Results 11 to 20 of about 932,523 (265)

Human intraretinal myelination: Axon diameters and axon/myelin thickness ratios

open access: yesIndian Journal of Ophthalmology, 2013
Purpose: Human intraretinal myelination of ganglion cell axons occurs in about 1% of the population. We examined myelin thickness and axon diameter in human retinal specimens containing myelinated retinal ganglion cell axons.
Thomas FitzGibbon, Zoran Nestorovski
doaj   +4 more sources

Power-law for axon diameters at branch point [PDF]

open access: yesBMC Neuroscience, 2003
Background Axon calibers vary widely among different animals, neuron classes, and even within the same neuron. What determines the diameter of axon branches?
Stepanyants Armen, Chklovskii Dmitri B
doaj   +3 more sources

Axon diameter mapping using diffusion MRI [PDF]

open access: yes, 2017
Axon diameter plays a key role in the function and performance of nerve pathways of the central and peripheral nervous system. Therefore, there is a growing interest in imaging axon diameter non-invasively. One such technique is using diffusion MRI.
Kakkar, Lebina Shrestha
core   +3 more sources

Parametric Probability Distribution Functions for Axon Diameters of Corpus Callosum [PDF]

open access: yesFrontiers in Neuroanatomy, 2016
Axon diameter is an important neuroanatomical characteristic of the nervous system that alters in the course of neurological disorders such as multiple sclerosis. Axon diameters vary, even within a fiber bundle, and are not normally distributed.
Farshid eSepehrband   +8 more
doaj   +7 more sources

Novel insights into axon diameter and myelin content in late childhood and adolescence. [PDF]

open access: yesCereb Cortex, 2023
White matter microstructural development in late childhood and adolescence is driven predominantly by increasing axon density and myelin thickness. Ex vivo studies suggest that the increase in axon diameter drives developmental increases in axon density ...
Genc S   +4 more
europepmc   +2 more sources

Axon diameter and axonal transport: In vivo and in vitro effects of androgens. [PDF]

open access: yesNeuroimage, 2015
Testosterone is a sex hormone involved in brain maturation via multiple molecular mechanisms. Previous human studies described age-related changes in the overall volume and structural properties of white matter during male puberty. Based on this work, we have proposed that testosterone may induce a radial growth of the axon and, possibly, modulate ...
Pesaresi M   +5 more
europepmc   +4 more sources

Difference in axon diameter and myelin thickness between excitatory and inhibitory callosally projecting axons in mice. [PDF]

open access: yesCereb Cortex, 2023
Abstract Synchronization of network oscillation in spatially distant cortical areas is essential for normal brain activity. Precision in synchronization between hemispheres depends on the axonal conduction velocity, which is determined by physical parameters of the axons involved, including diameter, and extent of myelination. To compare
Basu K   +3 more
europepmc   +3 more sources

A high-resolution phenotypic screen identifies regulators of CNS axon diameter in zebrafish. [PDF]

open access: yesPLoS Biol
The molecular mechanisms underpinning neuronal morphogenesis remain to be fully understood. A powerful step in uncovering the molecular basis of biological processes is the execution of discovery screens in model systems.
Eichel-Vogel MA   +6 more
europepmc   +2 more sources

Tension Sensor Based on Fluorescence Resonance Energy Transfer Reveals Fiber Diameter-Dependent Mechanical Factors During Myelination

open access: yesFrontiers in Cellular Neuroscience, 2021
Oligodendrocytes (OLs) form a myelin sheath around neuronal axons to increase conduction velocity of action potential. Although both large and small diameter axons are intermingled in the central nervous system (CNS), the number of myelin wrapping is ...
Takeshi Shimizu   +9 more
doaj   +1 more source

A simple estimate of axon size with diffusion MRI

open access: yesNeuroImage, 2021
Noninvasive estimation of mean axon diameter presents a new opportunity to explore white matter plasticity, development, and pathology. Several diffusion-weighted MRI (DW-MRI) methods have been proposed to measure the average axon diameter in white ...
Kevin D Harkins   +4 more
doaj   +1 more source

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