypic, neuroimaging, and genotype-phenotype expression of MYORG mutations. Methods Using next-generation sequencing, we screened 86 patients with primary familial brain calcification (PFBC) from 60 families with autosomal ...
Viorica Chelban, Miryam Carecchio, Gillian Rea, Abdalla Bowirrat, Salman Kirmani, Luca Magistrelli, Stéphanie Efthymiou, Lucía Schottlaender, Jana Vandrovcová, Vincenzo Salpietro, Ettore Salsano, Davide Pareyson, Luisa Chiapparini, Farida Jan, Shahnaz Ibrahim, Fatima Khan, Zul Qarnain, Stanislav Groppa, Nin Bajaj, Bettina Balint, Kailash P. Bhatia, Andrew J. Lees, Patrick J. Morrison, Nicholas Wood, Barbara Garavaglia, Henry Houlden   +25 more
openalex   +2 more sources

Atypical parkinsonism and self‐mutilation: A new lens on the old concept [PDF]

Clinical Case Reports, 2021
We report a case of atypical parkinsonism and self‐mutilation.
Mehri Salari, Masoud Etemadifar, Kimia Ghanbari   +2 more
doaj   +2 more sources