Results 21 to 30 of about 64,232 (366)
Nature Communications, 2020 The presence of antiendothelial cell antibodies (AECAs) has been documented in Takayasu arteritis (TAK), a chronic granulomatous vasculitis. Here, we identify cell-surface autoantigens using an expression cloning system.
Tomoyuki Mutoh +11 more
semanticscholar +1 more source
Neoepitopes in Type 1 Diabetes: Etiological Insights, Biomarkers and Therapeutic Targets
Frontiers in Immunology, 2021 The mechanisms underlying type 1 diabetes (T1D) pathogenesis remain largely unknown. While autoantibodies to pancreatic beta-cell antigens are often the first biological response and thereby a useful biomarker for identifying individuals in early stages ...
Teresa Rodriguez-Calvo +3 more
doaj +1 more source
Diagnostics, 2023 Background: COVID-19 is a heterogenous disease resulting in long-term sequela in predisposed individuals. It is not uncommon that recovering patients endure non-respiratory ill-defined manifestations, including anosmia, and neurological and cognitive ...
Yael Lavi +11 more
doaj +1 more source
Ribonucleoprotein complexes as autoantigens [PDF]
Current Opinion in Immunology, 1995 Many intracellular proteins and nucleic acids, that are involved in important biosynthetic pathways, are targeted by autoantibodies occurring spontaneously in the sera of patients with systemic autoimmune diseases. Frequently, the autoantigens are assembled into multicomponent complexes containing both nucleic acid(s) and proteins.
Venrooij, W.J. van, Pruijn, G.J.M.
openaire +4 more sources
Molecular & Cellular Proteomics, 2020 Lung cancer (LC) remains the leading cause of mortality from malignant tumors worldwide. To identify biomarkers for early detection of LC, we employed the HuProt array platform and ELISA tests to identify and validate for IgA-bound autoantigens, which ...
Jianbo Pan +11 more
semanticscholar +1 more source
Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. [PDF]
, 2016 High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemokine ...
Baechler, Emily C +10 more
core +2 more sources
Clinical Case Reports, 2020 A blunt trauma to a phthisical eye may elicit sympathetic ophthalmia. Non invasive imaging such as use of optical coherence tomography and angiography metrics of the retinal and choroidal vasculature can help monitor response to the treatment.
Anadi Khatri +6 more
doaj +1 more source
, 2011 Objective This study was conducted with sera from patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and arthritis and lupus-like disease animal models to identify innate immune system-dependent and -independent ...
Burmester, G. +5 more
core +2 more sources
Equine recurrent uveitis - A spontaneous horse model of uveitis [PDF]
, 2008 Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis.
Altmann, Frank +8 more
core +1 more source
Frontiers in Immunology, 2019 The etiopathologies behind autoimmune thyroid diseases (AITDs) unravel misbehavior of immune components leading to the corruption of immune homeostasis where thyroid autoantigens turn foe to the self.
Safikur Rahman +6 more
doaj +1 more source