Results 141 to 150 of about 59,330 (297)

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Kikuchi‐Fujimoto disease: investigating comprehensive clinicopathological features and risk factors for recurrence

Histopathology, Volume 87, Issue 1, Page 68-80, July 2025.
Comprehensive clinicopathological analysis of 112 cases of Kikuchi‐Fujimoto disease (KFD) was conducted, and offered insights into recurrence risk factors and histopathological patterns. Recurrent KFD may fall between transient KFD and overt autoimmune disorders and lead to a better understanding of the aetiology of KFD.
Midori Filiz Nishimura, Chikako Sakao, Yuka Kurokawa, Yoshito Nishimura, Asami Nishikori, Hidetaka Yamamoto, Yasuharu Sato   +6 more
wiley   +1 more source

Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjögren’s syndrome

Autoimmunity, 2019
Salivary and lacrimal gland involvement is a characteristic feature of primary Sjögren’s syndrome (pSS), where tissue destruction is mediated by mononuclear cell infiltration, resulting in lacrimal and salivary gland impairment.
Kathrine Skarstein, Janicke Liaaen Jensen, Hilde Galtung, Roland Jonsson, Karl Brokstad, Lara A. Aqrawi   +5 more
doaj   +1 more source

Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance

Immunological Reviews, Volume 332, Issue 1, July 2025.
ABSTRACT Thymic dendritic cells (DCs) are critical mediators of central tolerance, cooperating with medullary thymic epithelial cells (mTECs) and B cells to establish T‐cell self‐tolerance to the proteome. The DC compartment is highly heterogeneous and is comprised of three major subsets, plasmacytoid dendritic cells (pDCs) and two conventional ...
Aparna Calindi, Lauren I. R. Ehrlich
wiley   +1 more source

Key autoantigens in SLE [PDF]

Rheumatology, 2005
G. Riemekasten, B. H. Hahn
openaire   +3 more sources

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

JOR SPINE, Volume 8, Issue 2, June 2025.
Within this manuscript, bioinformatics and experimental methods are used to explore the role of circadian rhythm and immunity in Intervertebral Disc Degeneration (IVDD). CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI were successfully demonstrated to be hub rhythm‐related genes in the process of IVDD together with immunity.
Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang   +5 more
wiley   +1 more source

Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip

, 2006
Dilated cardiomyopathy (DCM) is a myocardial disease characterized by progressive depression of myocardial contractile function and ventricular dilatation.
Cahill, D., Felix, S., Gutjahr, C., Horn, S., König, A., Landsberger, M., Lehrach, H., Lueking, A., Murphy, D., Schulte, K., Staudt, A.   +10 more
core   +1 more source

Rapid and Sustained Improvement of Lichen Planus Pemphigoides With the JAK1 Inhibitor Upadacitinib

JEADV Clinical Practice, Volume 4, Issue 2, Page 525-528, June 2025.
ABSTRACT Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disorder characteris ed by lichenoid plaques and blister formation. Current treatments are often ineffective, and there is a lack of standardised guidelines. The disease's pathogenesis involves both T‐cell‐mediated lichenoid dermatitis and autoantibody formation, presenting ...
Louise Gueissaz, Ronald Wolf, Christoph Schlapbach   +2 more
wiley   +1 more source

ファージディスプレイ法による自己免疫疾患の自己抗原の探索 [PDF]

, 2018
筑波大学 (University of Tsukuba ...
Niwa Mikio, 丹羽 幹夫
core   +2 more sources