Results 261 to 270 of about 373,644 (316)

Stage-dependent Expression of Autophagy-related Genes in Patients With Knee Osteoarthritis. [PDF]

In Vivo
Ök ZD, Gürbüz ME, Ök N, Lengerova G, Bozhkova M, Petrov S, Köseler A.   +6 more
europepmc   +1 more source

Synergistic Remodeling of Tumor Immune Microenvironment via a DNA Nanodevice Integrating STING Activation and Lysosome‐Targeted PD‐L1 Degradation

Advanced Science, EarlyView.
A rational design DNA nanoplatform not only achieves efficient PD‐L1 degradation but also triggers robust STING signaling. The nanodevice effectively reprograms “cold” tumors, leading to potent inhibition of tumor growth and metastasis in vivo. ABSTRACT The cGAS‐STING pathway is a cornerstone of innate antitumor immunity; however, its therapeutic ...
Haoxiang Li, Min Hou, Shasha Sun, Jun Cao, Jian‐Hui Jiang, Jianjun He   +5 more
wiley   +1 more source

DDIT3 Promotes Starvation-Induced Autophagy via ER Stress in Vero Cells. [PDF]

Int J Mol Sci
Li M, Jia R, Huang R, Wang J, Qiao Z, Sun N.   +5 more
europepmc   +1 more source

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cellsduring Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

Unraveling the Predictive Value of <i>HGF</i>, <i>RECK</i>, <i>CYP1B1</i>, and <i>ZEB2</i> for Cancer Stemness and Immune Microenvironment in Pancreatic Adenocarcinoma. [PDF]

Stem Cells Int
Chen H, Song S, Li C, Yu Z.
europepmc   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

NBR1-Mediated Selective Autophagy in Plant Development and Stress Responses. [PDF]

Plants (Basel)
Li X, Duan Y, Zhou J, Yu P.
europepmc   +1 more source

Tumor stage-dependent expression of autophagy proteins in adrenocortical carcinoma. [PDF]

Front Endocrinol (Lausanne)
Oliveira SB, Sousa D, Costa M, Rios E, Nunes da Silva T, Leite V, Pereira SS, Pignatelli D.   +7 more
europepmc   +1 more source

The emerging role and therapeutic targeting of autophagy-lysosome pathway in the pathogenesis of Parkinson's disease. [PDF]

Transl Neurodegener
Shimizu T, Isik S, Kamath N, Yue Z.
europepmc   +1 more source

Pharmacological restoration of impaired autophagy in retinal ganglion cells prevents abnormal mitochondrial accumulation and glaucomatous neurodegeneration. [PDF]

Mol Neurodegener
Maddineni P, Kaipa BR, Kodati B, Kesavan K, Li L, Millar JC, Yacoub S, Kasetti RB, Clark AF, Zode GS.   +9 more
europepmc   +1 more source