Results 121 to 130 of about 1,031,034 (270)
, 2015 Patch clamp recording in vivo allows an investigator to study intracellular membrane potentials in an intact organism (as opposed to cells in culture or acute brain slices).
David Ferster
core +1 more source
EcoEnergy, EarlyView.Dynamic reconstruction transforms atomically dispersed Cu catalysts into authentic working‐state active phases during CO2 electroreduction. By integrating operando characterization, multiscale simulations, and AI‐assisted predictive modeling, this review establishes a framework for understanding, predicting, and rationally engineering catalyst ...
Jin Liu, Yue‐Wen Fang
wiley +1 more source
β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels
Epilepsia, EarlyView.β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi +8 more
wiley +1 more source
A Comprehensive Review of Fault‐Current Limiter Technologies for Smart and Resilient Power Systems
Energy Science &Engineering, EarlyView.This review compares superconducting, solid‐state, and hybrid fault‐current limiters (FCLs) for modern alternating current, direct current, and hybrid grids. It shows that optimal FCL selection depends on fault characteristics, network configuration, voltage level, protection coordination, and resilience requirements rather than on a universally ...
Abdelrahman Farghly +5 more
wiley +1 more source
Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology. [PDF]
Biol Methods Protoc, 2021 Ng CA +6 more
europepmc +1 more source
Pancreatic α‐cell dysfunction associated with equine insulin dysregulation
Equine Veterinary Journal, EarlyView.Abstract Background Insulin dysregulation (ID) in horses is characterised by insulin resistance and exaggerated insulin responses, yet the underlying endocrine mechanisms remain incompletely understood. In humans, α‐cell dysfunction characterised by exaggerated glucagon secretion contributes to metabolic disease; however, the role of pancreatic α‐cell ...
Sanna Lindåse +3 more
wiley +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Exploration, EarlyView.Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
, 2008 We report on a new type of patch-clamp chip that can simultaneously monitor electrophysiological activity from several individual neurons grown in simple networks.
Py, Christophe +9 more
core +1 more source
Characterization of Compound-Specific, Concentration-Independent Biophysical Properties of Sodium Channel Inhibitor Mechanism of Action Using Automated Patch-Clamp Electrophysiology. [PDF]
Front Pharmacol, 2021 Pesti K +5 more
europepmc +1 more source
Fire and Materials, EarlyView.ABSTRACT The growing demand for flame retardant (FR) polymeric materials has highlighted the need to improve the combustion behaviour of highly flammable polymers such as polyethylene (PE). This study investigates the use of eco‐sustainable mineral FRs as a strategy to reduce heat release and smoke production during combustion, while improving the ...
Linda Vitaloni +3 more
wiley +1 more source