Results 121 to 130 of about 64,232 (366)

Microbial Transglutaminase Increases Uptake and Translocation of Gliadin Peptides in the Human Intestinal Epithelium

Molecular Nutrition &Food Research, EarlyView.
The bacterial enzyme microbial transglutaminase (mTG) is widely used in the food industry as a technological aid to improve textural properties of a multitude of food products. mTG mimics the enzymatic function of human transglutaminase 2 (TG2) and may play a role in the pathogenesis of celiac disease.
Sebastian Stricker, Jan De Laffolie, Klaus‐Peter Zimmer, Silvia Rudloff   +3 more
wiley   +1 more source

Identification of Ocular Autoantigens Associated With Juvenile Idiopathic Arthritis-Associated Uveitis

Frontiers in Immunology, 2019
The purpose of the current study was to analyze the binding patterns of serum autoantibodies from juvenile idiopathic arthritis (JIA) and JIA-associated uveitis (JIAU) patients to proteomes from different ocular tissues and to identify potential ocular ...
Martin Busch, Kira Leona Wefelmeyer, Karoline Walscheid, Kai Rothaus, Dirk Bauer, Cornelia A. Deeg, Roxane L. Degroote, Doreen Ackermann, Simone König, Solon Thanos, Maren Kasper, Arnd Heiligenhaus, Arnd Heiligenhaus, Arnd Heiligenhaus   +13 more
doaj   +1 more source

Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies

Journal of Experimental Medicine, 2013
Immunological tolerance to self-antigen impairs humoral responses to HIV-1.
Guang Yang, T. Holl, Yang Liu, Yi Li, Xiaozhi Lu, N. Nicely, T. Kepler, S. Munir Alam, H. Liao, D. Cain, L. Spicer, J. L. VandeBerg, B. Haynes, G. Kelsoe   +13 more
semanticscholar   +1 more source

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

ChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid, Nourelhouda Mekhadmi, Randa Mlik, Assia Bentahar, Kamilia Bireche, Bariza Frih, Walid Boussebaa, Aicha Mouane, Nezar Cherrada, Ana Sanches Silva, Messaouda Dekmouche, Lazhar Bechki, Khalid Mashay Al‐Anazi, Mohammad Abul Farah, Ahmad Ali   +14 more
wiley   +1 more source

Rat models of autoimmune uveitis [PDF]

, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria, Thurau, Stephan R., Wildner, Gerhild   +2 more
core   +1 more source

Artificial Intelligence and the Evolving Landscape of Immunopeptidomics

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Background Immunopeptidomics is the large‐scale study of peptides presented by major histocompatibility complex (MHC) molecules and plays a central role in neoantigen discovery and cancer immunotherapy. However, the complexity of mass spectrometry data, the diversity of peptide sources, and variability in immune responses present major ...
Thanh Hoa Vo, Edel McNeela, Orla O'Donovan, Sweta Rani, Jai Prakash Mehta   +4 more
wiley   +1 more source

Ultrastructural localization of guinea pig spermatozoal autoantigens on germinal cells by immunoperoxidase techniques. [PDF]

, 1979
Philippe P. Le Bouteiller, F Toullet, S. Righenzi, G A Voisin   +3 more
openalex   +1 more source

Molecular characteristics of the Goodpasture autoantigen

Kidney International, 1993
Goodpasture syndrome is an autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary hemorrhage. The clinical manifestations are caused by autoantibodies that bind to a constituent, termed the Goodpasture autoantigen, of alveolar and glomerular basement membranes.
Sripad Gunwar, Sripad Gunwar, Milton E. Noelken, Milton E. Noelken, Billy G. Hudson, Raghuram Kalluri, Mariko Mariyama, Mariko Mariyama, Stephen T. Reeders, Stephen T. Reeders   +9 more
openaire   +2 more sources

Antigen-specific T cell responses in autoimmune diabetes

Frontiers in Immunology
Autoimmune diabetes is a disease characterized by the selective destruction of insulin-secreting β-cells of the endocrine pancreas by islet-reactive T cells.
Alexander J. Dwyer, Zachary R. Shaheen, Brian T. Fife   +2 more
doaj   +1 more source

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]

, 1988
Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A, Coppel, R, Gershwin, M, Leung, P, Van De Water, Judith   +4 more
core