Results 1 to 10 of about 227,787 (289)

Autoantibodies Targeting Intracellular and Extracellular Proteins in Autoimmunity

Frontiers in Immunology, 2021
Detecting autoantibodies provides foundational information for the diagnosis of most autoimmune diseases. An important pathophysiological distinction is whether autoantibodies are directed against extracellular or intracellular proteins.
Peter D. Burbelo, Michael J. Iadarola, Jason M. Keller, Blake M. Warner   +3 more
doaj   +2 more sources

Anticytokine Autoantibodies: Association with Infection and Immune Dysregulation

Antibodies, 2016
The association of autoantibodies to cytokines with immune deficiency, autoimmunity and/or immune dysregulation is increasingly being recognized. For example, autoantibodies to interferon gamma have been found to be associated with chronic, treatment ...
Vijaya Knight, Patricia A. Merkel, Michael D. O’Sullivan   +2 more
doaj   +1 more source

Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non‐ischaemic heart failure

ESC Heart Failure, 2023
Aims A causal link between non‐ischaemic heart failure (HF) and humoral autoimmunity against G‐protein‐coupled receptors (GPCR) remains unclear except for Chagas' cardiomyopathy.
Elric Zweck, Maximilian Karschnia, Daniel Scheiber, Harald Heidecke, Ralf Dechend, Carmen Barthuber, Sina Kaufmann, Malte Kelm, Michael Roden, Ralf Westenfeld, Julia Szendrödi, Fritz Boege   +11 more
doaj   +1 more source

Detection of Novel Autoantibodies to Nucleolin's RNA-binding Domains as a Serum Tumor Biomarker Through ELISA

Iranian Journal of Allergy, Asthma and Immunology, 2022
Expression and location of nucleolin are often abnormal in malignancies, which may result in the production of autoantibodies. Despite this, the identification of such autoantibodies may be essential for the early diagnosis and prognosis of cancers.
Fatemeh Ezzatifar, Alireza Rafiei, Reza Valadan, Hossein Asgarian-Omran, Mahmood Jeddi-Tehrani   +4 more
doaj   +1 more source

ACPAs Are Much More Than Diagnostic Autoantibodies

Rambam Maimonides Medical Journal, 2016
Anti-citrullinated protein autoantibodies (ACPAs) are the major autoantibodies in rheumatoid arthritis (RA). Anti-citrullinated protein autoantibodies are directed against different citrullinated antigens, including filaggrin, fibrinogen, vimentin, and ...
Abdulla Watad, Howard Amital
doaj   +1 more source

Cytokine autoantibodies in SARS-CoV-2 prepandemic and intrapandemic samples from an SLE cohort

Lupus Science and Medicine, 2022
Cytokine autoantibodies, particularly those directed to type I interferon (T1IFN), have been reported to portend an increased risk of severe COVID-19.
Ann Elaine Clarke, Marvin J Fritzler, Michelle Jung, May Y Choi, Francesca S Cardwell, Katherine Buhler, Hannah Mathew, Meifeng Zhang, Heather Waldhauser   +8 more
doaj   +1 more source

The antibody repertoire of autoimmune sensory neuronopathies targets pathways of the innate and adaptive immune system. An autoantigenomic approach

Journal of Translational Autoimmunity
Sensory neuronopathies (SNN) encompass diverse etiologies, with autoimmunity playing a major role through both cellular and humoral responses. To investigate the humoral autoantibody repertoire in autoimmune SNN, we conducted a retrospective cohort study
Christian P. Moritz, Yannick Tholance, Nadia Boutahar, Coralie Borowczyk, Anne-Emmanuelle Berger, Stéphane Paul, Jean-Christophe Antoine, Jean-Philippe Camdessanché   +7 more
doaj   +1 more source

COULD BE CONSIDERED SERUM ANTI-S-100 AUTOANTIBODIES A BIOMARKER IN PATIENTS WITH ACUTE NON-CARDIOEMBOLIC ISCHEMIC STROKE? [PDF]

Romanian Medical Journal, 2018
In ischemic stroke patients there were found autoantibodies against brain epitopes. The presence of anti-S-100 autoantibodies may reflect alteration and dysfunction of the blood-brain barrier.
Inimioara Mihaela Cojocaru, Manole Cojocaru, Violeta Sapira, Daniela Stefănescu   +3 more
doaj   +1 more source

Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant

Frontiers in Immunology, 2021
Lung transplant patients have the lowest long-term survival rates compared to other solid organ transplants. The complications after lung transplantation such as primary graft dysfunction (PGD) and ultimately chronic lung allograft dysfunction (CLAD) are
Alexander McQuiston, Alexander McQuiston, Amir Emtiazjoo, Peggi Angel, Tiago Machuca, Jason Christie, Carl Atkinson   +6 more
doaj   +1 more source

Psychopathology of psychiatric patients presenting autoantibodies against neuroglial antigens

Frontiers in Psychiatry, 2022
BackgroundAutoantibody-mediated psychiatric disorder is often difficult to diagnose as the clinical features of psychiatric disorder associated with neural autoantibodies are often similar.
Insa Maria Grenzer, Insa Maria Grenzer, Aaron Levin Juhl, Aaron Levin Juhl, Bianca Teegen, Dirk Fitzner, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Niels Hansen, Niels Hansen   +10 more
doaj   +1 more source