Results 51 to 60 of about 49,748 (241)

Genetics and Omics Analysis of Autoimmune Skin Blistering Diseases

Frontiers in Immunology, 2019
Autoimmune blistering diseases (AIBDs) of the skin are characterized by autoantibodies against different intra-/extracellular structures within the epidermis and at the basement membrane zone (BMZ). Binding of the antibodies to their target antigen leads
Michael Olbrich, Michael Olbrich, Axel Künstner, Axel Künstner, Mareike Witte, Hauke Busch, Hauke Busch, Anke Fähnrich, Anke Fähnrich   +8 more
doaj   +1 more source

The relationship between chronic immune response and neurodegenerative damage in long COVID-19

Frontiers in Immunology, 2022
In the past two years, the world has faced the pandemic caused by the severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2), which by August of 2022 has infected around 619 million people and caused the death of 6.55 million individuals globally ...
José Pedro Elizalde-Díaz, Clara Leticia Miranda-Narváez, Juan Carlos Martínez-Lazcano, Eduardo Martínez-Martínez   +3 more
doaj   +1 more source

Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]

, 2018
The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć, Kamila Kozłowska, Marta Ząbczyńska   +2 more
core   +1 more source

Immune system markers of neuroinflammation in patients with clinical diagnose of neuromyelitis optica Marcadores imunológicos em pacientes com diagnóstico de neuromielite óptica

Arquivos de Neuro-Psiquiatria, 2008
Neuromyelitis optica (NMO) is an inflammatory, demyelinating disease of the central nervous system characterized by the association of a serious myelitis and unilateral or bilateral optic neuritis.
Soniza Vieira Alves-Leon, Maria Lucia Vellutini Pimentel, Gabrielle Sant'Anna, Fabíola Rachid Malfetano, Cláudio Duque Estrada, Thereza Quirico- Santos   +5 more
doaj   +1 more source

Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application [PDF]

, 2016
Background The insulinoma associated protein tyrosine phosphatase 2 (IA-2) is one of the immunodominant autoantigens involved in the autoimmune attack to the beta-cell in Type 1 Diabetes Mellitus.
A Trabucchi, A Trabucchi, A Trabucchi, A Villalba, A Villalba, A Westerlund-Karlsson, Adriana Victoria Sabljic, AG Krochik, AL Notkins, Aldana Trabucchi, BD Spangler, Bruno David Rovitto, C Levy-Marchal, C Tiberti, C Torn, CA Baer, CC Richardson, CF Verge, D Barford, DU Rabin, DU Rabin, E Bonifacio, E Bonifacio, E Kawasaki, EA Gale, Edgardo Poskus, ELD Harlow, ER LaVallie, ER LaVallie, ET Mambetisaeva, Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, F Baneyx, F Sodoyez-Goffaux, G Hannig, GS Eisenbarth, H Goetz, H Mziaut, H Mziaut, H Shägger, H Xie, I Kikkas, J Sambrook, J Seissler, J Suckale, JA Berzofsky, JA Berzofsky, JA Dromey, JC Sodoyez, JM Gonzalez-Buitrago, JM Wenzlau, JP Palmer, K Lobner, KT Elvers, L Castano, LL Guerra, Luciano Lucas Guerra, M Hawa, M Knip, M Masuda, M Solimena, M Trajkovski, M Trajkovski, MA Payton, ML Papouchado, ML Papouchado, MP Sica, MS Lan, MS Lan, Natalia Inés Faccinetti, NG Morgenthaler, O Pines, P Tompa, PD Burbelo, PJ Bingley, PZ Zimmet, R Gianani, R Turner, RD Hoffman, RR Stumpo, Ruben Francisco Iacono, S Chen, S Krause, S Schubert, S Torii, Silvina Noemí Valdez, SJ Kim, SLBP Thrower, SN Valdez, SN Valdez, T Ort, T Tuomi, VN Uversky, WA Hagopian, X Jia, X Palomer, Z Zhao   +95 more
core   +5 more sources

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

Frontiers in Immunology, 2019
The mitochondrion supplies energy to the cell and regulates apoptosis. Unlike other mammalian organelles, mitochondria are formed by binary fission and cannot be directly produced by the cell.
Yann Becker, Geneviève Marcoux, Isabelle Allaeys, Anne-Sophie Julien, Renée-Claude Loignon, Hadrien Benk-Fortin, Emmanuelle Rollet-Labelle, Joyce Rauch, Paul R. Fortin, Paul R. Fortin, Paul R. Fortin, Eric Boilard, Eric Boilard   +12 more
doaj   +1 more source

Re-exposure to beta cell autoantigens in pancreatic allograft recipients with pre-existing beta cell autoantibodies [PDF]

, 2015
Re-exposure to beta cell autoantigens and its relevance in the presence of donor-specific antibodies (DSA) in pancreatic allograft recipients is not well known. Thirty-three patients requiring a pancreas transplant were enrolled in an IRB approved study.
Book, Benita, Faiz, Sara, Fridell, Jonathan, Mujtaba, Muhammad Ahmad, Rigby, Mark, Sharfuddin, Asif, Taber, Tim, Wiebke, Eric   +7 more
core   +1 more source

Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens

EMBO Molecular Medicine, 2017
Several lines of evidence indirectly suggest that antigenic stimulation through the B‐cell receptor (BCR) supports chronic lymphocytic leukemia (CLL) development.
Nereida Jiménez de Oya, Marco De Giovanni, Jessica Fioravanti, Rudolf Übelhart, Pietro Di Lucia, Amleto Fiocchi, Stefano Iacovelli, Dimitar G Efremov, Federico Caligaris‐Cappio, Hassan Jumaa, Paolo Ghia, Luca G Guidotti, Matteo Iannacone   +12 more
doaj   +1 more source

Decoding the relationship between cow’s milk proteins and development of type 1 diabetes mellitus [PDF]

Archives of Endocrinology and Metabolism
Objective To analyze in silico the evidence of molecular mimicry between human beta-cell autoantigens and cow’s milk proteins as a potential type 1 diabetes mellitus (T1DM) trigger.
Luís Jesuino de Oliveira Andrade, Gabriela Correia Matos de Oliveira, Luísa Correia Matos de Oliveira, Alcina Maria Vinhaes Bittencourt, Yvana Baumgarth, Luís Matos de Oliveira   +5 more
doaj   +1 more source

Anti-Idiotypic mRNA Vaccine to Treat Autoimmune Disorders

Vaccines, 2023
The 80+ existing autoimmune disorders (ADs) affect billions with little prevention or treatment options, except for temporary symptomatic management, leading to enormous human suffering and a monumental financial burden. The autoantibodies formed in most
Sarfaraz K. Niazi
doaj   +1 more source