Results 41 to 50 of about 25,279 (271)

Early Freezing of Gait: Atypical versus Typical Parkinson Disorders

Parkinson's Disease, 2015
In 18 months, 850 patients were referred to Muhammad Ali Parkinson Center (MAPC). Among them, 810 patients had typical Parkinson disease (PD) and 212 had PD for ≤5 years. Among the 212 patients with early PD, 27 (12.7%) had freezing of gait (FOG).
Abraham Lieberman, Aman Deep, Rohit Dhall, An Tran, Ming-Jai Liu   +4 more
doaj   +1 more source

Clinical Variability of SYNJ1-Associated Early-Onset Parkinsonism

Frontiers in Neurology, 2021
Autosomal recessive early-onset parkinsonism is clinically and genetically heterogeneous. Mutations of three genes, PRKN, PINK1, and DJ-1 cause pure phenotypes usually characterized by levodopa-responsive Parkinson's disease.
Suzanne Lesage, Graziella Mangone, Christelle Tesson, Hélène Bertrand, Mustapha Benmahdjoub, Selma Kesraoui, Mohamed Arezki, Andrew Singleton, Jean-Christophe Corvol, Alexis Brice   +9 more
doaj   +1 more source

Corticobasal syndrome: neuroimaging and neurophysiological advances [PDF]

, 2019
Corticobasal degeneration (CBD) is a neurodegenerative condition characterized by 4R-tau protein deposition in several brain regions that clinically manifests itself as a heterogeneous atypical parkinsonism typically expressing in the adulthood.
Asci, Francesco, Berardelli, Alfredo, Bologna, Matteo, Colosimo, Carlo, Di Stasio, Flavio, Fabbrini, Giovanni, Marsili, Luca, Pantano, Patrizia, Suppa, Antonio, Upadhyay, Neeraj   +9 more
core   +1 more source

PLA2G6 Mutations Related to Distinct Phenotypes: A New Case with Early-onset Parkinsonism

Tremor and Other Hyperkinetic Movements, 2016
Background: PLA2G6-associated neurodegeneration (PLAN) is a recessive neurodegenerative disorder characterized by three distinct phenotypes: infantile neuroaxonal dystrophy (INAD), atypical neuroaxonal dystrophy (atypical NAD), and PLA2G6-related ...
Anamika Giri, Gamze Guven, Hasmet Hanagasi, Ann-Kathrin Hauser, Nihan Erginul-Unaltuna, Basar Bilgic, Hakan Gurvit, Peter Heutink, Thomas Gasser, Ebba Lohmann, Javier Simón-Sánchez   +10 more
doaj   +1 more source

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W, Duara, Ranjan, Graff-Radford, Neil R, Josephs, Keith A, Litvan, Irene, Murray, Melissa E, Sakae, Nobutaka, Uitti, Ryan J, Wszolek, Zbigniew K   +8 more
core   +1 more source

Sleep Disorders in Atypical Parkinsonism [PDF]

Movement Disorders Clinical Practice, 2014
AbstractSleep disorders are commonly observed in atypical parkinsonism, with particular disorders occurring more frequently in specific parkinsonian disorders. Multiple system atrophy (MSA) is a synucleinopathy often associated with nocturnal stridor, which is a serious, but treatable, condition highly specific to MSA.
Sabra M, Abbott, Aleksandar, Videnovic
openaire   +2 more sources

Effectiveness of an Inpatient Movement Disorders Program for Patients with Atypical Parkinsonism

Parkinson's Disease, 2012
This paper investigated the effectiveness of an inpatient movement disorders program for patients with atypical parkinsonism, who typically respond poorly to pharmacologic intervention and are challenging to rehabilitate as outpatients.
Anna D. Hohler, Jyeming M. Tsao, Douglas I. Katz, T. Joy DiPiero, Christina L. Hehl, Alissa Leonard, Valerie Allen, Maura Gardner, Heidi Phenix, Marie Saint-Hilaire, Terry Ellis   +10 more
doaj   +1 more source

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease [PDF]

, 2016
Funded by Parkinson's UK National Institute for Health Research (NIHR) DeNDRoN network NIHR Newcastle Biomedical Research Unit Newcastle University NIHR funded Biomedical Research Centre in CambridgePeer reviewedPublisher ...
Bajaj, Nin, Barker, Roger A, Ben-Shlomo, Yoav, Burn, David J, Grosset, Donald G, Grosset, Katherine A, Hardy, John, Lawton, Michael A, Malek, Naveed, Marrinan, Sarah L, Morris, Huw R, PRoBaND Clinical Consortium, Swallow, Diane M A, Williams, Nigel M, Wood, Nicholas   +14 more
core   +5 more sources

New insights into atypical parkinsonism [PDF]

Current Opinion in Neurology, 2011
Atypical parkinsonian disorders (APDs) comprise a heterogenous group of disorders including multiple system atrophy (MSA), dementia with Lewy bodies (DLB), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Based on literature published in 2010, we here review recent advances in the APD field.Genome-wide association studies have ...
Gregor K, Wenning, Florian, Krismer, Werner, Poewe   +2 more
openaire   +2 more sources

Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study. [PDF]

, 2017
ObjectiveParkinson's disease psychosis (PDP) is a frequent complication of idiopathic Parkinson's disease (iPD) with significant impact on quality of life and association with poorer outcomes.
Bizzarri, Cummings, Fernandez, Fernandez, Fénelon, Gama, Goldman, Hack, Hubbard, Kiferle, Lertxundi, McFarland, Meltzer, Meral, Mesquita, Mocci, Munhoz, Noel, Pagonabarraga, Prohorov, Rabey, Reichmann, Rolland, Seppi, Shotbolt, Starkstein, Thomas, Vanover, Weintraub, Zhu   +29 more
core   +2 more sources