Results 31 to 40 of about 6,031 (179)

The Biosynthetic Pathway of Major Avenanthramides in Oat [PDF]

Metabolites, 2019
Avenanthramides are a group of N-cinnamoylanthranilic acids, with health-promoting properties mainly found in oat (Avena sativa L.). However, the biosynthetic mechanism for the main three types of avenanthramides (Avn-A, Avn-B and Avn-C) is not completely understood.
Zhiyong Li, Yi Chen, Dauenpen Meesapyodsuk, Xiao Qiu   +3 more
openaire   +3 more sources

Avenanthramide Improves Colonic Damage Induced by Food Allergies in Mice through Altering Gut Microbiota and Regulating Hsp70-NF-κB Signaling. [PDF]

Nutrients, 2023
Food allergies can cause intestinal damage that can exacerbate allergic symptoms, and gut microbiota have been shown to influence allergic development. This study was intended to investigate the effects of Avenanthramide (AVA) on colonic damage induced ...
Liu P, Zhang M, Liu T, Mo R, Wang H, Zhang G, Wu Y.   +6 more
europepmc   +2 more sources

Effects of Avenanthramide on the Small Intestinal Damage through Hsp70-NF-κB Signaling in an Ovalbumin-Induced Food Allergy Model. [PDF]

Int J Mol Sci, 2022
A food allergy is caused by an abnormal immune reaction and can induce serious intestinal inflammation and tissue damage. Currently, the avoidance of food allergens is still the most effective way to prevent or reduce allergic symptoms, so the ...
Liu P, Liu T, Zhang M, Mo R, Zhou W, Li D, Wu Y.   +6 more
europepmc   +2 more sources

Avenanthramide-C Mitigates High-Fat Diet-Accelerated Alzheimer's Pathologies via NOD1-Driven Neuroinflammation in 5×FAD Mice. [PDF]

Nutrients
Background: Obesity is clinically known to be associated with an increased risk and aggravated pathology of Alzheimer’s disease (AD). A high-fat diet (HFD), the major contributor to obesity, induces neuroinflammation and central insulin resistance,
Wang M, Jin B, Xu J, Wang C.
europepmc   +2 more sources

Efficiency of antioxidant Avenanthramide-C on high-dose methotrexate-induced ototoxicity in mice.

PLoS ONE, 2022
Methotrexate (MTX) has been used in treating various types of cancers but can also cause damage to normal organs and cell types. Folinic acid (FA) is a well-known MTX antidote that protects against toxicity caused by the drug and has been used for ...
Alphonse Umugire, Youngmi Choi, Sungsu Lee, Hyong-Ho Cho   +3 more
doaj   +1 more source

Ferulic acid derivatives and avenanthramides modulate endothelial function through maintenance of nitric oxide balance in huvec cells [PDF]

, 2021
Wholegrain oats contain a variety of phenolic compounds thought to help maintain healthy vascular function, through the maintenance of local levels of the vasodilator nitric oxide (NO). Thus, the full molecular mechanisms involved are not yet clear. With
Serreli G., Dhunna M. A., Deiana M., Spencer J. P. E., Lacour C., Thou E., Diotallevi C., Corona G., Le Sayec M.   +8 more
core   +2 more sources

Synergistic Effect of Methyl Jasmonate and Abscisic Acid Co-Treatment on Avenanthramide Production in Germinating Oats

, 2021
The oat (Avena sativa L.) is a grain of the Poaceae grass family and contains many powerful anti-oxidants, including avenanthramides as phenolic alkaloids with anti-inflammatory, anti-oxidant, anti-itch, anti-irritant, and anti-atherogenic activities ...
Cha Young Kim, Tae Hee Kim, Su Hyun Park, Yu Jeong Jeong, Jae Cheol Jeong, K Y Yang, Sung Chul Park, Soyoung Kim, Jiyoung Lee, Kwang Yeol Yang   +9 more
core   +1 more source

New series of avenanthramides in oat seed

Bioscience, Biotechnology, and Biochemistry, 2014
Abstract Avenanthramides are characteristic constituents of oat seeds. We analyzed the methanol extract of oat seeds by HPLC and detected three compounds 1, 2, and 3 eluted at retention times similar to avenanthramides. The three compounds were purified by column chromatography and HPLC.
Atsushi, Ishihara, Kana, Kojima, Takeshi, Fujita, Yuya, Yamamoto, Hiromitsu, Nakajima   +4 more
openaire   +3 more sources

Overview of the Anticancer Profile of Avenanthramides from Oat [PDF]

International Journal of Molecular Sciences, 2019
Cancer represents one of the leading causes of death worldwide. Progresses in treatment of cancer have continued at a rapid pace. However, undesirable side effects and drug resistance remain major challenges for therapeutic success. Natural products represent a valuable starting point to develop new anticancer strategies.
Turrini E, Maffei F, Milelli A, Calcabrini C, Fimognari C   +4 more
openaire   +2 more sources

Simplified Analysis and Expanded Profiles of Avenanthramides in Oat Grains [PDF]

Foods, 2022
Uniquely, oats contain avenanthramides (AVAs), a group of phenolic alkaloids, exhibiting many health benefits. AVA analysis involves extraction with alcohol-based solvents and HPLC separation with UV and/or mass spectrometer detectors. There are many reported methods to extract AVAs. Almost all entail multiple extractions.
Mike Woolman, Keshun Liu
openaire   +3 more sources