Results 31 to 40 of about 157,940 (239)
Immunology Letters, 2014 Autoinflammatory diseases represent an expanding spectrum of genetic and non-genetic inflammatory diseases characterized by recurrent episodes of fever and systemic inflammation affecting the eyes, joints, skin, and serosal surfaces. Thus, these syndromes are recognized as disorders of innate immunity.
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Autoinflammatory diseases [PDF]
Clinical pharmacology and therapy, 2020 Autoinflammatory diseases are a group of disorders caused by a dysregulation of the innate immune system. Unlike autoimmune diseases, they are not associated with changes in humoral or cellular immunity. The authors review the current classification, clinical manifestations and treatment of various systemic autoinflammatory diseases, including ...
V.V. Rameev +3 more
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Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases [PDF]
, 2017 At the population level, rheumatoid arthritis (RA) is generally viewed as autoimmune in nature with a small subgroup of cases having a palindromic form or systemic autoinflammatory disorder (SAID) phenotype.
Barcenas-Morales, G +6 more
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Frontiers in Neurology, 2022 Macrophages play important roles in tissue homeostasis and inflammation. Recent studies have revealed that macrophages are dispersed in the inner ear and may play essential roles in eliciting an immune response.
Toru Miwa, Toru Miwa, Takayuki Okano
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Galantamine attenuates autoinflammation in a mouse model of familial mediterranean fever
Molecular Medicine, 2022 Background Autoinflammatory diseases, a diverse group of inherited conditions characterized by excessive innate immune activation, have limited therapeutic options.
Ibrahim T. Mughrabi +10 more
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Insights into Imaging, 2020 Purpose 1. To review the contemporary literature and present a list of the imaging findings for patients with autoinflammatory diseases from our hospital. All these patients are found to have a genetic mutation that is responsible for their disease.
Alaa N. Alsharief +6 more
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Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]
, 2018 Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D. +2 more
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RMD Open, 2022 Objectives Besides adaptive immunity genes, genetic risk factors for psoriatic arthritis (PsA) include innate immunity loci, which suggests an autoinflammatory disease mechanism, at least in a subset of patients.
Torsten Witte +5 more
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GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever [PDF]
, 2018 Pyroptosis is an inflammasome-induced lytic cell death mode, the physiological role of which in chronic inflammatory diseases is unknown. Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide, affecting an ...
Chi, Hongbo +11 more
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The burgeoning field of innate immune-mediated disease and autoinflammation. [PDF]
, 2016 Immune-mediated autoinflammatory diseases are occupying an increasingly prominent position among the pantheon of debilitating conditions that afflict mankind.
McDermott, MF +3 more
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