Results 31 to 40 of about 9,066 (195)
Activity of the major staphylococcal autolysin Atl [PDF]
FEMS Microbiology Letters, 2006 The major autolysin of Staphylococcus aureus (AtlA) and of Staphylococcus epidermidis (AtlE) are well-studied enzymes. Here we created an atlA deletion mutant in S. aureus that formed large cell clusters and was biofilm-negative. In electron micrographs, the mutant cells were distinguished by rough outer cell surface.
Raja, Biswas +5 more
openaire +2 more sources
Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]
, 2020 We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM +10 more
core +4 more sources
Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile
Microbial Cell, 2018 Clostridium difficile, also known as Clostriodioides difficile, is a Gram positive, spore-forming bacterium and a leading cause of antibiotic-associated diarrhea in nosocomial environments. The key virulence factors of this pathogen are two toxins, toxin
Imane El Meouche, Johann Peltier
doaj +1 more source
Potential Roles and Functions of Listerial Virulence Factors during Brain Entry
Toxins, 2020 Although it rarely induces disease in humans, Listeria monocytogenes (Lm) is important due to the frequency of serious pathological conditions—such as sepsis and meningitis—it causes in those few people that do get infected.
Franjo Banović +2 more
doaj +1 more source
PLoS ONE, 2023 Streptococcus pneumoniae is an important cause of fatal pneumonia in humans. These bacteria express virulence factors, such as the toxins pneumolysin and autolysin, that drive host inflammatory responses.
Ηαnnah E Wong +4 more
doaj +1 more source
A new anti-infective strategy to reduce the spreading of antibiotic resistance by the action on adhesion-mediated virulence factors in Staphylococcus aureus. [PDF]
, 2013 Staphylococcus aureus is a flexible microbial pathogen frequently isolated from community-acquired and nosocomial infections. S. aureus expresses a wide array of secreted and cell surface-associated virulence factors, including proteins that promote ...
A. Cellini +7 more
core +1 more source
Lytic transglycosylases: Bacterial space-making autolysins
The International Journal of Biochemistry & Cell Biology, 2008 Lytic transglycosylases are an important class of bacterial enzymes that act on peptidoglycan with the same substrate specificity as lysozyme. Unlike the latter enzymes, however, the lytic transglycosylases are not hydrolases but instead cleave the glycosidic linkage between N-actetylmuramoyl and N-acetylglucosaminyl residues with the concomitant ...
Scheurwater, Edie +2 more
openaire +4 more sources
Pneumonia, 2015 Rapid diagnosis of Streptococcus pneumoniae can play a significant role in decreasing morbidity and mortality of infection. The accurate diagnosis of pneumococcal disease is hampered by the difficulties in growing the isolates from clinical specimens and
Feroze Ahmed Ganaie +2 more
doaj +1 more source
Lysozyme resistance in Streptococcus suis is highly variable and multifactorial. [PDF]
PLoS ONE, 2012 BACKGROUND: Streptococcus suis is an important infectious agent for pigs and occasionally for humans. The host innate immune system plays a key role in preventing and eliminating S. suis infections.
Paul J Wichgers Schreur +5 more
doaj +1 more source
Development of ListeriaBase and comparative analysis of Listeria monocytogenes [PDF]
, 2015 Background: Listeria consists of both pathogenic and non-pathogenic species. Reports of similarities between the genomic content between some pathogenic and non-pathogenic species necessitates the investigation of these species at the genomic level to ...
Ang, Mia Yang +9 more
core +3 more sources