Results 51 to 60 of about 90,586 (267)
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
The trifunctional l-cysteine containing carboxylic acid, amine and thiol is chemisorbed on the gold electrode surface via the thiol groups to form the self-assembled monolayer.
Nirgaman Bage +3 more
doaj +1 more source
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Similar to streptavidin, the binding of biotin by avidin does not appear to be cooperative in the traditional sense of altered binding strength, though it appears to be cooperative in terms of ligand induced structural communication across subunits in ...
Mark J. Waner +6 more
doaj +1 more source
Hormone-receptor studies with avidin and biotinylinsulin-avidin complexes.
Avidin can be labeled to high specific radioactivity by introducing 3-(p-hydroxyphenyl)-propionyl groups into the molecule (pHPP-avidin). 125I-pHPP-avidin binds avidly to rat liver plasma membranes and is not displaced by unlabeled pHPP-avidin. Nonspecific binding of 125I-pHPP-avidin can be substantially reduced by succinoylation of pHPP-avidin with ...
F M, Finn +3 more
openaire +2 more sources
Conjugated avidin binds to mast cell granules.
The glycoprotein, avidin, conjugated either to the enzyme horseradish peroxidase, or to the fluorochrome dyes, fluorescein or rhodamine, identifies the granules of mast cells in both tissues and cell suspensions.
M D Tharp +3 more
core +1 more source
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori +10 more
wiley +1 more source
Leukemia, the malignancy of the hematopoietic system accounts for 10% of cancer cases with poor overall survival rate in adults; therefore, there is a high unmet medical need for the development of novel therapeutics.
Gábor J. Szebeni +12 more
doaj +1 more source
Surface Acoustic Wave Biosensor with Laser-Deposited Gold Layer Having Controlled Porosity
Laser-deposited gold immobilization layers having different porosities were incorporated into love wave surface acoustic wave sensors (LW-SAWs). Variation of pulsed laser deposition parameters allows good control of the gold film morphology.
Dana Miu +3 more
doaj +1 more source
Multiple biotin-avidin amplification for multiple immunostaining
A multiple fluorescence immunostaining method is described, based on the use of multiple fluorochrome-avidin/streptavidin conjugates. Key factors are (a) stabilization of each (preceding) biotin-avidin chain and associated avidin blocking step with ...
Chiolerio, Francesca +4 more
core +1 more source

