Aims A causal link between non‐ischaemic heart failure (HF) and humoral autoimmunity against G‐protein‐coupled receptors (GPCR) remains unclear except for Chagas' cardiomyopathy.
Elric Zweck +11 more
doaj +1 more source
Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application [PDF]
Background The insulinoma associated protein tyrosine phosphatase 2 (IA-2) is one of the immunodominant autoantigens involved in the autoimmune attack to the beta-cell in Type 1 Diabetes Mellitus.
A Trabucchi +95 more
core +5 more sources
BackgroundAnti-neural autoantibodies associated with psychiatric syndromes is an increasing phenomenon in psychiatry. Our investigation aimed to assess the frequency and type of neural autoantibodies associated with distinct psychiatric syndromes in a ...
Niels Hansen +10 more
doaj +1 more source
Screening for type 1 diabetes-, thyroid-, gastric-, and adrenal-specific humoral autoimmunity in 529 children and adolescents with celiac disease at diagnosis identifies as positive one in every nine patients [PDF]
No abstract ...
Anania, Caterina +9 more
core +1 more source
ACPAs Are Much More Than Diagnostic Autoantibodies
Anti-citrullinated protein autoantibodies (ACPAs) are the major autoantibodies in rheumatoid arthritis (RA). Anti-citrullinated protein autoantibodies are directed against different citrullinated antigens, including filaggrin, fibrinogen, vimentin, and ...
Abdulla Watad, Howard Amital
doaj +1 more source
Cytokine autoantibodies in SARS-CoV-2 prepandemic and intrapandemic samples from an SLE cohort
Cytokine autoantibodies, particularly those directed to type I interferon (T1IFN), have been reported to portend an increased risk of severe COVID-19.
Ann Elaine Clarke +8 more
doaj +1 more source
Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Brumberger, V. +7 more
core +1 more source
Set Up for Failure: Pre-Existing Autoantibodies in Lung Transplant
Lung transplant patients have the lowest long-term survival rates compared to other solid organ transplants. The complications after lung transplantation such as primary graft dysfunction (PGD) and ultimately chronic lung allograft dysfunction (CLAD) are
Alexander McQuiston +6 more
doaj +1 more source
Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham +105 more
core +2 more sources
COULD BE CONSIDERED SERUM ANTI-S-100 AUTOANTIBODIES A BIOMARKER IN PATIENTS WITH ACUTE NON-CARDIOEMBOLIC ISCHEMIC STROKE? [PDF]
In ischemic stroke patients there were found autoantibodies against brain epitopes. The presence of anti-S-100 autoantibodies may reflect alteration and dysfunction of the blood-brain barrier.
Inimioara Mihaela Cojocaru +3 more
doaj +1 more source

