Results 1 to 10 of about 228,504 (373)

New-onset IgG autoantibodies in hospitalized patients with COVID-19

Nature Communications, 2021
Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), is associated with a wide range of clinical manifestations, including autoimmune features and autoantibody production.
Guido Reifenberger, Abigail E Powell, Alex J Kuo   +2 more
exaly   +3 more sources

Myositis‐specific autoantibodies: an important tool to support diagnosis of myositis

Journal of Internal Medicine, 2016
The idiopathic inflammatory myopathies are characterized by muscle weakness, skin disease and internal organ involvement. Autoimmunity is known to have a role in myositis pathogenesis, and myositis‐specific autoantibodies, targeting important ...
Z. Betteridge, N. Mchugh
exaly   +2 more sources

Autoantibodies Targeting Intracellular and Extracellular Proteins in Autoimmunity

Frontiers in Immunology, 2021
Detecting autoantibodies provides foundational information for the diagnosis of most autoimmune diseases. An important pathophysiological distinction is whether autoantibodies are directed against extracellular or intracellular proteins.
Peter D Burbelo, Michael J Iadarola
exaly   +3 more sources

Autoantibodies in neurological disease

Nature Reviews Immunology, 2021
Harald Prüss
exaly   +2 more sources

VEGF controls microglial phagocytic response to amyloid-β

Frontiers in Cellular Neuroscience, 2023
Microglial cells are well known to be implicated in the pathogenesis of Alzheimer’s disease (AD), due to the impaired clearance of amyloid-β (Aβ) protein.
Priscille de Gea, Sarah Benkeder, Pauline Bouvet, Mélanie Aimard, Naura Chounlamountri, Jérôme Honnorat, Jérôme Honnorat, Le Duy Do, Le Duy Do, Claire Meissirel   +9 more
doaj   +1 more source

Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies

Frontiers in Immunology, 2022
Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial.
Christian P. Moritz, Christian P. Moritz, Christian P. Moritz, Le-Duy Do, Le-Duy Do, Yannick Tholance, Yannick Tholance, Yannick Tholance, Pierre-Baptiste Vallayer, Véronique Rogemond, Véronique Rogemond, Bastien Joubert, Bastien Joubert, Karine Ferraud, Karine Ferraud, Coralie La Marca, Coralie La Marca, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jean-Philippe Camdessanché, Jérôme Honnorat, Jérôme Honnorat, Jérôme Honnorat, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine, Jean-Christophe Antoine   +29 more
doaj   +1 more source

Autoantibodies against complement factor B in rheumatoid arthritis

Frontiers in Immunology, 2023
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder affecting the joints. Many patients carry anti-citrullinated protein autoantibodies (ACPA).
Alexandra T. Matola, Alexandra T. Matola, Angéla Fülöp, Bernadette Rojkovich, György Nagy, György Nagy, György Nagy, György Nagy, Gabriella Sármay, Mihály Józsi, Mihály Józsi, Barbara Uzonyi, Barbara Uzonyi   +12 more
doaj   +1 more source

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon
J. Manry, P. Bastard, A. Gervais, Tom Le Voyer, J. Rosain, Q. Philippot, E. Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, M. García-Prat, L. Bizien, Alba Parra-Martínez, Rui Yang, L. Haljasmägi, M. Migaud, Karita Särekannu, Julia Maslovskaja, N. de Prost, Y. Tandjaoui-Lambiotte, C. Luyt, Blanca Amador-Borrero, A. Gaudet, J. Poissy, P. Morel, P. Richard, F. Cognasse, J. Troya, S. Trouillet-Assant, A. Belot, K. Saker, P. Garçon, Jacques G. Rivière, J. Lagier, S. Gentile, Lindsey B. Rosen, E. Shaw, T. Morio, J. Tanaka, D. Dalmau, P. Tharaux, D. Sène, A. Stépanian, B. Mégarbane, Vasiliki Triantafyllia, A. Fekkar, J. Heath, J. Franco, J. Anaya, J. Solé-Violán, L. Imberti, A. Biondi, P. Bonfanti, R. Castagnoli, O. Delmonte, Yu Zhang, A. Snow, S. Holland, C. Biggs, M. Moncada-Vélez, A. Arias, Lazaro Lorenzo, S. Boucherit, D. Anglicheau, A. Planas, F. Haerynck, S. Duvlis, T. Ozcelik, S. Keleş, A. Bousfiha, Jalila El Bakkouri, C. Ramírez-Santana, S. Paul, Q. Pan-Hammarström, L. Hammarström, A. Dupont, A. Kurolap, C. Metz, A. Aiuti, G. Casari, V. Lampasona, F. Ciceri, L. Barreiros, E. Domínguez-Garrido, M. Vidigal, M. Zatz, D. van de Beek, S. Sahanic, I. Tancevski, Y. Stepanovskyy, O. Boyarchuk, Y. Nukui, M. Tsumura, L. Vidaur, S. Tangye, S. Burrel, D. Duffy, L. Quintana-Murci, A. Klocperk, Nelli Y. Kann, A. Shcherbina, Y. Lau, D. Leung, Matthieu Coulongeat, J. Marlet, R. Koning, L. Reyes, Angélique Chauvineau-Grenier, F. Venet, G. Monneret, M. Nussenzweig, R. Arrestier, Idris Boudhabhay, Hagit Baris-Feldman, D. Hagin, J. Wauters, I. Meyts, A. Dyer, S. Kennelly, Nollaig M. Bourke, R. Halwani, F. Sharif-Askari, K. Dorgham, J. Sallette, Souad Mehlal Sedkaoui, Suzan A. AlKhater, R. Rigo-Bonnin, F. Morandeira, Lucie Roussel, D. Vinh, C. Erikstrup, A. Condino-Neto, Carolina Prando, Anastasiia Bondarenko, A. Spaan, L. Gilardin, J. Fellay, S. Lyonnet, K. Bilguvar, R. Lifton, Shrikant Mane, Mark S. Anderson, B. Boisson, V. Béziat, Shen-Ying Zhang, E. Andreakos, O. Hermine, A. Pujol, P. Peterson, T. Mogensen, L. Rowen, J. Mond, S. Debette, X. D. de Lamballerie, C. Burdet, L. Bouadma, M. Zins, P. Soler-Palacín, R. Colobran, G. Gorochov, X. Solanich, S. Susen, J. Martinez-Picado, D. Raoult, M. Vasse, P. Gregersen, L. Piemonti, C. Rodríguez-Gallego, L. Notarangelo, H. Su, K. Kisand, S. Okada, A. Puel, E. Jouanguy, C. Rice, P. Tiberghien, Qian Zhang, J. Casanova, L. Abel, A. Cobat   +178 more
semanticscholar   +1 more source

The significance of preclinical anti-BP180 autoantibodies

Frontiers in Immunology, 2022
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai, Kentaro Izumi, Shoko Mai, Hideyuki Ujiie   +3 more
doaj   +1 more source

Autoantibodies predict type 1 diabetes after gestational diabetes – a 23-year cohort study

Frontiers in Endocrinology, 2023
ObjectiveTo study the predictive value of autoantibodies for type 1 (T1DM) and type 2 (T2DM) diabetes morbidity after gestational diabetes (GDM) in a 23-year follow-up study.DesignProspective population-based cohort study.MethodsWe studied 391 women with
Kaisu Luiro, Anna-Maaria Auvinen, Anna-Maaria Auvinen, Juha Auvinen, Juha Auvinen, Jari Jokelainen, Ilkka Järvelä, Mikael Knip, Mikael Knip, Mikael Knip, Juha S. Tapanainen, Juha S. Tapanainen, Juha S. Tapanainen, Juha S. Tapanainen   +13 more
doaj   +1 more source