Results 71 to 80 of about 116,566 (305)

Identification of autophagy-related risk signatures for the prognosis, diagnosis, and targeted therapy in cervical cancer

Cancer Cell International, 2021
Background To rummage autophagy-related prognostic, diagnostic, and therapeutic biomarkers in cervical cancer (CC). Methods The RNA-sequence and clinical information were from the TCGA and GTEx databases.
Dan Meng, Hua Jin, Xing Zhang, Wenjing Yan, Qianqian Xia, Siyuan Shen, Shuqian Xie, Mengjing Cui, Bo Ding, Yun Gu, Shizhi Wang   +10 more
doaj   +1 more source

The Role of Autophagy in Osteoarthritic Cartilage

Biomolecules, 2022
Osteoarthritis (OA) is one of the most common diseases leading to physical disability, with age being the main risk factor, and degeneration of articular cartilage is the main focus for the pathogenesis of OA.
Wei-Chun Kao, Jian-Chih Chen, Ping-Cheng Liu, Cheng-Chang Lu, Sung-Yen Lin, Shu-Chun Chuang, Shun-Cheng Wu, Ling-hua Chang, Mon-Juan Lee, Chung-Da Yang, Tien-Ching Lee, Ying-Chun Wang, Jhong-You Li, Chun-Wang Wei, Chung-Hwan Chen   +14 more
doaj   +1 more source

Ibuprofen Ameliorates Fatigue- And Depressive-Like Behavior in Tumor-Bearing Mice [PDF]

, 2015
Aims: Cancer-related fatigue (CRF) is often accompanied by depressed mood, both of which reduce functional status and quality of life. Research suggests that increased expression of pro-inflammatory cytokines is associated with skeletal muscle wasting ...
Bicer, Sabahattin, Devine, Raymond, Godbout, Jonathan P., McCarthy, Donna O., Norden, Diana M., Reiser, Peter J., Wold, Loren E.   +6 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Regulation of autophagy by microRNAs in human breast cancer

Journal of Biomedical Science, 2021
Breast cancer is the most common solid cancer that affects female population globally. MicroRNAs (miRNAs) are short non-coding RNAs that can regulate post-transcriptional modification of multiple downstream genes.
Zhi Xiong Chong, Swee Keong Yeap, Wan Yong Ho   +2 more
doaj   +1 more source

Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]

, 2018
Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F., Ferrante A., Guggino G., Rizzo A.   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson’s Disease

Clinical and Translational Science, 2021
The current diagnosis of Parkinson’s disease (PD) mostly relies on clinical rating scales related to motor dysfunction. Given that clinical symptoms of PD appear after significant neuronal cell death in the brain, it is required to identify accessible ...
Juhee Kang, Jae Whan Kim, Hansol Heo, Jihyun Lee, Kwan Yong Park, Jung Han Yoon, Jaerak Chang   +6 more
doaj   +1 more source

Inhibition of Autophagy Signaling via 3-methyladenine Rescued Nicotine-Mediated Cardiac Pathological Effects and Heart Dysfunctions. [PDF]

, 2020
Rationale: Cigarette smoking is a well-established risk factor for myocardial infarction and sudden cardiac death. The deleterious effects are mainly due to nicotine, but the mechanisms involved and theranostics remain unclear.
Fu, Yingjie, Huang, Lei, Li, Yong, Liu, Bailin, Shao, Xuesi M, Xiao, Daliao, Zhang, Lubo, Zhang, Peng   +7 more
core  

Can agricultural cultivation methods influence the healthfulness of crops for foods [PDF]

, 2012
The aim of the current study was to investigate if there are any health effects of long-term consumption of organically grown crops using a rat model. Crops were retrieved over two years from along-term field trial at three different locations in Denmark ...
Association of Official Analytical Chemists, Baranska A. M., Bligh E. G., Bondy G. S., Bourn D., Brandt K., Brunsgaard G., Charlotte Lauridsen, Dangour A. D., Dangour A. D., Das U. N., Demas G. E., Eppendorfer W. H., Finamore A., Fritsche K., Godecke R., Harker F. R., Henry Jørgensen, Huber M., Huber M., Jensen S. K., Jensen S. K., Josefsen L., Jørgen E. Olesen, Jørgensen H., Kaku S., Kall M. A., Knudsen K. E. B., Lauridsen C., Laursen K. H., Magkos F., Maja M. Jensen, Malmauret L., Meydani S. N., National Research Council, Nelson L., Olesen J. E., O’Brien L., Parmentier H. K., Parmentier H. K., Penn N. D., Rosen J. D., Rotenberg S., Schneweis I., Sulyok M., Ulrich Halekoh, van Ommen B., Velimirov A., Wier M., Woese K., Worthington V., Yiridoe E. K.   +51 more
core   +1 more source