Results 131 to 140 of about 81,092 (236)

Ageing reveals the latent effects of early life stress on respiratory and metabolic function in female rats: Novel insights into the sex‐specific origins of sleep apnoea

open access: yesExperimental Physiology, Volume 111, Issue 3, Page 1466-1482, 1 March 2026.
Abstract Sleep apnoea (SA) is ∼2 times more prevalent in men than women. However, this changes at menopause as the occurrence of SA increases and matches that of men. Menopause is a natural process, but it remains unclear why SA emerges only in a subpopulation of ageing women.
Danuzia Ambrozio‐Marques   +4 more
wiley   +1 more source

Transport‐related effects on intrinsic and synaptic properties of human cortical neurons: A comparative study

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 2060-2082, 1 March 2026.
Abstract figure legend In this study, we investigated how transporting brain slices influences the electrophysiological and morphological properties of human cortical neurons. Whole‐cell patch‐clamp recordings were obtained from acute slices prepared from tissue collected during epilepsy or tumor surgeries, either on‐site or off‐site, after ...
Guanxiao Qi   +7 more
wiley   +1 more source

The pyrogenic mediator prostaglandin E2 elicits warmth seeking via EP3 receptor‐expressing parabrachial neurons: a potential mechanism of chills

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 2110-2130, 1 March 2026.
Abstract figure legend During infection, prostaglandin E2 (PGE2) is produced and elicits warmth‐seeking behaviour and involuntary febrile responses by acting on prostaglandin EP3 receptors (EP3Rs) in two distinct brain sites. PGE2 acting on EP3Rs on neurons in the external lateral part of the lateral parabrachial nucleus (LPBel) augments cold sensory ...
Takaki Yahiro   +2 more
wiley   +1 more source

Direct‐to‐Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery

open access: yesChemMedChem, Volume 21, Issue 4, 25 February 2026.
Crude yet clever: Direct‐to‐biology workflows exploit nanoscale synthesis and plate‐based assays to accelerate hit discovery, save precious intermediates, and rethink early drug discovery. Direct‐to‐biology (D2B) has emerged as a transformative concept in early drug discovery, defined by the direct on‐target screening of crude reaction mixtures without
Ariane F. Hübner, Fabian Barthels
wiley   +1 more source

Quantitative SERS-Based Sandwich-Hybridization Assay for Nucleic Acid Detection. [PDF]

open access: yesACS Omega
Shahsavar K   +6 more
europepmc   +1 more source

Selbstassemblierte (Aza‐)BODIPY Farbstoffe für Biomedizinische In Vivo Bildgebung

open access: yesAngewandte Chemie, Volume 138, Issue 8, 16 February 2026.
Dieses Minireview klassifiziert (Aza‐)BODIPY‐Farbstoffe anhand ihrer molekularen Stapelungsmodi und Aggregattypen (H‐, oblique‐ oder J‐Typ) in wässrigen Medien und setzt diese Merkmale in Beziehung zu ihrer multimodalen Bildgebungsleistung. Durch die Verknüpfung von molekularem Design, Exzitonenkopplung und pfadabhängiger Assemblierung stellen wir ...
Antonia Albers   +2 more
wiley   +1 more source

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