Results 1 to 10 of about 242,290 (361)
A novel platform for isotype-specific testing of autoantibodies. [PDF]
PLoS ONE, 2019 The objective of this study was to test if a novel platform could be used for isotype-specific autoantibody testing in humans. Further, we evaluated if testing with this novel platform enables earlier detection of insulin autoantibodies in individuals ...
Kaylene L Carter +4 more
doaj +3 more sources
Autoantibodies Targeting Intracellular and Extracellular Proteins in Autoimmunity
Frontiers in Immunology, 2021 Detecting autoantibodies provides foundational information for the diagnosis of most autoimmune diseases. An important pathophysiological distinction is whether autoantibodies are directed against extracellular or intracellular proteins.
Peter D Burbelo, Michael J Iadarola
exaly +3 more sources
VEGF controls microglial phagocytic response to amyloid-β
Frontiers in Cellular Neuroscience, 2023 Microglial cells are well known to be implicated in the pathogenesis of Alzheimer’s disease (AD), due to the impaired clearance of amyloid-β (Aβ) protein.
Priscille de Gea +9 more
doaj +1 more source
Frontiers in Immunology, 2022 Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial.
Christian P. Moritz +29 more
doaj +1 more source
Autoantibodies against complement factor B in rheumatoid arthritis
Frontiers in Immunology, 2023 Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder affecting the joints. Many patients carry anti-citrullinated protein autoantibodies (ACPA).
Alexandra T. Matola +12 more
doaj +1 more source
Flow cytofluorimetric analysis of anti-LRP4 (LDL receptor-related protein 4) autoantibodies in Italian patients with Myasthenia gravis [PDF]
, 2015 Background: Myasthenia gravis (MG) is an autoimmune disease in which 90% of patients have autoanti-bodies against the muscle nicotinic acetylcholine receptor (AChR), while autoantibodies to muscle-specific tyrosine kinase (MuSK) have been detected in ...
Antonini, Giovanni +11 more
core +10 more sources
The significance of preclinical anti-BP180 autoantibodies
Frontiers in Immunology, 2022 Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease. Although the pathomechanism of BP onset has yet to be elucidated in detail, BP autoantibodies targeting two hemidesmosomal components, BP180 and BP230, are known to ...
Yosuke Mai +3 more
doaj +1 more source
Autoantibodies predict type 1 diabetes after gestational diabetes – a 23-year cohort study
Frontiers in Endocrinology, 2023 ObjectiveTo study the predictive value of autoantibodies for type 1 (T1DM) and type 2 (T2DM) diabetes morbidity after gestational diabetes (GDM) in a 23-year follow-up study.DesignProspective population-based cohort study.MethodsWe studied 391 women with
Kaisu Luiro +13 more
doaj +1 more source
Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease
npj Parkinson's Disease, 2022 The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes.
Carmen M. Labandeira +8 more
doaj +1 more source
Case Reports in Nephrology and Dialysis, 2021 Membranous nephropathy (MN) is currently classified as either primary – often associated with positive anti-phospholipase-A2 receptor (PLA2R) autoantibodies – or as secondary – associated with malignancy, infection, medications, or autoimmune disease. We
Lyle W. Baker +3 more
doaj +1 more source