Results 41 to 50 of about 590,699 (329)

Regional Selectivity of Neuromelanin Changes in the Substantia Nigra in Atypical Parkinsonism

Movement Disorders, 2022
Neurodegeneration in the substantia nigra pars compacta (SNc) in parkinsonian syndromes may affect the nigral territories differently.
Lydia Chougar, Emina Arsovic, Rahul Gaurav, Emma Biondetti, A. Faucher, R. Valabrègue, N. Pyatigorskaya, Gwendoline Dupont, F. Lejeune, Florence Cormier, Jean-Christophe Corvol, M. Vidailhet, B. Degos, D. Grabli, S. Lehéricy   +14 more
semanticscholar   +1 more source

Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism

Journal of Neurology Neurosurgery & Psychiatry, 2020
Objective Parkinson’s disease is characterised neuropathologically by α-synuclein aggregation. Currently, there is no blood test to predict the underlying pathology or distinguish Parkinson’s from atypical parkinsonian syndromes. We assessed the clinical
Cheng Jiang, F. Hopfner, Antigoni Katsikoudi, R. Hein, C. Catli, Samuel G. Evetts, Yongzhi Huang, Hong Wang, J. Ryder, G. Kuhlenbaeumer, G. Deuschl, A. Padovani, D. Berg, B. Borroni, M. Hu, Jason J. Davis, G. Tofaris   +16 more
semanticscholar   +1 more source

Atypical Antipsychotics and Parkinsonism [PDF]

Archives of Internal Medicine, 2005
Atypical antipsychotic agents are thought to be less likely than older typical agents to produce parkinsonism. This has not been well documented. We compared the risk of development of incident parkinsonism among older adults dispensed atypical relative to typical antipsychotics.Retrospective cohort study of all adults 66 years and older in Ontario. We
Rochon, Paula A., Stukel, Therese A., Sykora, Kathy, Gill, Sudeep S., Garfinkel, Susan, Anderson, Geoffrey M., Normand, Sharon-Lise T., Mamdani, Muhammad M., Lee, Philip E., Li, Ping, Bronskill, Susan E., Marras, Connie, Gurwitz, Jerry H.   +12 more
openaire   +3 more sources

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study

Frontiers in Aging Neuroscience, 2022
BackgroundParkinsonian syndromes may rarely occur in motor neuron disease (MND). However, previous studies are heterogeneous and mostly case reports or small case series.
Jacopo Pasquini, Jacopo Pasquini, Jacopo Pasquini, Francesca Trogu, Francesca Trogu, Claudia Morelli, Barbara Poletti, Floriano Girotti, Silvia Peverelli, Alberto Brusati, Alberto Brusati, Antonia Ratti, Antonia Ratti, Andrea Ciammola, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi   +17 more
doaj   +1 more source

Neuropsychiatric disturbances in atypical Parkinsonian disorders [PDF]

, 2018
Multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD) are the most common atypical parkinsonisms. These disorders are characterized by varying combinations of autonomic, cerebellar and pyramidal system ...
Belvisi, Daniele, Berardelli, Isabella, Fabbrini, Andrea, Fabbrini, Giovanni, Pasquini, Massimo, Pompili, Maurizio, Suppa, Antonio   +6 more
core   +1 more source

The Genetic Landscape of Parkinsonism-Related Dystonias and Atypical Parkinsonism-Related Syndromes

International Journal of Molecular Sciences, 2021
In recent decades, genetic research has nominated promising pathways and biological insights contributing to the etiological landscape of parkinsonism-related dystonias and atypical parkinsonism-related syndromes.
M. Diez-Fairen, Pilar Álvarez Jerez, Joos Berghausen, S. Bandres-Ciga   +3 more
semanticscholar   +1 more source

Corticobasal syndrome in a man with Gaucher disease type 1: Expansion of the understanding of the neurological spectrum

Molecular Genetics and Metabolism Reports, 2018
Gaucher disease (GD) is an autosomal recessive condition that results from a deficiency of the enzyme β-glucocerebrosidase. The increased risk of primary parkinsonism symptoms among individuals affected with GD and carriers for the disorder is well ...
Kunal C. Potnis, Lauren B. Flueckinger, Stephanie M. DeArmey, Roy N. Alcalay, Jeffrey W. Cooney, Priya S. Kishnani   +5 more
doaj   +1 more source

Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]

, 2017
Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger, Alcalay, Roy N., Babcock, Debra, Bowman, F. DuBois, Chen-Plotkin, Alice, David, Karen K., Dawson, Ted M., Dewey, Richard B., Jr., Foroud, Tatiana, German, Dwight, Gwinn, Katrina, Huang, Xuemei, Lungu, Codrin, Petyuk, Vlad, Potashkin, Judith A., Rosenthal, Liana S., Saunders-Pullman, Rachel, Scherzer, Clemens R., Sieber, Beth-Anne, St Hillaire-Clarke, Coryse, Sutherland, Margaret, Swanson-Fischer, Christine, Vaillancourt, David E., Walt, David R., West, Andrew B., Zhang, Jing   +25 more
core   +1 more source

First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes

npj Parkinson's Disease, 2021
To define the incidence, predictors and prognosis of the first hospital delirium episode in Parkinson’s disease (PD) and atypical parkinsonism (AP), we identified the first hospital episode of delirium after diagnosis in the Parkinsonism Incidence in ...
Samantha Green, Sarah L. Perrott, Andrew McCleary, Isobel Sleeman, Jodi Maple-Grødem, Carl E. Counsell, Angus D. Macleod   +6 more
doaj   +1 more source

Low dose of Rotigotine in post-stroke patients with vascular parkinsonism and obstructive sleep apnoea syndrome, effects on quality of life and rehabilitation therapy [PDF]

, 2017
Stroke is a frequent cause of disability in U.S.A. (200.000/ year). Aim: The aim of this study is to underline the effect of low dose of Rotigotine patches 2 mg/24 h, a complete dopamine agonist with continuous dopaminergic stimulation through the ...
Ceratti U, Dalmaso S, Fabrizio A, Maietta A, Marchitto N, Monaco P, Raimondi G, Sindona F   +7 more
core   +1 more source