Results 51 to 60 of about 24,725 (157)
Microbiota Medicine Research, Volume 1, Issue 2, Page 63-89, June 2026.ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai +6 more
wiley +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang +13 more
wiley +1 more source
Sarcoidosis and Autoinflammation
Inflammation and Regeneration, 2011 Sporadic early-onset sarcoidosis (EOS) and familial Blau syndrome (BS) form a distinct set of autoinflammatory diseases, both of which onset in infancy and show a clinical triad of dermatitis, arthritis and uveitis histologically composed of noncaseating epithelioid cell granuloma.
openaire +2 more sources
Experimental Dermatology, Volume 35, Issue 4, April 2026.ABSTRACT Hidradenitis suppurativa (HS) is an autoinflammatory keratinisation disease affecting the pilosebaceous unit and hallmarked by a complex and multifactorial pathogenesis. Although genomic and transcriptomic investigations have substantially advanced our understanding of key mechanisms underlying HS pathogenesis, proteomic studies remain limited,
Chiara Moltrasio +9 more
wiley +1 more source
Sterile osteomyelitis: a cardinal sign of autoinflammation
Autoinflammatory bone disorders (ABDs) are characterized by sterile bone inflammation stemming from dysregulated innate immune responses. This review focuses on the occurrence of sterile osteomyelitis in ABDs and related diseases, notably chronic ...
Tiago Borges +2 more
core +1 more source
Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation
, 2023 Unlike other nucleotide oligomerization domain-like receptors, Nlrp10 lacks a canonical leucine-rich repeat domain, suggesting that it is incapable of signal sensing and inflammasome formation.
Hodgetts, Ryan James +29 more
core +1 more source
ACR Open Rheumatology, Volume 8, Issue 3, March 2026.Objective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Austen Grooms +3 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 3, March 2026.Objective Systemic lupus erythematosus (SLE) is an autoimmune disease that affects numerous organs. Neutrophil extracellular traps (NETs) contribute to sterile inflammation and autoantibody generation in SLE. Isolevuglandins (isoLGs) are reactive oxygen species that are formed during NETosis and contribute to chromatin expansion.
Jaya Krishnan +7 more
wiley +1 more source
Autoimmunity, autoinflammation and kidney
Clinical pharmacology and therapy, 2022 Systemic autoimmune and autoinflammatory disease are associated with all types of diffuse kidney disease, that is, glomerulonephritis (including rapidly progressive), thrombotic microangiopathy, tubulointerstitial nephritis, and AA-amyloidosis. However, the occurrence and types of nephropathies differ significantly in patients with various systemic ...
N. Bulanov, S. Moiseev
openaire +1 more source
British Journal of Haematology, Volume 208, Issue 3, Page 819-828, March 2026.Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff +3 more
wiley +1 more source