Results 1 to 10 of about 72,646 (143)
The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions [PDF]
eLifeMacroautophagy, a major self-degradation pathway in eukaryotic cells, utilizes autophagosomes to transport self-material to lysosomes for degradation.
Attila Boda +9 more
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Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
Cells, 2022 To maintain homeostasis, cells have evolved stress-response pathways to cope with exogenous and endogenous stress factors. Diverse stresses at high doses may be detrimental, albeit low doses of stress, known as hormesis, can be beneficial.
Mooud Amirkavei +5 more
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Conserved and Diversified Mechanism of Autophagy between Plants and Animals upon Various Stresses
Antioxidants, 2021 Autophagy is a highly conserved degradation mechanism in eukaryotes, executing the breakdown of unwanted cell components and subsequent recycling of cellular material for stress relief through vacuole-dependence in plants and yeast while it is lysosome ...
Naveed Ur Rehman +6 more
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Biomedicines, 2022 Alzheimer’s disease (AD) is one of the most prevailing neurodegenerative diseases in the world, which is characterized by memory dysfunction and the formation of tau and amyloid β (Aβ) aggregates in multiple brain regions, including the hippocampus and ...
Md. Ataur Rahman +6 more
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The Expandables: Cracking the Staphylococcal Cell Wall for Expansion Microscopy
Frontiers in Cellular and Infection Microbiology, 2021 Expansion Microscopy (ExM) is a novel tool improving the resolution of fluorescence microscopy by linking the sample into a hydrogel that gets physically expanded in water.
Tobias C. Kunz +6 more
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How Lipids Contribute to Autophagosome Biogenesis, a Critical Process in Plant Responses to Stresses
Cells, 2021 Throughout their life cycle, plants face a tremendous number of environmental and developmental stresses. To respond to these different constraints, they have developed a set of refined intracellular systems including autophagy.
Rodrigo Enrique Gomez +7 more
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Applied Sciences, 2022 The aim of the study was to assess the effects of therapeutic ultrasound (US) on oxidative stress (OS)-induced changes in cultured human chondrocytes (HCH). For this, monolayer HCH were randomized in three groups: a control group (CG), a group exposed to
Rodica Ana Ungur +14 more
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Molecular Mind Games: The Medicinal Action of Cyclodextrins in Neurodegenerative Diseases
Biomolecules, 2023 Cyclodextrins are often used as molecular carriers for small active ingredients in medicine. Recently, the intrinsic medicinal activity of some of these compounds has been under investigation, mainly related to their ability to interfere with cholesterol
Susana Santos Braga
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Rabies Virus-Induced Autophagy Is Dependent on Viral Load in BV2 Cells
Frontiers in Microbiology, 2021 An increasing number of studies are showing that autophagy plays a vital role in viral replication and escape. Rabies virus (RABV), a typical neurotropic virus, has been proven to induce autophagy in neurons. However, there are no reports indicating that
Yang Wang +10 more
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Frontiers in Cardiovascular Medicine, 2022 Exploring effective methods to lessen myocardial ischemia-reperfusion injury still has positive significance. The adenosine A2a receptor (A2aR) has played a crucial part in cardiac ischemia-reperfusion injury. Previous studies revealed that the adenosine
Yun Xia +9 more
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