Results 11 to 20 of about 157,940 (239)

Long-Term Outcomes of Behçet’s Syndrome-Related Uveitis: A Monocentric Italian Experience

Mediators of Inflammation, 2020
Objectives. To examine demographic and clinical characteristics and long-term visual outcome in a cohort of Italian patients affected by Behçet’s uveitis (BU). Materials and Methods.
Jurgen Sota, Luca Cantarini, Antonio Vitale, Arianna Sgheri, Stefano Gentileschi, Valeria Caggiano, Viviana Gelardi, Bruno Frediani, Gian Marco Tosi, Claudia Fabiani   +9 more
doaj   +1 more source

Immune dysregulation as a cause of autoinflammation in fragile X premutation carriers: link between FMRI CGG repeat number and decreased cytokine responses. [PDF]

, 2014
BackgroundIncreased rates of autoinflammatory and autoimmune disorders have been observed in female premutation carriers of CGG repeat expansion alleles of between 55-200 repeats in the fragile X mental retardation 1 (FMR1) gene.
Ashwood, Paul, Berman, Robert F, Careaga, Milo, Hagerman, Randi, Rose, Destanie, Tassone, Flora   +5 more
core   +7 more sources

Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease

Mediators of Inflammation, 2020
Background. Interleukin-1 inhibition has revealed to be a successful treatment approach for patients with adult-onset Still’s disease (AOSD). However, real-life experience is focused on the use of anakinra, while data about canakinumab (CAN) are mainly ...
Antonio Vitale, Virginia Berlengiero, Jurgen Sota, Luisa Ciarcia, Nicola Ricco, Sara Barneschi, Mariam Mourabi, Giuseppe Lopalco, Chiara Marzo, Francesca Bellisai, Florenzo Iannone, Bruno Frediani, Luca Cantarini   +12 more
doaj   +1 more source

Autoinflammatory Bone Diseases [PDF]

Rheumatic Disease Clinics of North America, 2013
Autoinflammatory bone disease is a new branch of autoinflammatory diseases caused by seemingly unprovoked activation of the innate immune system leading to an osseous inflammatory process. The inflammatory bone lesions in these disorders are characterized by chronic inflammation that is typically culture negative with no demonstrable organism on ...
Sara M, Stern, Polly J, Ferguson
openaire   +2 more sources

Autoinflammatory Diseases

Medicina, 2018
This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms ...
Rigante D., Vitale A., Cantarini L.
  +9 more sources

Autoinflammatory Diseases in Childhood

Balkan Medical Journal, 2020
Autoinflammatory diseases are characterized by recurrent fevers and clinical findings of impaired natural immunity and can involve various organ systems. The concept of autoinflammatory disease emerged after the definition of familial Mediterranean fever
Mehmet Yıldız, Fatih Haşlak, Amra Adrovic, Kenan Barut, Özgür Kasapçopur   +4 more
doaj   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Designation of Autoinflammatory Skin Manifestations With Specific Genetic Backgrounds

Frontiers in Immunology, 2020
“Autoinflammatory disease (AiD)” has first been introduced in 1999 when the responsible gene for the familial Hibernean fever or autosomal dominant-type familial Mediterranean fever-like periodic fever syndrome was reportedly identified as tumor necrosis
Nobuo Kanazawa
doaj   +1 more source

Autoinflammatory diseases: what’s behind them and what’s new. A review

Dermatology Reports, 2022
Autoinflammatory diseases are characterized by bouts of systemic or localized inflammation in the absence of an infection. While some autoinflammatory diseases are caused by a single gene mutation, others have been shown to be multifactorial, involving ...
Michele Maalouly, Serena Saade, Mazen Kurban   +2 more
doaj   +1 more source

Autoimmune and autoinflammatory mechanisms in uveitis [PDF]

, 2014
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
A Amadi-Obi, A Arida, A Cortes, A Fox, A Jager, A Peters, A Rothova, AC Anderson, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AG Commodaro, AG Commodaro, AJ St. Leger, AK Denniston, AK Denniston, AL Oberg, Andrew D. Dick, B Bodaghi, B Engelhardt, BJ Raveney, BJ Raveney, BJ Raveney, BS Sheridan, C Broderick, C Terrada, C-C Chan, CC Murphy, CEI Janssen, Chi-Chao Chan, CJ Calder, CJ Chu, CJ Chu, D Atan, D Atan, D Atan, D Atan, D Banerjee, D Luger, D Perra, DA Carter, DA Copland, DA Copland, DA Copland, DA Copland, DA Jabs, DC Wraith, DF Martin, DJ Hankey, DJ Kilmartin, DL Turner, E Furusato, EB Gouveia, EC Kerr, EC Kerr, ED Mandelcorn, EF Foxman, EF Remmers, EJ Wherry, F An, F Chen, G Geri, GJ Wright, GJ Wright, GR Wallace, H Keino, H Mielants, H. Nida Sen, HL Rosenzweig, HL Rosenzweig, HL Rosenzweig, HM Cherwinski, HN Sen, IJ Crane, J Bauer, J Candia, J Chen, J Correale, JA Todd, JB Fordham, JC Wei, JF Bach, JJ Kuiper, JP Sherlock, JT Rosenbaum, JV Forrester, JV Forrester, JV Forrester, JV Forrester, K Gocho, KG Anderson, KH Sonoda, KM Murphy, KM Murphy, L Jostins, L Mao, Lai Wei, Lindsay B. Nicholson, LK Grange, LK Mackay, LM Wakim, LM Wakim, LP Schewitz, LV Rizzo, M Chen, M Cordero-Coma, M Deckert, M Greter, M Khairallah, M Pepper, MC Jenmalm, MG Netea, MJ Mattapallil, MJ Robertson, MS Suttorp-Schulten, N Hashida, N Mizuki, N Taylor, N Yosef, NA Rao, O Tomkins-Netzer, P Kivisäkk, P Yang, P Zamiri, PA Kurz, PB Medawar, PP Sfikakis, R Banchereau, R Gold, R Plumlee Courtney, R Ramesh, R Shechter, R Zhang, R Zhou, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, Richard W. Lee, RJ Snelgrove, RK Agarwal, RM Hoek, Robert B. Nussenblatt, RP Nair, RR Caspi, RR Caspi, RR Caspi, RR Caspi, RW Darrell, RW Lee, RW Lee, RW Lee, RW Read, RW Read, S Horie, S Hou, S Hou, S Jawad, S Ohno, S Ooka, S Preston, S Sugita, S Sugita, S Sugita, S Sugita, S Yeh, S Zhang, SA Ramsey, SB Su, SC Bendall, SC Teoh, SJ Morrison, SL Masters, SM Islam, SM Sharma, SM Whitcup, SR Boyd, SR Taylor, SR Thurau, SR Thurau, SW McPherson, T Lambe, T Yoshimura, TA Manolio, TM Martin, U Kaufmann, VL Calder, W Chi, W Chi, WF Hickey, WW Soon, Y Fei, Y Kirino, Y Okunuki, Y Peng, Y Usui, YH Lee, Z Li, Z Tu   +203 more
core   +1 more source