Results 71 to 80 of about 90,586 (267)

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

open access: yesAdvanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler   +4 more
wiley   +1 more source

Engineering of charge, biotin-binding and oligomerization of avidin : new tools for avidin-biotin technology

open access: yes, 2002
Avidin is a tetrameric glycoprotein found in chicken egg white. Due to its remarkably high affinity for biotin, avidin has widely been used in biological and biotechnical applications in life sciences.
Marttila, Ari
core   +1 more source

Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein

open access: yesBMC Biotechnology, 2011
Background Engineered proteins, with non-immunoglobulin scaffolds, have become an important alternative to antibodies in many biotechnical and therapeutic applications.
Kulomaa Markku S   +9 more
doaj   +1 more source

Avidin Is a Slow-Binding Inhibitor of Pyruvate Carboxylase

open access: yes, 1982
In the presence of avidin, progress curves for the pyruvate carboxylase (EC 6.4.1.1) reaction show a marked decrease in the rate of reaction over a period of several minutes.
Wallace, John C.   +3 more
core   +1 more source

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy (Kerodon rupestris) and the common marmoset (Callithrix jacchus)

open access: yesThe Anatomical Record, EarlyView.
Abstract The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico‐subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild‐type ...
Lavínnya Yáskara de Aquino Matoso   +10 more
wiley   +1 more source

A monoclonal antibody to avidin dissociates quaternary structure and curtails biotin binding to avidin and streptavidin

open access: yes, 1997
An anti-avidin mAb, viz., H12G4, is shown to release bound biotin in a dose-dependent manner from holoavidin and holostreptavidin and inhibit the binding of ligand to the two apoproteins.
Karande, Anjali A.   +7 more
core   +1 more source

Goofy/123Cre lineage tracing differentiates olfactory and vomeronasal neurons from GnRH‐1 and terminal nerve neurons during neuronal migration and reveals additional olfactory placode‐derived cells in the brain

open access: yesDevelopmental Dynamics, EarlyView.
Abstract The olfactory placode (OP) generates a broad array of chemosensory neurons in the nasal region, including olfactory sensory neurons, vomeronasal sensory neurons, neurons of the septal organ, and Grueneberg ganglion. During invagination, the OP also generates migratory neuronal populations, including gonadotropin‐releasing hormone‐1 (GnRH‐1 ...
Enrico Amato Jr.   +5 more
wiley   +1 more source

Chemical linkage to injected tissues is a distinctive property of oxidized avidin.

open access: yesPLoS ONE, 2011
We recently reported that the oxidized avidin, named AvidinOX®, resides for weeks within injected tissues as a consequence of the formation of Schiff's bases between its aldehyde groups and tissue protein amino groups.
Rita De Santis   +9 more
doaj   +1 more source

Transgenic avidin maize is resistant to storage insect pests [PDF]

open access: yes, 2000
Avidin is a glycoprotein found in chicken egg white, that sequesters the vitamin biotin. Here we show that when present in maize at levels of ≥100 p.p.m., avidin is toxic to and prevents development of insects that damage grains during storage.
Morgan, Thomas D.   +11 more
core   +1 more source

Frequency of anti‐neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Autoimmune epilepsy (AES) is increasingly recognized as a condition in patients with epilepsy of unknown etiology. Early immunotherapy improves outcomes; however, data on its prevalence and the frequency of anti‐neural/neuronal antibodies in Asian populations remain scarce.
Seong Jin Park   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy