Results 21 to 30 of about 139,183 (310)

Detection of Novel Autoantibodies to Nucleolin's RNA-binding Domains as a Serum Tumor Biomarker Through ELISA

Iranian Journal of Allergy, Asthma and Immunology, 2022
Expression and location of nucleolin are often abnormal in malignancies, which may result in the production of autoantibodies. Despite this, the identification of such autoantibodies may be essential for the early diagnosis and prognosis of cancers.
Fatemeh Ezzatifar, Alireza Rafiei, Reza Valadan, Hossein Asgarian-Omran, Mahmood Jeddi-Tehrani   +4 more
doaj   +1 more source

Anticytokine Autoantibodies: Association with Infection and Immune Dysregulation

Antibodies, 2016
The association of autoantibodies to cytokines with immune deficiency, autoimmunity and/or immune dysregulation is increasingly being recognized. For example, autoantibodies to interferon gamma have been found to be associated with chronic, treatment ...
Vijaya Knight, Patricia A. Merkel, Michael D. O’Sullivan   +2 more
doaj   +1 more source

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

Autoimmunity, 2021
Objectives Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been discovered and have become available in diagnostic assays.
Wynand Alkema, Hans Koenen, Brigit E. Kersten, Charlotte Kaffa, Jacqueline W. B. Dinnissen, Jan G. M. C. Damoiseaux, Irma Joosten, Sophie Driessen-Diks, Renate G. van der Molen, Madelon C. Vonk, Ruben L. Smeets   +10 more
doaj   +1 more source

Stratification of Systemic Lupus Erythematosus Patients Using Gene Expression Data to Reveal Expression of Distinct Immune Pathways [PDF]

, 2020
Systemic lupus erythematosus (SLE) is the tenth leading cause of death in females 15-24 years old in the US. The diversity of symptoms and immune pathways expressed in SLE patients causes difficulties in treating SLE as well as in new clinical trials.
arxiv   +1 more source

Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non‐ischaemic heart failure

ESC Heart Failure, 2023
Aims A causal link between non‐ischaemic heart failure (HF) and humoral autoimmunity against G‐protein‐coupled receptors (GPCR) remains unclear except for Chagas' cardiomyopathy.
Elric Zweck, Maximilian Karschnia, Daniel Scheiber, Harald Heidecke, Ralf Dechend, Carmen Barthuber, Sina Kaufmann, Malte Kelm, Michael Roden, Ralf Westenfeld, Julia Szendrödi, Fritz Boege   +11 more
doaj   +1 more source

Multiple rather than specific autoantibodies were identified in irritable bowel syndrome with HuProt™ proteome microarray

Frontiers in Physiology, 2022
Immune activation and several autoantibodies might be involved in the pathophysiology of irritable bowel syndrome (IBS). We aimed to identify serum biomarkers for IBS by HuProt™ microarray. IBS patients met Rome III criteria were enrolled. Control groups
Wenjuan Fan, Wenjuan Fan, Xiucai Fang, Chaojun Hu, Guijun Fei, Qiyun Xiao, Yongzhe Li, Yongzhe Li, Xiaoqing Li, Jackie D. Wood, Xuan Zhang   +10 more
doaj   +1 more source

Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

Arthritis Research & Therapy, 2018
Background The close temporal association between onset of some connective tissue diseases and cancer suggests a paraneoplastic association.
Zoe E. Betteridge, Lynsey Priest, Robert G. Cooper, Neil J. McHugh, Fiona Blackhall, Janine A. Lamb   +5 more
doaj   +1 more source

Immunoglobulin E and G autoantibodies against eosinophil proteins in children and adults with asthma and healthy subjects

World Allergy Organization Journal, 2023
Background: Autoimmune IgG response has been described in the pathogenesis of asthma in adults, but IgE autoimmunity has been little explored. Considering high levels of blood eosinophils and immunoglobulin E in asthmatic patients, the possibility of IgE
Jorge Sánchez, MD, MSc, EAC, PhD, Andres Sánchez Biol, MSc, Marlon Múnera Biol, PhD, Elizabeth García, MD, EAC, Juan-Felipe López, MD, MSc   +4 more
doaj  

Type 1 diabetes-related autoimmune antibodies in women with gestational diabetes mellitus and the long-term risk for glucose intolerance

Frontiers in Endocrinology, 2022
AimsTo characterize women with gestational diabetes mellitus (GDM) positive for type 1 diabetes-related autoimmune antibodies (T1D-related autoantibodies) in pregnancy and to evaluate their risk for long-term glucose intolerance.MethodsIn a multi-centric
Kaat Beunen, Lies Vercauter, Paul Van Crombrugge, Carolien Moyson, Johan Verhaeghe, Sofie Vandeginste, Hilde Verlaenen, Chris Vercammen, Toon Maes, Els Dufraimont, Nele Roggen, Christophe De Block, Yves Jacquemyn, Farah Mekahli, Katrien De Clippel, Annick Van Den Bruel, Anne Loccufier, Annouschka Laenen, Roland Devlieger, Chantal Mathieu, Katrien Benhalima   +20 more
doaj   +1 more source

ACPAs Are Much More Than Diagnostic Autoantibodies

Rambam Maimonides Medical Journal, 2016
Anti-citrullinated protein autoantibodies (ACPAs) are the major autoantibodies in rheumatoid arthritis (RA). Anti-citrullinated protein autoantibodies are directed against different citrullinated antigens, including filaggrin, fibrinogen, vimentin, and ...
Abdulla Watad, Howard Amital
doaj   +1 more source