Results 21 to 30 of about 151,970 (246)

ACPAs Are Much More Than Diagnostic Autoantibodies

Rambam Maimonides Medical Journal, 2016
Anti-citrullinated protein autoantibodies (ACPAs) are the major autoantibodies in rheumatoid arthritis (RA). Anti-citrullinated protein autoantibodies are directed against different citrullinated antigens, including filaggrin, fibrinogen, vimentin, and ...
Abdulla Watad, Howard Amital
doaj   +1 more source

Cytokine autoantibodies in SARS-CoV-2 prepandemic and intrapandemic samples from an SLE cohort

Lupus Science and Medicine, 2022
Cytokine autoantibodies, particularly those directed to type I interferon (T1IFN), have been reported to portend an increased risk of severe COVID-19.
Ann Elaine Clarke, Marvin J Fritzler, Michelle Jung, May Y Choi, Francesca S Cardwell, Katherine Buhler, Hannah Mathew, Meifeng Zhang, Heather Waldhauser   +8 more
doaj   +1 more source

COULD BE CONSIDERED SERUM ANTI-S-100 AUTOANTIBODIES A BIOMARKER IN PATIENTS WITH ACUTE NON-CARDIOEMBOLIC ISCHEMIC STROKE? [PDF]

Romanian Medical Journal, 2018
In ischemic stroke patients there were found autoantibodies against brain epitopes. The presence of anti-S-100 autoantibodies may reflect alteration and dysfunction of the blood-brain barrier.
Inimioara Mihaela Cojocaru, Manole Cojocaru, Violeta Sapira, Daniela Stefănescu   +3 more
doaj   +1 more source

Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant

Frontiers in Immunology, 2021
Lung transplant patients have the lowest long-term survival rates compared to other solid organ transplants. The complications after lung transplantation such as primary graft dysfunction (PGD) and ultimately chronic lung allograft dysfunction (CLAD) are
Alexander McQuiston, Alexander McQuiston, Amir Emtiazjoo, Peggi Angel, Tiago Machuca, Jason Christie, Carl Atkinson   +6 more
doaj   +1 more source

The antibody repertoire of autoimmune sensory neuronopathies targets pathways of the innate and adaptive immune system. An autoantigenomic approach

Journal of Translational Autoimmunity
Sensory neuronopathies (SNN) encompass diverse etiologies, with autoimmunity playing a major role through both cellular and humoral responses. To investigate the humoral autoantibody repertoire in autoimmune SNN, we conducted a retrospective cohort study
Christian P. Moritz, Yannick Tholance, Nadia Boutahar, Coralie Borowczyk, Anne-Emmanuelle Berger, Stéphane Paul, Jean-Christophe Antoine, Jean-Philippe Camdessanché   +7 more
doaj   +1 more source

Psychopathology of psychiatric patients presenting autoantibodies against neuroglial antigens

Frontiers in Psychiatry, 2022
BackgroundAutoantibody-mediated psychiatric disorder is often difficult to diagnose as the clinical features of psychiatric disorder associated with neural autoantibodies are often similar.
Insa Maria Grenzer, Insa Maria Grenzer, Aaron Levin Juhl, Aaron Levin Juhl, Bianca Teegen, Dirk Fitzner, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Niels Hansen, Niels Hansen   +10 more
doaj   +1 more source

Investigation of myositis and scleroderma specific autoantibodies in patients with lung cancer

Arthritis Research & Therapy, 2018
Background The close temporal association between onset of some connective tissue diseases and cancer suggests a paraneoplastic association.
Zoe E. Betteridge, Lynsey Priest, Robert G. Cooper, Neil J. McHugh, Fiona Blackhall, Janine A. Lamb   +5 more
doaj   +1 more source

Autoantibodies Targeting Intracellular and Extracellular Proteins in Autoimmunity

Frontiers in Immunology, 2021
Detecting autoantibodies provides foundational information for the diagnosis of most autoimmune diseases. An important pathophysiological distinction is whether autoantibodies are directed against extracellular or intracellular proteins.
Peter D. Burbelo, Michael J. Iadarola, Jason M. Keller, Blake M. Warner   +3 more
doaj   +1 more source

Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Biomedicines
Background: Membranoproliferative glomerulonephritis (MPGN) is an umbrella term for chronic disorders affecting the glomeruli. MPGN is often accompanied by the presence of autoantibodies against complement components.
Alexandra T. Matola, Dorottya Csuka, Ágnes Szilágyi, Michael Rudnicki, Zoltán Prohászka, Mihály Józsi, Barbara Uzonyi   +6 more
doaj   +1 more source

Multiple rather than specific autoantibodies were identified in irritable bowel syndrome with HuProt™ proteome microarray

Frontiers in Physiology, 2022
Immune activation and several autoantibodies might be involved in the pathophysiology of irritable bowel syndrome (IBS). We aimed to identify serum biomarkers for IBS by HuProt™ microarray. IBS patients met Rome III criteria were enrolled. Control groups
Wenjuan Fan, Wenjuan Fan, Xiucai Fang, Chaojun Hu, Guijun Fei, Qiyun Xiao, Yongzhe Li, Yongzhe Li, Xiaoqing Li, Jackie D. Wood, Xuan Zhang   +10 more
doaj   +1 more source