Results 21 to 30 of about 9,066 (195)

A new regulator of the Staphylococcus aureus peptidoglycan hydrolase Sle1. [PDF]

PLoS Genetics
Regulation of peptidoglycan hydrolases is crucial for bacterial cell integrity, growth and division. In the bacterial pathogen Staphylococcus aureus, the amidase Sle1 is a key autolysin required for septum splitting and daughter cell separation.
Helena Veiga, Adrian Izquierdo-Martinez, Leonor B Marques, Mariana G Pinho   +3 more
doaj   +2 more sources

Coptis rhizome extract influence on Streptococcus pneumoniae through autolysin activation [PDF]

AMB Express
This study investigated the antibacterial properties of Coptis rhizome, a plant traditionally used for respiratory infections, against Streptoccus pneumonia (S. pneumoniae), for which there has been minimal empirical evidence of effectiveness.
Eon-Bee Lee, Kyubae Lee
doaj   +2 more sources

Inhibiting Peptidoglycan Hydrolase Alleviates MRSA Pneumonia Through Autolysin-Mediated MDP-NOD2 Pathway [PDF]

Infection and Drug Resistance
Yang Yang,1,2 Zongze Yao,1 Jiazhen Zhang,1 Wei Shao,3 Bo Li,2 Huihui Wu,2 Wenjian Tang,3 Jing Zhang2 1School of Medicine, Anhui University of Science and Technology, Huainan, People’s Republic of China; 2Anhui Province Key Laboratory of Occupational ...
Yang Y, Yao Z, Zhang J, Shao W, Li B, Wu H, Tang W, Zhang J   +7 more
doaj   +2 more sources

Characterization of autolysins from Mycobacterium smegmatis [PDF]

Journal of Bacteriology, 1977
This study demonstrates, for the first time, the autolytic enzymes associated with mycobacterial cell walls. Based on the release of radioactivity and ninhydrin-reactive material from isolated cell walls, it was shown that maximum activity occurs during the late log phase of growth and at a buffer pH of about 8.0. Chemical analyses of autolytic digests
J O, Kilburn, G K, Best
openaire   +2 more sources

Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis

Frontiers in Microbiology, 2021
Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network (OLCN) is a novel mechanism of bacterial persistence and immune evasion in chronic osteomyelitis. Previous work highlighted S.
Elysia A. Masters, Elysia A. Masters, Gowrishankar Muthukrishnan, Gowrishankar Muthukrishnan, Lananh Ho, Lananh Ho, Ann Lindley Gill, Karen L. de Mesy Bentley, Karen L. de Mesy Bentley, Karen L. de Mesy Bentley, Chad A. Galloway, Chad A. Galloway, James L. McGrath, Hani A. Awad, Hani A. Awad, Steven R. Gill, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz   +19 more
doaj   +1 more source

From DNA sequence to application: possibilities and complications [PDF]

, 1999
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin, A Bruttin, A Kraus, A Nauta, A Nauta, A Nauta, A Sazicu, AK Aggarwal, B Christiansen, B Christiansen, BC Lokman, BC Lokman, BM Chassy, C Delorme, C Hill, C Schouler, CA Alpert, CA Shearman, CJ Hueck, CO Pabo, CT Verrips, D Botstein, D Lillehaug, D Lillehaug, D Sinderen, DJ O’Sullivan, DJ O’Sullivan, DO Gostick, DO Gostick, E Küster, E Maguin, E Stanley, EJ Luesink, EJ Luesink, EJ Luesink, F Desiere, F Desiere, G Buist, G Buist, G Ramsay, G Vriend, GM Djordjevic, GM Djordjevic, H Brüssow, H Holo, H Neve, I Biswas, J Bardowski, J Bernhardt, J Green, J Law, J Payne, J Stülke, JB Luchansky, JD Boyce, JW Sanders, JW Sanders, JW Sanders, K Chung, K Leenhouts, K Leenhouts, K Leenhouts, K Schnetz, KI Kodaira, KJ Leenhouts, L Dupont, L Dupont, LJ Beamer, LR Garcia, M Curie, M de Guchte, M de Guchte, M Lieb, M Ptashne, MG Johnsen, MJ Gasson, MJ Weickert, MM Sheehan, MW Lubbers, MW Lubbers, N Goupil-Feuillerat, OP Kuipers, P Hals, PG Ruyter, PGGA Ruyter, PL Madsen, PS Chandry, R Parreira, R Schmid, R Young, R Young, RR Raya, S Challou, S Lucchini, S Lucchini, S Simonen, S Spiro, S Spiro, SA Walker, SB Mclvilc, SG Kim, SM Heller, SM Madsen, SR Swindell, T Sasaki, TM Ramseier, V Vagner, WM Vos, WM Vos, WM Vos, Y Fujita   +110 more
core   +3 more sources

Enterococcus faecium Biofilm Formation: Identification of Major Autolysin AtlA_Efm, Associated Acm Surface Localization, and AtlA_Efm-Independent Extracellular DNA Release

mBio, 2013
Enterococcus faecium is an important multidrug-resistant nosocomial pathogen causing biofilm-mediated infections in patients with medical devices. Insight into E.
Fernanda L. Paganelli, Rob J. L. Willems, Pamela Jansen, Antoni Hendrickx, Xinglin Zhang, Marc J. M. Bonten, Helen L. Leavis   +6 more
doaj   +1 more source

Building blocks and blueprints for bacterial autolysins

PLOS Computational Biology, 2021
Bacteria utilize a wide variety of endogenous cell wall hydrolases, or autolysins, to remodel their cell walls during processes including cell division, biofilm formation, and programmed death. We here systematically investigate the composition of these enzymes in order to gain insights into their associated biological processes, potential ways to ...
Spencer J. Mitchell, Deeptak Verma, Karl E. Griswold, Chris Bailey-Kellogg   +3 more
openaire   +4 more sources

Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies [PDF]

, 2013
Daptomycin is an extensively used anti-staphylococcal agent due to the rise in methicillin-resistant Staphylococcus aureus, but the mechanism(s) of resistance is poorly understood.
Jayaswal, Radheshyam K, Rubio, Aileen, Silverman, Jared A, Song, Yang, Wilkinson, Brian J   +4 more
core   +13 more sources

Host and bacterial proteases influence biofilm formation and virulence in a murine model of enterococcal catheter-associated urinary tract infection [PDF]

, 2017
Urinary tract infections: targeting enzymes might help Identifying bacterial and host enzymes that support biofilm formation may help prevent urinary tract infections caused by catheters.
Caparon, Michael G, Cusumano, Zachary T, Flores-Mireles, Ana L, Hultgren, Scott J, Takagi, Enzo, Xu, Wei   +5 more
core   +3 more sources