Results 21 to 30 of about 5,018,411 (238)
Genetic diagnosis of autoinflammatory disease patients using clinical exome sequencing [PDF]
, 2023 Autoinflammatory diseases comprise a wide range of syndromes caused by dysregulation of the innate immune response. They are difficult to diagnose due to their phenotypic heterogeneity and variable expressivity.
Casals López, Ferran +5 more
core +2 more sources
Cellular models in autoinflammatory disease research. [PDF]
Clin Transl ImmunologySystemic autoinflammatory diseases are a heterogeneous group of rare genetic disorders caused by dysregulation of the innate immune system. Understanding the complex mechanisms underlying these conditions is critical for developing effective treatments ...
Şen B, Balcı-Peynircioğlu B.
europepmc +2 more sources
An Update on Autoinflammatory Diseases [PDF]
Current Medicinal Chemistry, 2013 Autoinflammatory diseases area group of clinical conditions other than autoimmune diseases, characterized by recurrent inflammatory episodes. From apathogenetic point of view they are determined by a dys regulation of innate immunity, without involvement of specific immunity (auto reactive T cells and auto antibodies). Recently, the increased knowledge
Ciccarelli F +2 more
openaire +3 more sources
Monogenic autoinflammatory diseases [PDF]
Rheumatology, 2014 During the past 15 years, a growing number of monogenic inflammatory diseases have been described and their respective responsible genes identified. The proteins encoded by these genes are involved in the regulatory pathways of inflammation and are mostly expressed in cells of the innate immune system.
Ricardo A G, Russo, Paul A, Brogan
openaire +2 more sources
Orvosi hetilap, 2018 This book discusses the role of the microbiome in rheumatic diseases and details its implications for patient treatment. Recently, with technological advances, there has been significant research into the microbiome. This has enabled us to more profoundly understand its role in our immune system maturation as well as the role played by microorganisms ...
Rigante D., Vitale A., Cantarini L.
+9 more sources
Diagnosis and treatment of autoinflammatory diseases in adults: a clinical approach from rheumatologists [PDF]
, 2019 utoinflammatory diseases are characterized by recurrent systemic inflammation due to dysfunction of the innate immune system, and they are originally the hereditary recurrent fever syndromes that develop in early childhood. Many cases are thus diagnosed
Koga, Tomohiro, Kawakami, Atsushi
core +1 more source
A clinical review of autoinflammatory diseases and Behcet's disease: Classification, pathogenesis and treatment [PDF]
, 2020 Behcet’s disease is a rheumatic disease with oral aphthae, genital aphthae, arthritis and vasculitis. Studies about its pathogenesis have increased and is thought to be one of the autoinflammatory diseases in recent years.
Aksakal, Sengul
core +1 more source
Autoinflammatory keratinization diseases [PDF]
Journal of Allergy and Clinical Immunology, 2017 ファイル公開：2018-12 ...
Akiyama, Masashi +3 more
openaire +3 more sources
Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]
, 2010 The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J +59 more
core +1 more source
Swiss Medical Weekly, 2012 The monogenic autoinflammatory syndromes are conditions caused by mutations of genes coding for proteins that play a pivotal role in the regulation of the inflammatory response. Due to their genetic nature, most of these disorders have an early onset.
S Federici, R Caorsi, M Gattorno
openaire +4 more sources