Multiple Antioxidative and Bioactive Molecules of Oats (Avena sativa L.) in Human Health
Antioxidants, 2021 Oats (Avena sativa L.) are rich in protein, fiber, calcium, vitamins (B, C, E, and K), amino acids, and antioxidants (beta-carotene, polyphenols, chlorophyll, and flavonoids).
Il-Sup Kim +3 more
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Materials Today Bio, 2022 Chemodynamic therapy (CDT) is a promising tumor-specific treatment, but still suffering insufficient reactive oxygen species (ROS) levels due to its limited efficacy of Fenton/Fenton-like reaction.
Huijia Mao +5 more
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Phytochemicals attenuating aberrant activation of β-catenin in cancer cells. [PDF]
PLoS ONE, 2012 Phytochemicals are a rich source of chemoprevention agents but their effects on modulating the Wnt/β-catenin signaling pathway have remained largely uninvestigated. Aberrantly activated Wnt signaling can result in the abnormal stabilization of β-catenin,
Dan Wang +3 more
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Ferulic acid derivatives and avenanthramides modulate endothelial function through maintenance of nitric oxide balance in huvec cells [PDF]
, 2021 Wholegrain oats contain a variety of phenolic compounds thought to help maintain healthy vascular function, through the maintenance of local levels of the vasodilator nitric oxide (NO). Thus, the full molecular mechanisms involved are not yet clear. With
Corona G. +8 more
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Journal of the International Society of Sports Nutrition, 2020 Background Avenanthramides (AVA) are a group of di-phenolic acids found only in oats and have shown antioxidant and anti-inflammatory effects in vitro and in vivo.
Tianou Zhang +8 more
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Efficiency of antioxidant Avenanthramide-C on high-dose methotrexate-induced ototoxicity in mice.
PLoS ONE, 2022 Methotrexate (MTX) has been used in treating various types of cancers but can also cause damage to normal organs and cell types. Folinic acid (FA) is a well-known MTX antidote that protects against toxicity caused by the drug and has been used for ...
Alphonse Umugire +3 more
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Assessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches [PDF]
, 2021 Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties
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The Adapted POM Analysis of Avenanthramides In Silico
Pharmaceuticals, 2023 POM analysis and related approaches are significant tools based on calculating various physico-chemical properties and predicting biological activity, ADME parameters, and toxicity of a molecule. These methods are used to evaluate a molecule’s potential to become a drug candidate.
Tibor Maliar +8 more
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New series of avenanthramides in oat seed
Bioscience, Biotechnology, and Biochemistry, 2014 Abstract Avenanthramides are characteristic constituents of oat seeds. We analyzed the methanol extract of oat seeds by HPLC and detected three compounds 1, 2, and 3 eluted at retention times similar to avenanthramides. The three compounds were purified by column chromatography and HPLC.
Atsushi, Ishihara +4 more
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Gastrointestinal Tumors: Phytochemical and Drug Combinations Targeting the Hallmarks of Cancer [PDF]
, 2021 Cancer is a worldwide burden resulting in millions of deaths each year. In particular, gastrointestinal tumors are life-threatening malignancies and one of the leading reasons for death in developed countries.
Giammanco, Marco +2 more
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