Results 111 to 120 of about 12,023 (194)

Synergistic Effect of Ceftazidime-Avibactam with Aztreonam on Carbapenemase-Positive Klebsiella pneumoniae MBL+, NDM+

open access: yes
Mateusz Szymański,1,2 Małgorzata M Skiba,2 Małgorzata Piasecka,2 Alina Olender3 1Human Anatomy Department, Medical University, Lublin, Poland; 2Intensive Care Unit, Stefan Cardinal Wyszyński District Specialist Hospital ...
Szymański M   +3 more
core  

Enhancement and Comparison of (Ceftazidime-)Avibactam Plus Aztreonam Susceptibility Tests for Stenotrophomonas maltophilia in Clinical Diagnostics [PDF]

open access: yes
Stenotrophomonas maltophilia is naturally resistant to many antimicrobials. We evaluated the in vitro activity and reproducibility of two different super-position methods of aztreonam in combination with ceftazidime-avibactam for S.
Huis in ’t Veld, Robert A.G.   +4 more
core   +1 more source

**In vitro** antibacterial activity of the ceftazidime-avibactam (NXL104) combination against **Pseudomonas aeruginosa** clinical isolates

open access: yes, 2012
: The beta-lactamase inhibitor avibactam (NXL104) displays potent inhibition of both class A and C enzymes. The in vitro antibacterial activity of the combination ceftazidime-avibactam was evaluated against a clinical panel of Pseudomonas aeruginosa ...
Goossens, Herman   +6 more
core  

Chemical structure of avibactam, RPX7009, and compounds 9a and 11a.

open access: yes, 2018
Chemical structure of avibactam, RPX7009, and compounds 9a and 11a.
Pasquale Linciano (4426435)   +8 more
core   +1 more source

Antimicrobial Resistance Profiles of Pseudomonas aeruginosa in a Korean Community Hospital: In Vitro Activity of Ceftazidime-Avibactam and Other Agents

open access: yesPolish Journal of Microbiology
The novel antibiotic ceftazidime-avibactam was introduced in Korea in 2023. This study evaluated the in vitro susceptibility of Pseudomonas aeruginosa isolates from a community-based hospital to various antibiotics, including ceftazidime-avibactam.
Lee Hyo-Jin   +6 more
doaj   +1 more source

Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa

open access: yes, 2017
Objectives: When tested in broth, avibactam reverses ceftazidime resistance in many Pseudomonas aeruginosa that express ESBLs. We examined whether similar reversal is observed against intracellular forms of P. aeruginosa.
Krause, K.M.   +6 more
core   +1 more source

Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam

open access: yes, 2018
Ceftazidime-avibactam is a “second-generation” β-lactam–β-lactamase inhibitor combination that is effective against Enterobacteriaceae expressing class A extended-spectrum β-lactamases, class A carbapenemases, and/or class C ...
Krisztina M. Papp-Wallace   +8 more
core   +1 more source

Elucidating the Molecular Basis of Avibactam Mediated Inhibition of Class A β-Lactamases

open access: yes, 2019
Disseminating antibiotic resistance rendered by bacteria against the widely used β-lactam antibiotics is a serious concern in the public health care.
Chandan Kumar Das (7474682)   +3 more
core   +1 more source

Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam

open access: yes, 2018
β-Lactamases (BLs) are important antibiotic-resistance determinants that significantly compromise the efficacy of valuable β-lactam antibacterial drugs. Thus, combinations with BL inhibitor were developed. Avibactam is the first non-β-lactam BL inhibitor
Flavio Di Pisa   +17 more
core   +1 more source

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