Results 11 to 20 of about 1,572 (116)

Genetic Background and Inbreeding Depression in Romosinuano Cattle Breed in Mexico

open access: yesAnimals, 2021
The ultimate goal of genetic selection is to improve genetic progress by increasing favorable alleles in the population. However, with selection, homozygosity, and potentially harmful recessive alleles can accumulate, deteriorating genetic variability ...
Jorge Hidalgo   +8 more
doaj   +1 more source

Assessment and Distribution of Runs of Homozygosity in Horse Breeds Representing Different Utility Types

open access: yesAnimals, 2022
The present study reports runs of homozygosity (ROH) distribution in the genomes of six horse breeds (571 horses in total) representing three horse types (primitive, light, and draft horses) based on the 65k Equine BeadChip assay.
Tomasz Szmatoła   +8 more
doaj   +1 more source

Pedigree and genome-based patterns of homozygosity in the South African Ayrshire, Holstein, and Jersey breeds

open access: yesFrontiers in Genetics, 2023
The erosion of genetic diversity limits long-term genetic gain and impedes the sustainability of livestock production. In the South African (SA) dairy industry, the major commercial dairy breeds have been applying estimated breeding values (EBVs) and/or ...
Carina Visser   +5 more
doaj   +1 more source

Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer’s Disease

open access: yesFrontiers in Genetics, 2021
Prior work in late-onset Alzheimer’s disease (LOAD) has resulted in discrepant findings as to whether recent consanguinity and outbred autozygosity are associated with LOAD risk.
Valerio Napolioni   +4 more
doaj   +1 more source

Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms

open access: yesBMC Genomics, 2011
Background A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identical by descent) on phenotypes ...
Simonson Matthew A   +2 more
doaj   +1 more source

GENOMIC VARIABILITY AMONG CATTLE POPULATIONS BASED ON RUNS OF HOMOZYGOSITY [PDF]

open access: yesPoljoprivreda, 2015
In this work, the distribution of different lengths ROH (runs of homozygosity) in six cattle breeds was described. A total of 122 animals from six cattle breeds (Holstein, Simmental, Austrian Pinzgau, Ayrshire, MRI-Meuse Rhine Issel and Slovak Pinzgau ...
Veronika Šidlová   +5 more
doaj   +1 more source

Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics.

open access: yesPLoS Genetics, 2009
This research investigates the influence of demographic factors on human genetic sub-structure. In our discovery cohort, we show significant demographic trends for decreasing autozygosity associated with population variation in chronological age ...
Michael A Nalls   +12 more
doaj   +1 more source

Fine-scale analysis of six beef cattle breeds revealed patterns of their genomic diversity

open access: yesItalian Journal of Animal Science, 2020
There has been a significant decrease in genetic diversity on a global scale for several livestock species, including beef cattle. Therefore, the aim of this study was to deliver fine-scale analysis of the genomic structure and to describe the diversity ...
Radovan Kasarda   +12 more
doaj   +1 more source

Analysis of Autozygosity Using Whole-Genome Sequence Data of Full-Sib Families in Pikeperch (Sander lucioperca)

open access: yesFrontiers in Genetics, 2022
Pikeperch (Sander lucioperca) has emerged as a high value species to the aquaculture industry. However, its farming techniques are at an early stage and its production is often performed without a selective breeding program, potentially leading to high ...
Lidia De los Ríos-Pérez   +4 more
doaj   +1 more source

Autozygosity and Genetic Differentiation of Landrace and Large White Pigs as Revealed by the Genetic Analyses of Crossbreds

open access: yesFrontiers in Genetics, 2019
Genomic information from crossbreds is routinely generated for genomic evaluations. The objective of this study is to investigate autozygosity and genetic differentiation in Landrace by Large-White breeds by using the genotypic information of SNP arrays ...
Luis Gomez-Raya   +5 more
doaj   +1 more source

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