Antigen-specific T cell responses in autoimmune diabetes
Frontiers in ImmunologyAutoimmune diabetes is a disease characterized by the selective destruction of insulin-secreting β-cells of the endocrine pancreas by islet-reactive T cells.
Alexander J. Dwyer +2 more
doaj +1 more source
Advancements in multiple sclerosis
Internal Medicine Journal, EarlyView.Abstract The global prevalence of multiple sclerosis (MS) is increasing, and early diagnosis and treatment is essential in mitigating disability. While recent therapeutic advancements have significantly reduced relapse rates, the progressive and degenerative aspects of MS continue to pose major challenges.
Turlough Montague +3 more
wiley +1 more source
Autoimmunity against cytokines: Double strike in autoimmune disease, a historical perspective
Biomédica: revista del Instituto Nacional de SaludAutoimmune responses are characterized by the development of antibodies and the activation of T lymphocytes against self-antigens. This leads to an effector immune response against tissues expressing antigens, which are later recognized by the host ...
Iván Insignares +6 more
doaj +1 more source
The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase. [PDF]
, 1988 Autoantibodies to mitochondrial antigens are characteristic of the autoimmune liver disease primary biliary cirrhosis (PBC), but the precise antigenic determinants recognized by these antibodies have not been defined.
Ansari, A +4 more
core
Bibliometric Analysis of the 50 Most Cited Publications in Epidermolysis Bullosa
Pediatric Dermatology, EarlyView.ABSTRACT Epidermolysis bullosa (EB) is a group of inherited skin disorders characterized by extreme skin fragility, leading to recurrent blistering and significant impacts on patients' quality of life. A bibliometric analysis of the 50 most‐cited EB articles from the past six decades reveals that the majority of research focuses on understanding EB ...
Evelyn F. Fagan +4 more
wiley +1 more source
Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease [PDF]
Background - Retinal S-antigen (S-Ag) is a most characterized autoantigen of autoimmune uveitis. The recognized immunodominant epitope of human S-Ag in patients with uveitis has not been identified. In this study, we selected certain patients with active
Du, L.P. +6 more
core +2 more sources
Juvenile Dermatomyositis Triggered by Influenza B: A Case Report on Viral‐Induced Autoimmunity
Pediatric Dermatology, EarlyView.ABSTRACT A previously healthy 13‐year‐old boy developed juvenile dermatomyositis (JDM) shortly after a confirmed influenza B infection, presenting with progressive proximal muscle weakness and classic cutaneous findings. Laboratory tests revealed elevated muscle enzymes and myositis‐specific autoantibodies, supporting the diagnosis.
Santiago Dans‐Caballero +4 more
wiley +1 more source
EMBO Molecular Medicine, 2017 Several lines of evidence indirectly suggest that antigenic stimulation through the B‐cell receptor (BCR) supports chronic lymphocytic leukemia (CLL) development.
Nereida Jiménez de Oya +12 more
doaj +1 more source
Exploration of the blocking effect of Fab fragment of IgG autoantibody on erythrocyte autoantigens
Zhongguo shuxue zazhiObjective To use Fab segments of autoantibodies to bind to autoantigens on red blood cells in order to block the binding of intact autoantibodies to the autoantigens.
Haitao HUANG, Xuehong WEN
doaj +1 more source
Pyoderma gangrenosum and spider bites: a case series
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Luca Rapparini +6 more
wiley +1 more source