Results 61 to 70 of about 24,492 (179)

The Multifaceted Role of Pyroptosis: Molecular Mechanisms, Crosstalk with Other Cell Death Pathways, and Therapeutic Implications

MedComm, Volume 7, Issue 7, July 2026.
Pyroptosis maintains immune homeostasis by eliminating damaged or infected cells, but its dysregulation promotes inflammation and cancer progression. The diagram illustrates key activation pathways, links with other programmed cell deaths, and cancer‐specific effects, enhancing its dual protective and pathogenic roles.
Diego Liviu Boaru, Patricia De Castro‐Martinez, Cielo Garcia‐Montero, Oscar Fraile‐Martinez, Majd N. Michael Alhaddadin, Silvestra Barrena‐Blázquez, Laura Lopez‐Gonzalez, Clara Tasende Fernández, Ricardo Alvarado‐Hurtado, Tomás Ratia Giménez, Inmaculada Lasa‐Unzúe, Manuel Díez Alonso, Alberto Gutiérrez‐Calvo, Miguel A. Saez, David Cobo‐Prieto, Jose V. Saz, Melchor Alvarez‐Mon, Raul Diaz‐Pedrero, Miguel A. Ortega   +18 more
wiley   +1 more source

Insights Into the Susceptibility of Fungal Infection and STAT3 Genetic Mutations

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a key transcription factor that regulates a spectrum of genes and signalling pathways critical for the antifungal immune response. Mutations in the STAT3 gene confer susceptibility to severe and recurrent fungal infections, predominantly via disruption of interleukin‐17 (IL‐17 ...
Fengming Li, Xiaodong Liu, Yuanyuan Li, Jie Wu, Ningning Dang, Jing Guo   +5 more
wiley   +1 more source

Candida oesophagitis as an Initial Manifestation of VEXAS Syndrome: Expanding Evidence for an Acquired Immunodeficiency Phenotype

eJHaem, Volume 7, Issue 4, August 2026.
Demi Rianne Vintges, Marina Weerheim, Faiz Karim   +2 more
wiley   +1 more source

Distinct Pattern of Atypical Megakaryocytes in VEXAS Syndrome

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 713-714, August 2026.
Andrew Y. Sung, Jackson W. Douglas, Olga K. Weinberg, Sharon K. Germans, Weina Chen   +4 more
wiley   +1 more source

Autoinflammation [PDF]

Zeitschrift für Rheumatologie, 2012
P. Lamprecht, R.E. Schmidt
openaire   +1 more source

Micrornas in autoinflammation and autoimmunity [PDF]

Pediatric Rheumatology, 2014
Micro(mi)RNAs are small non-coding RNAs that play critical roles in physiological networks by regulating genetic programs. They are conserved from worms to mammals and function as negative regulators of protein-encoding gene expression. Research on the role of miRNAs in pathophysiological conditions is very active since 10 years and several works ...
openaire   +1 more source

Modern concept of autoimmunity in rheumatology

Научно-практическая ревматология, 2018
Two fundamental pathologic processes are central to the spectrum of chronic inflammation mechanisms: autoimmunity and autoinflammation.  Autoimmunity and autoinflammation are mutually potent pathologic processes; their development is considered within ...
E. L. Nasonov
doaj  

Autoinflammation in der Dermatologie [PDF]

hautnah, 2017
Autoinflammatorische Syndrome sind seltene, meist monogenetisch bedingte Uberreaktionen des angeborenen Immunsystems, im Speziellen von Monozyten und Makrophagen (dies ist ein Gegensatz zur Autoimmunitat, bei der antigenspezifische Vertreter des erworbenen Immunsystems aktiv sind: T‑Zellen, B‑Zellen). Die Ursache liegt oft im sog. Inflammasom. Dies ist
openaire   +1 more source

Cholesterol-embolization syndrome: current perspectives

Vascular Health and Risk Management, 2019
Abdullah OzkokDepartment of Internal Medicine and Nephrology, Memorial Şişli Hospital, Istanbul, TurkeyAbstract: Cholesterol-embolization syndrome (CES) is a multisystemic disease with various clinical manifestations.
Ozkok A
doaj  

Autoinflammation behind the curtain [PDF]

British Journal of Dermatology, 2018
Navarini, A. A., French, L. E.
openaire   +4 more sources