Results 51 to 60 of about 148,918 (213)

Axial spondyloarthritis in patients with recurrent fever attacks: data from the AIDA network registry for undifferentiated autoInflammatory diseases (USAIDs)

Frontiers in Medicine, 2023
BeckgroundDespite the recent advances in the field of autoinflammatory diseases, most patients with recurrent fever episodes do not have any defined diagnosis.
Antonio Vitale, Antonio Vitale, Valeria Caggiano, Valeria Caggiano, Isabel Silva, Daniel G. Oliveira, Daniel G. Oliveira, Piero Ruscitti, Francesco Ciccia, Ibrahim Vasi, Abdurrahman Tufan, Giuseppe Lopalco, Ibrahim A. AlMaghlouth, Jurgen Sota, Jurgen Sota, Ewa Wiesik-Szewczyk, Carla Gaggiano, Carla Gaggiano, Henrique Ayres Mayrink Giardini, Veronica Spedicato, Gaafar Ragab, Gaafar Ragab, Florenzo Iannone, Alberto Balistreri, Micol Frassi, José Hernández-Rodríguez, Claudia Fabiani, Claudia Fabiani, Paolo Falsetti, Paolo Falsetti, Nunzia Di Meglio, Nunzia Di Meglio, Bruno Frediani, Bruno Frediani, Maria Antonietta Mazzei, Maria Antonietta Mazzei, Donato Rigante, Donato Rigante, Raquel Faria, Luca Cantarini, Luca Cantarini   +40 more
doaj   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Diagnostic dilemma in autoinflammatory disease in two patients: does the name matter?

The Turkish Journal of Pediatrics, 2013
The systemic autoinflammatory diseases are inflammatory disorders characterized by uncontrolled inflammation of the innate immune system. A common monogenic autoinflammatory disease is familial Mediterranean fever (FMF), associated with mutations ...
Bora Gülhan, Ayşe Büyükcam, Isabelle Touitou, Seza Özen   +3 more
doaj  

Pharmacologic management of renal involvement in monogenic autoinflammatory diseases

European Journal of Medical Research
Kidney involvement represents one of the main targets of the systemic inflammatory process and is underscored by a heterogeneous pathology ranging from amyloidosis to non-amyloid-related damage rooted in inflammasome activation.
Ahmed Fayed, Mohamed Tharwat Hegazy, Jurgen Sota, Carla Gaggiano, Gaafar Ragab   +4 more
doaj   +1 more source

Update on ocular manifestations of the main monogenic and polygenic autoinflammatory diseases

Frontiers in Ophthalmology
Autoinflammatory diseases include disorders with a genetic cause and also complex syndromes associated to polygenic or multifactorial factors. Eye involvement is present in many of them, with different extent and severity.
Alex Fonollosa, Alex Fonollosa, Ester Carreño, Ester Carreño, Antonio Vitale, Ankur K. Jindal, Athimalaipet V. Ramanan, Laura Pelegrín, Borja Santos-Zorrozua, Verónica Gómez-Caverzaschi, Luca Cantarini, Claudia Fabiani, José Hernández-Rodríguez   +12 more
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Dry eye disease and spondyloarthritis: expanding the spectrum of systemic inflammatory disorders associated with ocular surface disease. Data from the international AIDA Network Spondyloarthritis Registry

Frontiers in Medicine
ObjectiveDry eye disease (DED) is a condition associated with a myriad of systemic disorders. According to recent preliminary data, axial spondylarthritis (axial-SpA) could represent a new entity associated with DED. Therefore, this study aimed to assess
Antonio Vitale, Antonio Vitale, Valeria Caggiano, Valeria Caggiano, Eduardo Martín-Nares, Nunzia Di Meglio, Nunzia Di Meglio, Cristian Sica, Cristian Sica, Andrea Hinojosa-Azaola, Maria Orsetta Perfetti, Maria Orsetta Perfetti, Alessandra Pagliara, Alessandra Pagliara, Giorgia Guidetti, Giorgia Guidetti, Alex Fonollosa, Roberta Lopez, Roberta Lopez, Jessica Sbalchiero, Jessica Sbalchiero, Jurgen Sota, Jurgen Sota, Ester Carreño, Ester Carreño, Perla Ayumi Kawakami-Campos, Stefano Gentileschi, Stefano Gentileschi, Alejandra de-la-Torre, Gian Marco Tosi, Gian Marco Tosi, Maria Antonietta Mazzei, Maria Antonietta Mazzei, Alberto Balistreri, Alberto Balistreri, Bruno Frediani, Bruno Frediani, Luca Cantarini, Luca Cantarini, Claudia Fabiani, Claudia Fabiani   +40 more
doaj   +1 more source

Childhood versus adulthood-onset autoinflammatory disorders: myths and truths intertwined

Reumatismo, 2013
Autoinflammatory disorders are characterized by spontaneous episodes of systemic inflammation deriving from inherited defects of the innate immune system.
L. Cantarini, A. Vitale, O.M. Lucherini, I. Muscari, F. Magnotti, G. Brizi, B. Frediani, G.D. Sebastiani, M. Galeazzi, D. Rigante   +9 more
doaj   +1 more source

High‐ and Ultra‐High‐Frequency Ultrasound Identifies a Subclinical Link Between Suppurative Comedonal Nevus and Hidradenitis Suppurativa

Journal of Ultrasound in Medicine, EarlyView.
Suppurative nevus comedonicus (SNC) is a variant of nevus comedonicus in which the characteristic features coexist with recurrent inflammatory lesions that clinically resemble those of hidradenitis suppurativa (HS). We present the ultrasound characteristics of this entity and emphasize the value of high‐resolution dermatologic ultrasound both as a ...
Marta Ivars, Katia Henostroza, Fabià Torres‐Betato, Eva Vilarrasa, Ximena Wortsman   +4 more
wiley   +1 more source

Pathogenic implications, incidence, and outcomes of COVID-19 in autoimmune inflammatory joint diseases and autoinflammatory disorders

Advances in Rheumatology, 2021
As the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly, there are still many unresolved questions of how this virus would impact on autoimmune inflammatory ...
Piero Ruscitti, Alessandro Conforti, Paola Cipriani, Roberto Giacomelli, Marco Tasso, Luisa Costa, Francesco Caso   +6 more
doaj   +1 more source