Results 171 to 180 of about 136,222 (342)

Age‐Dependent KLK8 Upregulation Contributes to Elevated Susceptibility to Ventilator‐Induced Lung Injury in the Elderly Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Our research firstly indicated that age‐dependent upregulation of tissue kallikrein‐related peptidase 8 (KLK8) induces endothelial senescence through modulating the fibronectin‐FAK‐Akt‐PARP1/2 axis, thereby increasing the vulnerability of aged mice to low‐tidal‐volume ventilator‐induced lung injury (VILI).
Di Liu   +7 more
wiley   +1 more source

Self‐Organizing Ovarian Somatic Organoids Preserve Cellular Heterogeneity and Reveal Cellular Contributions to Ovarian Aging

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
We report the development and application of a mouse ovarian somatic organoid model to elucidate a fundamental new understanding of the cell biology of the aging ovarian microenvironment. ABSTRACT Ovarian somatic cells are essential for reproductive function, but no existing ex vivo models recapitulate the cellular heterogeneity or interactions within ...
Shweta S. Dipali   +10 more
wiley   +1 more source

Correction to: Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling. [PDF]

open access: yesCell Oncol (Dordr)
Pozios I   +10 more
europepmc   +1 more source

Effects of neonatal hypothyroidism on testicular development and undifferentiated spermatogonia in prepubertal rats

open access: yesAndrology, Volume 14, Issue 1, Page 196-209, January 2026.
Abstract Background Thyroid hormones play a key role in testicular development, particularly in the regulation of Sertoli cell proliferation and differentiation. While congenital hypothyroidism is common and treatable, the effects of thyroid hormone insufficiency on early testicular development during the neonatal period remain unclear. Objectives This
Daisuke Matsumoto   +10 more
wiley   +1 more source

Tissue Distribution and Phenotype of Human Mast Cells in BRGSF and NSG-SGM3-IL15 Humanized Mice. [PDF]

open access: yesAllergy
Worrall WPM   +11 more
europepmc   +1 more source

Assembling of G-strands into novel tetra-molecular parallel G4-DNA nanostructures using avidin-biotin recognition [PDF]

open access: gold, 2008
Natalia Borovok   +6 more
openalex   +1 more source

Nitro‐oleic acid activation of endothelial PPARγ signaling pathway alleviates neurovascular injury and improves functional outcomes in ischemic stroke

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
OA‐NO2 activation of endothelial PPARγ signaling pathway alleviates ischemic brain injury. Endothelial OA‐NO2‐PPARγ signaling pathways preserve BBB integrity, reduce peripheral inflammatory cell infiltration, and improve functional outcomes after ischemic stroke.
Tianqing Xiong   +6 more
wiley   +1 more source

Multifunctional Peptide-Based Biohybrid for Targeted Reduction of Metastatic Breast Carcinoma-Associated Osteolysis. [PDF]

open access: yesJ Funct Biomater
Stadler N   +11 more
europepmc   +1 more source

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