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Autologous Chondrocyte Implantation [PDF]
JBJS Essential Surgical Techniques, 2016 Autologous chondrocyte implantation (ACI) for the treatment of articular cartilage lesions of the knee joint provides successful and durable long-term outcomes.Obtain standing radiographs and magnetic resonance imaging (MRI) scans to identify all associated abnormalities (background factors).Evaluate the knee joint systematically and harvest cartilage ...
Tom, Minas, Takahiro, Ogura, Tim, Bryant
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Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation (HD-ACI)
Bioengineering, 2023 Hyaline cartilage’s inability to self-repair can lead to osteoarthritis and joint replacement. Various treatments, including cell therapy, have been developed for cartilage damage.
Pedro Guillén-García +9 more
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Chondrocyte De-Differentiation: Biophysical Cues to Nuclear Alterations
Cells, 2022 Autologous chondrocyte implantation (ACI) is a cell therapy to repair cartilage defects. In ACI a biopsy is taken from a non-load bearing area of the knee and expanded in-vitro.
Noor A. Al-Maslamani +6 more
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Journal of Medical Case Reports, 2012 Introduction Matrix-assisted autologous chondrocyte implantation is a well-known procedure for the treatment of cartilage defects, which aims to establish a regenerative milieu and restore hyaline cartilage.
Beyzadeoglu Tahsin +2 more
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High impact sport after autologous chondrocyte implantation in the knee
Orthopaedic Journal of Sports Medicine, 2017 Aims and Objectives: Matrix-based autologous chondrocyte implantation is a well-established treatment for full cartilage defects. When to resume to high impact sports after matrix-based autologous chondrocyte implantation is controversial.
Peter E. Müller Prof. Dr. med. +3 more
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Journal of Orthopaedic Surgery and Research, 2021 Background This study presents patient-reported outcome measures after combined matrix-associated autologous chondrocyte implantation and autologous bone grafting in high-stage osteochondral lesions of the talus in adolescents.
Daniel Körner +5 more
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Regenerative Therapy, 2019 Discoid lateral meniscus tear leads to large chondral defect in the lateral compartment of the knee joint. There are few effective treatments for large chondral defect in both the tibial and femoral sides with severe degenerative lateral meniscus.
Yuki Kato +4 more
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Arthroscopic Autologous Chondrocyte Bone Grafting of a Lateral Tibial Plateau Chondral Defect
Arthroscopy Techniques, 2021 Tibial plateau chondral defects can be difficult to diagnose and treat. Although grafting of femoral and patella chondral defects has become relatively commonplace, the tibial plateau offers unique challenges for some of the grafting techniques used in ...
Steven F. DeFroda, M.D., M.Eng. +5 more
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Optimization strategies for ACI: A step-chronicle review
Journal of Orthopaedic Translation, 2019 Bearing compression from adjacent joints, the articular cartilage is cumulatively pressured in daily life, thus making it prone to injuries; however, once damaged, the self-healing capacity of articular cartilage is limited owing to its low metabolic ...
Yuchen Xiang +3 more
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Arthroscopy Techniques, 2019 Matrix-induced autologous chondrocyte implantation is a 2-stage surgical procedure used to treat symptomatic, full-thickness chondral lesions of the knee.
Kristofer J. Jones, M.D. +1 more
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