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Correction to "IGF2BP3-Dependent N6-Methyladenosine Modification of USP49 Promotes Carboplatin Resistance in Retinoblastoma by Enhancing Autophagy via Regulating the Stabilization of SIRT1". [PDF]
europepmc +1 more source
Autophagy Modulation in Cancer Therapy: Navigating the Dual Roles to Overcome Chemoresistance. [PDF]
Mohiuddin M, Ahsan MAM.
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Autophagy in Osx1-Cre-targeted cells is essential for development, growth, and maintenance of bone. [PDF]
James A +8 more
europepmc +1 more source
Proteostasis in the regulation of pancreatic islet cell plasticity. [PDF]
Shirakawa J.
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Polymer Concepts in Cellular Function
Advanced Science, EarlyView.
Miao Yu +7 more
wiley +1 more source
Autophagy and autophagy-related pathways in cancer
Maintenance of protein homeostasis and organelle integrity and function is critical for cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates the delivery of various cellular cargoes to lysosomes for degradation and recycling. A myriad of studies demonstrate important protective roles for autophagy against disease.
Noor Gammoh +2 more
exaly +5 more sources
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1996
Autophagy or autophagocytosis are terms given to a membrane-mediated process in eukaryotic cells in which portions of cytoplasm are sequestered within vacuoles and degraded by acid hydrolases that are acquired by fusion with lysosomes. Although vacuoles of this type may be formed under pathologic conditions, autophagy is fundamentally a physiologic ...
MORTIMORE G. E. +3 more
openaire +3 more sources
Autophagy or autophagocytosis are terms given to a membrane-mediated process in eukaryotic cells in which portions of cytoplasm are sequestered within vacuoles and degraded by acid hydrolases that are acquired by fusion with lysosomes. Although vacuoles of this type may be formed under pathologic conditions, autophagy is fundamentally a physiologic ...
MORTIMORE G. E. +3 more
openaire +3 more sources
Autophagy in Huntington disease and huntingtin in autophagy
Trends in Neurosciences, 2015Autophagy is an important biological process that is essential for the removal of damaged organelles and toxic or aggregated proteins by delivering them to the lysosome for degradation. Consequently, autophagy has become a primary target for the treatment of neurodegenerative diseases that involve aggregating proteins.
Dale D O, Martin +3 more
openaire +2 more sources

