Results 121 to 130 of about 59,330 (297)
The purpose of the current study was to analyze the binding patterns of serum autoantibodies from juvenile idiopathic arthritis (JIA) and JIA-associated uveitis (JIAU) patients to proteomes from different ocular tissues and to identify potential ocular ...
Martin Busch+13 more
doaj +1 more source
On the Lipophilic Nature of Autoreactive IgE in Chronic Spontaneous Urticaria [PDF]
Chronic spontaneous urticaria (CSU) is a skin disease related to autoreactive IgE in at least a subgroup of patients. However, the nature of this autoreactive IgE remains poorly characterized.
Church, Martin K.+3 more
core +1 more source
Molecular characteristics of the Goodpasture autoantigen
Goodpasture syndrome is an autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary hemorrhage. The clinical manifestations are caused by autoantibodies that bind to a constituent, termed the Goodpasture autoantigen, of alveolar and glomerular basement membranes.
Sripad Gunwar+9 more
openaire +2 more sources
NETosis: A bridge between cancer and autoimmunity
Rheumatology &Autoimmunity, EarlyView.
Niloufar Orooji, Manouchehr Fadaee
wiley +1 more source
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio+1 more
wiley +1 more source
Immune Modulation as a Treatment for Abdominal Aortic Aneurysms [PDF]
In the United States, over 200,000 new patients are diagnosed with abdominal aortic aneurysm (AAA) each year. Consequently, over 40,000 highly morbid aortic reconstructions are performed each year to prevent aneurysm rupture, a catastrophic event ...
Murphy, Michael P., Wang, S. Keisin
core +1 more source
A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li+4 more
wiley +1 more source
Abstract Aims The objective of this study was to compare the risk of developing type 1 diabetes in individuals with celiac disease, hyperthyroidism and hypothyroidism to that of individuals without those conditions. Materials and Methods In this retrospective, observational, matched‐cohort study based on real‐world claims data, individuals with at ...
Steve V. Edelman+5 more
wiley +1 more source
Increased Polyamines Alter Chromatin and Stabilize Autoantigens in Autoimmune Diseases
Polyamines are small cations with unique combinations of charge and length that give them many putative interactions in cells. Polyamines are essential since they are involved in replication, transcription, translation, and stabilization of macro ...
W. Brooks
semanticscholar +1 more source
Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians
Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais+1 more
wiley +1 more source